-
1
-
-
0034721644
-
Protein diversity from alternative splicing: A challenge for bioinformatics and post-genome biology
-
Black D L, Protein diversity from alternative splicing: a challenge for bioinformatics and post-genome biology, Cell, 103 (2000) 367.
-
(2000)
Cell
, vol.103
, pp. 367
-
-
Black, D.L.1
-
2
-
-
0035252410
-
Alternative splicing: Increasing diversity in the proteomic world
-
Graveley B R, Alternative splicing: increasing diversity in the proteomic world, Trends Genet, 17 (2001) 100.
-
(2001)
Trends Genet
, vol.17
, pp. 100
-
-
Graveley, B.R.1
-
3
-
-
33745251706
-
Distinct expression profiles for PTEN transcript and its splice variants in Cowden syndrome and Bannayan-Riley-Ruvalcaba syndrome
-
Sarquis M S, Agrawal S, Shen L, Pilarski R, Zhou X P & Eng C, Distinct expression profiles for PTEN transcript and its splice variants in Cowden syndrome and Bannayan-Riley-Ruvalcaba syndrome, Am J Hum Genet, 79 (2006) 23.
-
(2006)
Am J Hum Genet
, vol.79
, pp. 23
-
-
Sarquis, M.S.1
Agrawal, S.2
Shen, L.3
Pilarski, R.4
Zhou, X.P.5
Eng, C.6
-
4
-
-
1542515338
-
A census of human cancer genes
-
Futreal P A, Coin L, Marshall M, Down T, Hubbard T, Wooster R, Rahman N & Stratton M R, A census of human cancer genes, Nat Rev Cancer, 4 (2004) 177.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 177
-
-
Futreal, P.A.1
Coin, L.2
Marshall, M.3
Down, T.4
Hubbard, T.5
Wooster, R.6
Rahman, N.7
Stratton, M.R.8
-
5
-
-
0345686789
-
The generation and utilization of a cancer-oriented representation of the human transcriptome by using expressed sequence tags
-
Brentani H, Caballero O L Camargo A A, et al., The generation and utilization of a cancer-oriented representation of the human transcriptome by using expressed sequence tags, Proc Natl Acad Sci U S A, 100 (2003) 13418.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 13418
-
-
Brentani, H.1
Caballero, O.L.2
Camargo, A.A.3
-
6
-
-
0141974926
-
Discovery of novel splice forms and functional analysis of cancer-specific alternative splicing in human expressed sequences
-
Xu Q & Lee C: Discovery of novel splice forms and functional analysis of cancer-specific alternative splicing in human expressed sequences, Nucleic Acids Res, 31 (2003) 5635.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 5635
-
-
Xu, Q.1
Lee, C.2
-
7
-
-
9144258614
-
Strengths and weaknesses of EST-based prediction of tissue-specific alternative splicing
-
Gupta S, Zink D, Korn B, Vingron M & Haas S A, Strengths and weaknesses of EST-based prediction of tissue-specific alternative splicing, BMC Genomics, 5 (2004) 72.
-
(2004)
BMC Genomics
, vol.5
, pp. 72
-
-
Gupta, S.1
Zink, D.2
Korn, B.3
Vingron, M.4
Haas, S.A.5
-
8
-
-
79952850691
-
Osteopontin-c splicing isoform contributes to ovarian cancer progression
-
Tilli T M, Franco V F, Robbs B K, Wanderley J L, da Silva F R, de Mello K D, Viola J P, Weber G F & Gimba E R, Osteopontin-c splicing isoform contributes to ovarian cancer progression, Mol Cancer Res, 9 (2011) 280.
-
(2011)
Mol Cancer Res
, vol.9
, pp. 280
-
-
Tilli, T.M.1
Franco, V.F.2
Robbs, B.K.3
Wanderley, J.L.4
da Silva, F.R.5
de Mello, K.D.6
Viola, J.P.7
Weber, G.F.8
Gimba, E.R.9
-
9
-
-
79957927217
-
Silencing survivin splice variant 2B Leads to antitumor activity in taxane-resistant ovarian cancer
-
Vivas-Mejia P E, Rodriguez-Aguayo C, Han H, Shahzad M M K, Valiyeva F, Shibayama M, Chavez-Reyes A, Sood A K & Lopez-Berestein G, Silencing survivin splice variant 2B Leads to antitumor activity in taxane-resistant ovarian cancer, Clin Cancer Res, 17 (2011) 3716.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 3716
-
-
Vivas-Mejia, P.E.1
Rodriguez-Aguayo, C.2
Han, H.3
Shahzad, M.M.K.4
Valiyeva, F.5
Shibayama, M.6
Chavez-Reyes, A.7
Sood, A.K.8
Lopez-Berestein, G.9
-
10
-
-
79959980417
-
Novel splice variant CAR 4/6 of the coxsackie adenovirus receptor is differentially expressed in cervical carcinogenesis
-
Dietel M, Häfner N, Jansen L, Dürst M & Runnebaum IB, Novel splice variant CAR 4/6 of the coxsackie adenovirus receptor is differentially expressed in cervical carcinogenesis, J Mol Med, 89 (2011) 621.
