Na +/K +-ATPase is present in scrapie-associated fibrils, modulates PrP misfolding in vitro and links PrP function and dysfunction

PLoS ONE

Volumn 6, Issue 11, 2011, Pages

  Graham, James F ^a   Kurian, Dominic ^b   Agarwal, Sonya ^a   Toovey, Lorna ^a   Hunt, Lawrence ^b   Kirby, Louise ^a   Pinheiro, Teresa J T ^c   Banner, Steven J ^a   Gill, Andrew C ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b INSTITUTE FOR ANIMAL HEALTH   (United Kingdom)

^c UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); RECOMBINANT PROTEIN; PRION PROTEIN;

ALPHA CHAIN; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME LOCALIZATION; FUNCTIONAL PROTEOMICS; IN VITRO STUDY; MOLECULAR PATHOLOGY; MOUSE; NEUROFILAMENT; NEUROPATHOLOGY; NONHUMAN; PROTEIN ANALYSIS; PROTEIN DEFECT; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN MISFOLDING; PROTEIN PURIFICATION; SCRAPIE; SCRAPIE ASSOCIATED FIBRIL; TISSUE SPECIFICITY; VIRUS STRAIN; WILD TYPE; ANIMAL; ENZYMOLOGY; LIQUID CHROMATOGRAPHY; METABOLISM; POLYACRYLAMIDE GEL ELECTROPHORESIS; REPRODUCIBILITY; SPECIES DIFFERENCE; TANDEM MASS SPECTROMETRY; WESTERN BLOTTING;

MUS;

ANIMALS; BLOTTING, WESTERN; CHROMATOGRAPHY, LIQUID; ELECTROPHORESIS, POLYACRYLAMIDE GEL; MICE; PROTEIN FOLDING; PRPSC PROTEINS; REPRODUCIBILITY OF RESULTS; SCRAPIE; SODIUM-POTASSIUM-EXCHANGING ATPASE; SPECIES SPECIFICITY; TANDEM MASS SPECTROMETRY;

EID: 80355123638     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0026813     Document Type: Article

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