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Volumn 38, Issue 22, 2010, Pages 8348-8356

Anti-tumor activity of splice-switching oligonucleotides

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; MESSENGER RNA PRECURSOR; OLIGONUCLEOTIDE; PROTEIN BCL X; PROTEIN BCL XL; PROTEIN BCL XS; SOLID LIPID NANOPARTICLE; SPLICE SWITCHING OLIGONUCLEOTIDE; UNCLASSIFIED DRUG;

EID: 78650440393     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkq731     Document Type: Article
Times cited : (118)

References (43)
  • 2
    • 15544379277 scopus 로고    scopus 로고
    • Are splicing mutations the most frequent cause of hereditary disease?
    • Lopez-Bigas, N., Audit, B., Ouzounis, C., Parra, G. and Guigo, R. (2005) Are splicing mutations the most frequent cause of hereditary disease? FEBS Lett., 579, 1900-1903.
    • (2005) FEBS Lett. , vol.579 , pp. 1900-1903
    • Lopez-Bigas, N.1    Audit, B.2    Ouzounis, C.3    Parra, G.4    Guigo, R.5
  • 3
    • 60149093432 scopus 로고    scopus 로고
    • RNA and disease
    • Cooper, T.A., Wan, L. and Dreyfuss, G. (2009) RNA and disease. Cell, 136, 777-793.
    • (2009) Cell , vol.136 , pp. 777-793
    • Cooper, T.A.1    Wan, L.2    Dreyfuss, G.3
  • 4
    • 0027284424 scopus 로고
    • Restoration of correct splicing in thalassemic pre-mRNA by antisense oligonucleotides
    • Dominski, Z. and Kole, R. (1993) Restoration of correct splicing in thalassemic pre-mRNA by antisense oligonucleotides. Proc. Natl Acad. Sci. USA, 90, 8673-8677.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 8673-8677
    • Dominski, Z.1    Kole, R.2
  • 5
    • 0029803547 scopus 로고    scopus 로고
    • Repair of thalassemic human beta-globin mRNA in mammalian cells by antisense oligonucleotides
    • Sierakowska, H., Sambade, M.J., Agrawal, S. and Kole, R. (1996) Repair of thalassemic human beta-globin mRNA in mammalian cells by antisense oligonucleotides. Proc. Natl Acad. Sci. USA, 93, 12840-12844.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 12840-12844
    • Sierakowska, H.1    Sambade, M.J.2    Agrawal, S.3    Kole, R.4
  • 8
    • 67249122712 scopus 로고    scopus 로고
    • Biological barriers to therapy with antisense and siRNA oligonucleotides
    • Juliano, R.L., Bauman, J., Kang, H. and Ming, X. (2009) Biological barriers to therapy with antisense and siRNA oligonucleotides. Mol. Pharm., 6, 686-695.
    • (2009) Mol. Pharm. , vol.6 , pp. 686-695
    • Juliano, R.L.1    Bauman, J.2    Kang, H.3    Ming, X.4
  • 9
    • 45749096229 scopus 로고    scopus 로고
    • An endogenous TNF-alpha antagonist induced by splice-switching oligonucleotides reduces inflammation in hepatitis and arthritis mouse models
    • Graziewicz, M.A., Tarrant, T.K., Buckley, B., Roberts, J., Fulton, L., Hansen, H., Orum, H., Kole, R. and Sazani, P. (2008) An endogenous TNF-alpha antagonist induced by splice-switching oligonucleotides reduces inflammation in hepatitis and arthritis mouse models. Mol. Ther., 16, 1316-1322.
    • (2008) Mol. Ther. , vol.16 , pp. 1316-1322
    • Graziewicz, M.A.1    Tarrant, T.K.2    Buckley, B.3    Roberts, J.4    Fulton, L.5    Hansen, H.6    Orum, H.7    Kole, R.8    Sazani, P.9
  • 14
    • 67349244344 scopus 로고    scopus 로고
    • Cationic PMMA nanoparticles bind and deliver antisense oligoribonucleotides allowing restoration of dystrophin expression in the mdx mouse
    • Rimessi, P., Sabatelli, P., Fabris, M., Braghetta, P., Bassi, E., Spitali, P., Vattemi, G., Tomelleri, G., Mari, L., Perrone, D. et al. (2009) Cationic PMMA nanoparticles bind and deliver antisense oligoribonucleotides allowing restoration of dystrophin expression in the mdx mouse. Mol. Ther., 17, 820-827.