-
(2011)
J Mol Med
, vol.89
, pp. 621
-
-
Dietel, M.1
Häfner, N.2
Jansen, L.3
Dürst, M.4
Runnebaum, I.B.5
-
11
-
-
34047181147
-
Drug Insight: Role of the androgen receptor in the development and progression of prostate cancer
-
Taplin M E, Drug Insight: role of the androgen receptor in the development and progression of prostate cancer, Nat Clin Pract Oncol, 4 (2007) 236.
-
(2007)
Nat Clin Pract Oncol
, vol.4
, pp. 236
-
-
Taplin, M.E.1
-
12
-
-
70349395222
-
Anti-androgens and androgen-depleting therapies in prostate cancer: New agents for an established target
-
Chen Y, Clegg N J & Scher H I, Anti-androgens and androgen-depleting therapies in prostate cancer: new agents for an established target, Lancet Oncol, 10 (2009) 981.
-
(2009)
Lancet Oncol
, vol.10
, pp. 981
-
-
Chen, Y.1
Clegg, N.J.2
Scher, H.I.3
-
13
-
-
48549089747
-
Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance
-
Dehm S M, Schmidt L J, Heemers H V, Vessella R L & Tindall D J, Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance, Cancer Res, 68 (2008) 5469.
-
(2008)
Cancer Res
, vol.68
, pp. 5469
-
-
Dehm, S.M.1
Schmidt, L.J.2
Heemers, H.V.3
Vessella, R.L.4
Tindall, D.J.5
-
14
-
-
65549168746
-
A novel androgen receptor splice variant is upregulated during prostate cancer progression and promotes androgen depletion-resistant growth
-
Guo Z, Yang X, Sun F, Jiang R, Linn D E, Chen H, Kong X, Melamed J, Tepper C G, Kung H, Brodie A M H, Edwards J & Qui Y, A novel androgen receptor splice variant is upregulated during prostate cancer progression and promotes androgen depletion-resistant growth, Cancer Res, 69 (2009) 2305.
-
(2009)
Cancer Res
, vol.69
, pp. 2305
-
-
Guo, Z.1
Yang, X.2
Sun, F.3
Jiang, R.4
Linn, D.E.5
Chen, H.6
Kong, X.7
Melamed, J.8
Tepper, C.G.9
Kung, H.10
Brodie, A.M.H.11
Edwards, J.12
Qui, Y.13
-
15
-
-
58249110391
-
Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer
-
Hu R, Dunn T A, Wei S, Isharwal S, Veltri R W, Humphreys E, Han M, Partin A W, Vessella R L, Isaacs W B, Bova G S & Luo J, Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer, Cancer Res, 69 (2009) 16.
-
(2009)
Cancer Res
, vol.69
, pp. 16
-
-
Hu, R.1
Dunn, T.A.2
Wei, S.3
Isharwal, S.4
Veltri, R.W.5
Humphreys, E.6
Han, M.7
Partin, A.W.8
Vessella, R.L.9
Isaacs, W.B.10
Bova, G.S.11
Luo, J.12
-
16
-
-
77955296562
-
Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant
-
Sun S, Sprenger C C, Vessella R L, Haugk K, Soriano K, Mostaghel E A, Page S T, Coleman I M, Nguyen H M, Sun H, Nelson P S & Plymate S R, Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant, J Clin Invest, 120 (2010) 2715.
-
(2010)
J Clin Invest
, vol.120
, pp. 2715
-
-
Sun, S.1
Sprenger, C.C.2
Vessella, R.L.3
Haugk, K.4
Soriano, K.5
Mostaghel, E.A.6
Page, S.T.7
Coleman, I.M.8
Nguyen, H.M.9
Sun, H.10
Nelson, P.S.11
Plymate, S.R.12
-
17
-
-
74049109753
-
Identification of novel truncated androgen receptor (AR) mutants including unreported pre-mRNA splicing variants in the 22Rv1 hormone-refractory prostate cancer (PCa) cell line
-
Marcias G, Erdmann E, Lapouge G, Siebert C, Barthélémy P, Duclos B, Bergerat J P, Céraline J & Kurtz J E, Identification of novel truncated androgen receptor (AR) mutants including unreported pre-mRNA splicing variants in the 22Rv1 hormone-refractory prostate cancer (PCa) cell line, Hum Mutat, 31 (2010) 74.
