Cowpox virus infection of cynomolgus macaques as a model of hemorrhagic smallpox

Virology

Volumn 418, Issue 2, 2011, Pages 102-112

  Johnson, Reed F ^a   Yellayi, Srikanth ^a   Cann, Jennifer A ^a   Johnson, Anthony ^a   Smith, Alvin L ^a   Paragas, Jason ^a   Jahrling, Peter B ^a   Blaney, Joseph E ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Animal model; Cowpox virus; Hemorrhagic disease; Orthopoxvirus; Pathogenesis; Smallpox; Variola virus

Indexed keywords

CD14 ANTIGEN; CD16 ANTIGEN; CD20 ANTIGEN; CD4 ANTIGEN; CD40 LIGAND; CD8 ANTIGEN; D DIMER; GAMMA INTERFERON; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HEMOGLOBIN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 15; INTERLEUKIN 17; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; TRANSFORMING GROWTH FACTOR ALPHA; VASCULOTROPIN;

ADAPTIVE IMMUNITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; BONE MARROW; CELL EXPANSION; CELL POPULATION; CLINICAL FEATURE; CLINICAL OBSERVATION; CONTROLLED STUDY; COWPOX VIRUS; COWPOX VIRUS INFECTION; DISEASE MODEL; DISEASE SEVERITY; DISSEMINATED INTRAVASCULAR CLOTTING; ERYTHROCYTE COUNT; EXPERIMENTAL INFECTION; HEMATOCRIT; HEMOGLOBIN BLOOD LEVEL; HEMORRHAGIC SMALLPOX; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INFLAMMATORY INFILTRATE; INNATE IMMUNITY; INOCULATION; LETHALITY; LUNG; LYMPH NODE; MACACA FASCICULARIS; NONHUMAN; PARTIAL THROMBOPLASTIN TIME; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTHROMBIN TIME; SMALLPOX; SPLEEN; THROMBOCYTOPENIA; THYMUS; TONSIL; VIREMIA; VIRUS INFECTION; VIRUS REPLICATION; VIRUS STRAIN;

ANIMALS; COWPOX; COWPOX VIRUS; CYTOKINES; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HEMORRHAGE; IMMUNITY, INNATE; LEUKOCYTES, MONONUCLEAR; MACACA FASCICULARIS; SMALLPOX; VIRAL LOAD; VIRUS REPLICATION;

ANIMALIA; COWPOX VIRUS; MACACA; MACACA FASCICULARIS; ORTHOPOXVIRUS; PRIMATES; VARIOLA VIRUS;

EID: 80052109447     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2011.07.013     Document Type: Article

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