    • (2009) Mol. Ther. , vol.17 , pp. 820-827
    • Rimessi, P.1    Sabatelli, P.2    Fabris, M.3    Braghetta, P.4    Bassi, E.5    Spitali, P.6    Vattemi, G.7    Tomelleri, G.8    Mari, L.9    Perrone, D.10
  • 15
    • 61349157969 scopus 로고    scopus 로고
    • Therapeutic potential of splice-switching oligonucleotides
    • Bauman, J., Jearawiriyapaisarn, N. and Kole, R. (2009) Therapeutic potential of splice-switching oligonucleotides. Oligonucleotides, 19, 1-14.
    • (2009) Oligonucleotides , vol.19 , pp. 1-14
    • Bauman, J.1    Jearawiriyapaisarn, N.2    Kole, R.3
  • 17
    • 69949107887 scopus 로고    scopus 로고
    • Local restoration of dystrophin expression with the morpholino oligomer AVI-4658 in Duchenne muscular dystrophy: A single-blind, placebo-controlled, dose-escalation, proof-of-concept study
    • Kinali, M., Arechavala-Gomeza, V., Feng, L., Cirak, S., Hunt, D., Adkin, C., Guglieri, M., Ashton, E., Abbs, S., Nihoyannopoulos, P. et al. (2009) Local restoration of dystrophin expression with the morpholino oligomer AVI-4658 in Duchenne muscular dystrophy: a single-blind, placebo-controlled, dose-escalation, proof-of-concept study. Lancet Neurol., 8, 918-928.
    • (2009) Lancet Neurol. , vol.8 , pp. 918-928
    • Kinali, M.1    Arechavala-Gomeza, V.2    Feng, L.3    Cirak, S.4    Hunt, D.5    Adkin, C.6    Guglieri, M.7    Ashton, E.8    Abbs, S.9    Nihoyannopoulos, P.10
  • 19
    • 0034327411 scopus 로고    scopus 로고
    • An informatics approach identifying markers of chemosensitivity in human cancer cell lines
    • Amundson, S.A., Myers, T.G., Scudiero, D., Kitada, S., Reed, J.C. and Fornace, A.J. Jr (2000) An informatics approach identifying markers of chemosensitivity in human cancer cell lines. Cancer Res., 60, 6101-6110.
    • (2000) Cancer Res. , vol.60 , pp. 6101-6110
    • Amundson, S.A.1    Myers, T.G.2    Scudiero, D.3    Kitada, S.4    Reed, J.C.5    Fornace Jr., A.J.6
  • 20
    • 0034877148 scopus 로고    scopus 로고
    • Bcl-x(S) can form homodimers and heterodimers and its apoptotic activity requires localization of Bcl-x(S) to the mitochondria and its BH3 and loop domains
    • Lindenboim, L., Borner, C. and Stein, R. (2001) Bcl-x(S) can form homodimers and heterodimers and its apoptotic activity requires localization of Bcl-x(S) to the mitochondria and its BH3 and loop domains. Cell Death Differ., 8, 933-942.
    • (2001) Cell Death Differ. , vol.8 , pp. 933-942
    • Lindenboim, L.1    Borner, C.2    Stein, R.3
  • 21
    • 0029874986 scopus 로고    scopus 로고
    • Bcl-x(S) anatagonizes the protective effects of Bcl-x(L)
    • Minn, A.J., Boise, L.H. and Thompson, C.B. (1996) Bcl-x(S) anatagonizes the protective effects of Bcl-x(L). J. Biol. Chem., 271, 6306-6312.
    • (1996) J. Biol. Chem. , vol.271 , pp. 6306-6312
    • Minn, A.J.1    Boise, L.H.2    Thompson, C.B.3
  • 22
    • 0035844238 scopus 로고    scopus 로고
    • Modification of alternative splicing of Bcl-x pre-mRNA in prostate and breast cancer cells. analysis of apoptosis and cell death
    • Mercatante, D.R., Bortner, C.D., Cidlowski, J.A. and Kole, R. (2001) Modification of alternative splicing of Bcl-x pre-mRNA in prostate and breast cancer cells. analysis of apoptosis and cell death. J. Biol. Chem., 276, 16411-16417.