-
(2010)
Hum Mutat
, vol.31
, pp. 74
-
-
Marcias, G.1
Erdmann, E.2
Lapouge, G.3
Siebert, C.4
Barthélémy, P.5
Duclos, B.6
Bergerat, J.P.7
Céraline, J.8
Kurtz, J.E.9
-
18
-
-
78049280194
-
Constitutively active androgen receptor splice variants expressed in castrationresistant prostate cancer require full-length androgen receptor
-
Watson P A, Chen Y F, Balbas M D, Wongvipat J, Socci N D, Viale A, Kim K & Sawyers C L, Constitutively active androgen receptor splice variants expressed in castrationresistant prostate cancer require full-length androgen receptor, Proc Natl Acad Sci U S A, 107 (2010) 16759.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 16759
-
-
Watson, P.A.1
Chen, Y.F.2
Balbas, M.D.3
Wongvipat, J.4
Socci, N.D.5
Viale, A.6
Kim, K.7
Sawyers, C.L.8
-
19
-
-
79955093434
-
Genetic therapies for RNA mis-splicing diseases
-
Hammond S M & Wood M J A, Genetic therapies for RNA mis-splicing diseases. Trends Genet, 27 (2011) 196.
-
(2011)
Trends Genet
, vol.27
, pp. 196
-
-
Hammond, S.M.1
Wood, M.J.A.2
-
20
-
-
78650916689
-
The status of exon skipping as a therapeutic approach to Duchenne muscular dystrophy
-
Lu Q, Yokota T, Takeda S, Garcia L, Muntoni F & Partridge T, The status of exon skipping as a therapeutic approach to Duchenne muscular dystrophy, Mol Ther, 19 (2011) 9.
-
(2011)
Mol Ther
, vol.19
, pp. 9
-
-
Lu, Q.1
Yokota, T.2
Takeda, S.3
Garcia, L.4
Muntoni, F.5
Partridge, T.6
-
21
-
-
34748906143
-
Antisense-mediated exon skipping: A versatile tool with therapeutic and research applications
-
Aartsma-Rus A & van Ommen G B, Antisense-mediated exon skipping: A versatile tool with therapeutic and research applications. RNA, 13 (2007) 1609.
-
(2007)
RNA
, vol.13
, pp. 1609
-
-
Aartsma-Rus, A.1
van Ommen, G.B.2
-
22
-
-
70349451258
-
Development of antisensemediated exon skipping as a treatment for Duchenne muscular dystrophy
-
Heemskerk H, de Winter C L, van Ommen G J, van Deutekom J C & Aartsma-Rus A, Development of antisensemediated exon skipping as a treatment for Duchenne muscular dystrophy, Ann NY Acad Sci, 1175 (2009) 71.
-
(2009)
Ann NY Acad Sci
, vol.1175
, pp. 71
-
-
Heemskerk, H.1
de Winter, C.L.2
van Ommen, G.J.3
van Deutekom, J.C.4
Aartsma-Rus, A.5
-
23
-
-
79955158683
-
Systemic administration of PRO051 in Duchenne's muscular dystrophy
-
Goemans N M, Tulinius M, van den Akker J T, Burm B E, Ekhart P F, Heuvelmans N, Holling T, Janson A A, Platenburg G J, Sipkens J A, Sitsen J M, Aartsma-Rus A, van Ommen G J, Buyse G, Darin N, Ver-schuuren J J, Campion G V, de Kimpe S J & van Deutekom J C, Systemic administration of PRO051 in Duchenne's muscular dystrophy, N Engl J Med, 364 (2011) 1513.