    • (2001) J. Biol. Chem. , vol.276 , pp. 16411-16417
    • Mercatante, D.R.1    Bortner, C.D.2    Cidlowski, J.A.3    Kole, R.4
  • 23
    • 0345829926 scopus 로고    scopus 로고
    • Cellular response to an antisense-mediated shift of Bcl-x pre-mRNA splicing and antineoplastic agents
    • Mercatante, D.R., Mohler, J.L. and Kole, R. (2002) Cellular response to an antisense-mediated shift of Bcl-x pre-mRNA splicing and antineoplastic agents. J. Biol. Chem., 277, 49374-49382.
    • (2002) J. Biol. Chem. , vol.277 , pp. 49374-49382
    • Mercatante, D.R.1    Mohler, J.L.2    Kole, R.3
  • 24
    • 0003826861 scopus 로고    scopus 로고
    • Induction of endogenous Bcl-xS through the control of Bcl-x pre-mRNA splicing by antisense oligonucleotides
    • Taylor, J.K., Zhang, Q.Q., Wyatt, J.R. and Dean, N.M. (1999) Induction of endogenous Bcl-xS through the control of Bcl-x pre-mRNA splicing by antisense oligonucleotides. Nat. Biotechnol., 17, 1097-1100.
    • (1999) Nat. Biotechnol. , vol.17 , pp. 1097-1100
    • Taylor, J.K.1    Zhang, Q.Q.2    Wyatt, J.R.3    Dean, N.M.4
  • 25
    • 33947598446 scopus 로고    scopus 로고
    • Mcl-1, Bcl-XL and Stat3 expression are associated with progression of melanoma whereas Bcl-2, AP-2 and MITF levels decrease during progression of melanoma
    • Zhuang, L., Lee, C.S., Scolyer, R.A., McCarthy, S.W., Zhang, X.D., Thompson, J.F. and Hersey, P. (2007) Mcl-1, Bcl-XL and Stat3 expression are associated with progression of melanoma whereas Bcl-2, AP-2 and MITF levels decrease during progression of melanoma. Mod. Pathol., 20, 416-426.
    • (2007) Mod. Pathol. , vol.20 , pp. 416-426
    • Zhuang, L.1    Lee, C.S.2    Scolyer, R.A.3    McCarthy, S.W.4    Zhang, X.D.5    Thompson, J.F.6    Hersey, P.7
  • 27
    • 33845679807 scopus 로고    scopus 로고
    • Surface-modified LPD nanoparticles for tumor targeting
    • Li, S.D. and Huang, L. (2006) Surface-modified LPD nanoparticles for tumor targeting. Ann. NY Acad. Sci., 1082, 1-8.
    • (2006) Ann. NY Acad. Sci. , vol.1082 , pp. 1-8
    • Li, S.D.1    Huang, L.2
  • 28
    • 33750417183 scopus 로고    scopus 로고
    • Targeted delivery of antisense oligodeoxynucleotide and small interference RNA into lung cancer cells
    • Li, S.D. and Huang, L. (2006) Targeted delivery of antisense oligodeoxynucleotide and small interference RNA into lung cancer cells. Mol. Pharm., 3, 579-588.
    • (2006) Mol. Pharm. , vol.3 , pp. 579-588
    • Li, S.D.1    Huang, L.2
  • 29
    • 37549004351 scopus 로고    scopus 로고
    • Tumor-targeted delivery of siRNA by self-assembled nanoparticles
    • Li, S.D., Chen, Y.C., Hackett, M.J. and Huang, L. (2008) Tumor-targeted delivery of siRNA by self-assembled nanoparticles. Mol. Ther., 16, 163-169.
    • (2008) Mol. Ther. , vol.16 , pp. 163-169
    • Li, S.D.1    Chen, Y.C.2    Hackett, M.J.3    Huang, L.4
  • 30
    • 42549142820 scopus 로고    scopus 로고
    • Efficient oncogene silencing and metastasis inhibition via systemic delivery of siRNA
    • Li, S.D., Chono, S. and Huang, L. (2008) Efficient oncogene silencing and metastasis inhibition via systemic delivery of siRNA. Mol. Ther., 16, 942-946.
    • (2008) Mol. Ther. , vol.16 , pp. 942-946
    • Li, S.D.1    Chono, S.2    Huang, L.3
  • 31
    • 38549103632 scopus 로고    scopus 로고
    • Efficient gene silencing in metastatic tumor by siRNA formulated in surface-modified nanoparticles
    • Li, S.D., Chono, S. and Huang, L. (2008) Efficient gene silencing in metastatic tumor by siRNA formulated in surface-modified nanoparticles. J. Control Release, 126, 77-84.