-
(2011)
N Engl J Med
, vol.364
, pp. 1513
-
-
Goemans, N.M.1
Tulinius, M.2
van den Akker, J.T.3
Burm, B.E.4
Ekhart, P.F.5
Heuvelmans, N.6
Holling, T.7
Janson, A.A.8
Platenburg, G.J.9
Sipkens, J.A.10
Sitsen, J.M.11
Aartsma-Rus, A.12
van Ommen, G.J.13
Buyse, G.14
Darin, N.15
Ver-Schuuren, J.J.16
Campion, G.V.17
de Kimpe, S.J.18
van Deutekom, J.C.19
-
24
-
-
69949107887
-
Local restoration of dystrophin expression with the morpholino oligomer AVI-4658 in Duchenne muscular dystrophy: A single-blind, placebo-controlled, dose-escalation, proof-of-concept study
-
Kinali M, Arechavala-Gomeza V, Feng L, Cirak S, Hunt D, Adkin C, Guglieri M, Ashton E, Abbs S, Nihoyannopoulos P, Garralda M E, Rutherford M, McCulley C, Popplewell L, Graham I R, Dickson G, Wood M J, Wells D J, Wilton S D, Kole R, Straub V, Bushby K, Sewry C, Morgan J E & Muntoni F, Local restoration of dystrophin expression with the morpholino oligomer AVI-4658 in Duchenne muscular dystrophy: a single-blind, placebo-controlled, dose-escalation, proof-of-concept study, Lancet Neurol, 8 (2009) 918.
-
(2009)
Lancet Neurol
, vol.8
, pp. 918
-
-
Kinali, M.1
Arechavala-Gomeza, V.2
Feng, L.3
Cirak, S.4
Hunt, D.5
Adkin, C.6
Guglieri, M.7
Ashton, E.8
Abbs, S.9
Nihoyannopoulos, P.10
Garralda, M.E.11
Rutherford, M.12
McCulley, C.13
Popplewell, L.14
Graham, I.R.15
Dickson, G.16
Wood, M.J.17
Wells, D.J.18
Wilton, S.D.19
Kole, R.20
Straub, V.21
Bushby, K.22
Sewry, C.23
Morgan, J.E.24
Muntoni, F.25
more..
-
25
-
-
79951821796
-
Antisense Inhibition of Survivin Expression as a Cancer Therapeutic
-
Carrasco R A, Stamm N B, Marcusson E, Sandusky G, Iversen P & Patel B K R, Antisense Inhibition of Survivin Expression as a Cancer Therapeutic, Mol Cancer Ther, 10 (2011) 221.
-
(2011)
Mol Cancer Ther
, vol.10
, pp. 221
-
-
Carrasco, R.A.1
Stamm, N.B.2
Marcusson, E.3
Sandusky, G.4
Iversen, P.5
Patel, B.K.R.6
-
26
-
-
0035496913
-
Regulation of the inhibitor-ofapoptosis family member survivin in normal cord blood and bone marrow CD34(+) cells by hematopoietic growth factors: Implication of survivin expression in normal hematopoiesis
-
Fukuda S & Pelus L M, Regulation of the inhibitor-ofapoptosis family member survivin in normal cord blood and bone marrow CD34(+) cells by hematopoietic growth factors: implication of survivin expression in normal hematopoiesis, Blood, 98 (2001) 2091.
-
(2001)
Blood
, vol.98
, pp. 2091
-
-
Fukuda, S.1
Pelus, L.M.2
-
27
-
-
78650440393
-
Anti-tumor activity of splice-switching oligonucleotides
-
Bauman J A, Li S D, Yang A, Huang L, Kole R, Anti-tumor activity of splice-switching oligonucleotides, Nucl Acids Res, 38 (2010) 8348.
-
(2010)
Nucl Acids Res
, vol.38
, pp. 8348
-
-
Bauman, J.A.1
Li, S.D.2
Yang, A.3
Huang, L.4
Kole, R.5
-
28
-
-
79952772097
-
Intragenic rearrangement and altered RNA splicing of the androgen receptor in a cell-based model of prostate cancer progression
-
Li Y, Alsagabi M, Fan D, Bova G S, Tewfik A H, Dehm S M, Intragenic rearrangement and altered RNA splicing of the androgen receptor in a cell-based model of prostate cancer progression, Cancer Res, 71 (2011) 2108.
-
(2011)
Cancer Res
, vol.71
, pp. 2108
-
-
Li, Y.1
Alsagabi, M.2
Fan, D.3
Bova, G.S.4
Tewfik, A.H.5
Dehm, S.M.6
-
29
-
-
77958118514
-
Pharmacological targeting of constitutively active truncated androgen receptor by nigericin and suppression of hormone-refractory prostate cancer cell growth
-
Mashima T, Okabe S & Seimiya H, Pharmacological targeting of constitutively active truncated androgen receptor by nigericin and suppression of hormone-refractory prostate cancer cell growth, Mol Pharmacol, 78 (2010) 846.
-
(2010)
Mol Pharmacol
, vol.78
, pp. 846
-
-
Mashima, T.1
Okabe, S.2
Seimiya, H.3
|