    • (2008) J. Control Release , vol.126 , pp. 77-84
    • Li, S.D.1    Chono, S.2    Huang, L.3
  • 32
    • 0029032044 scopus 로고
    • Sigma receptors are expressed in human non-small cell lung carcinoma
    • John, C.S., Bowen, W.D., Varma, V.M., McAfee, J.G. and Moody, T.W. (1995) Sigma receptors are expressed in human non-small cell lung carcinoma. Life Sci., 56, 2385-2392.
    • (1995) Life Sci. , vol.56 , pp. 2385-2392
    • John, C.S.1    Bowen, W.D.2    Varma, V.M.3    McAfee, J.G.4    Moody, T.W.5
  • 33
    • 0028795145 scopus 로고
    • Sigma-1 and sigma-2 receptors are expressed in a wide variety of human and rodent tumor cell lines
    • Vilner, B.J., John, C.S. and Bowen, W.D. (1995) Sigma-1 and sigma-2 receptors are expressed in a wide variety of human and rodent tumor cell lines. Cancer Res., 55, 408-413.
    • (1995) Cancer Res. , vol.55 , pp. 408-413
    • Vilner, B.J.1    John, C.S.2    Bowen, W.D.3
  • 34
    • 7044231886 scopus 로고    scopus 로고
    • Anisamide-targeted stealth liposomes: A potent carrier for targeting doxorubicin to human prostate cancer cells
    • Banerjee, R., Tyagi, P., Li, S. and Huang, L. (2004) Anisamide-targeted stealth liposomes: a potent carrier for targeting doxorubicin to human prostate cancer cells. Int. J. Cancer, 112, 693-700.
    • (2004) Int. J. Cancer , vol.112 , pp. 693-700
    • Banerjee, R.1    Tyagi, P.2    Li, S.3    Huang, L.4
  • 37
    • 70349542520 scopus 로고    scopus 로고
    • Nanoparticles evading the reticuloendothelial system: Role of the supported bilayer
    • Li, S.D. and Huang, L. (2009) Nanoparticles evading the reticuloendothelial system: role of the supported bilayer. Biochim. Biophys. Acta, 1788, 2259-2266.
    • (2009) Biochim. Biophys. Acta , vol.1788 , pp. 2259-2266
    • Li, S.D.1    Huang, L.2
  • 38
    • 52049121804 scopus 로고    scopus 로고
    • An efficient and low immunostimulatory nanoparticle formulation for systemic siRNA delivery to the tumor
    • Chono, S., Li, S.D., Conwell, C.C. and Huang, L. (2008) An efficient and low immunostimulatory nanoparticle formulation for systemic siRNA delivery to the tumor. J. Control Release, 131, 64-69.
    • (2008) J. Control Release , vol.131 , pp. 64-69
    • Chono, S.1    Li, S.D.2    Conwell, C.C.3    Huang, L.4
  • 39
    • 51049104302 scopus 로고    scopus 로고
    • Pharmacokinetics and biodistribution of nanoparticles
    • Li, S.D. and Huang, L. (2008) Pharmacokinetics and biodistribution of nanoparticles. Mol. Pharm., 5, 496-504.
    • (2008) Mol. Pharm. , vol.5 , pp. 496-504
    • Li, S.D.1    Huang, L.2
  • 40
    • 58149465910 scopus 로고    scopus 로고
    • Modification of HER2 pre-mRNA alternative splicing and its effects on breast cancer cells
    • Wan, J., Sazani, P. and Kole, R. (2009) Modification of HER2 pre-mRNA alternative splicing and its effects on breast cancer cells. Int. J. Cancer, 124, 772-777.
    • (2009) Int. J. Cancer , vol.124 , pp. 772-777
    • Wan, J.1    Sazani, P.2    Kole, R.3
  • 42
    • 68149112387 scopus 로고    scopus 로고
    • Mimicking the BH3 domain to kill cancer cells
    • Chonghaile, T.N. and Letai, A. (2008) Mimicking the BH3 domain to kill cancer cells. Oncogene, 27(Suppl 1), S149-S157.
    • (2008) Oncogene , vol.27 , Issue.SUPPL. 1
    • Chonghaile, T.N.1    Letai, A.2


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