Neuronal low-density lipoprotein receptor-related protein 1 binds and endocytoses prion fibrils via receptor cluster 4

Journal of Cell Science

Volumn 123, Issue 2, 2010, Pages 246-255

  Jen, Angela ^a   Parkyn, Celia J ^a   Mootoosamy, Roy C ^a   Ford, Melanie J ^a   Warley, Alice ^a   Liu, Qiang ^b   Bu, Guojun ^b   Baskakov, Ilia V ^c   Moestrup, Søren ^d   McGuinness, Lindsay ^e   Emptage, Nigel ^e   Morris, Roger J ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b ST LOUIS CHILDREN S HOSPITAL   (United States)

^c UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

^d AARHUS UNIVERSITY   (Denmark)

^e UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Endocytosis; LRP1; Lysosome; Neuron; Prion protein

Indexed keywords

LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; PRION PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL FATE; CELL FUNCTION; CELL SURFACE; CELL VIABILITY; CONTROLLED STUDY; ENDOCYTOSIS; INTERNALIZATION; LYSOSOME; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RAT; SCRAPIE; SENSORY NERVE CELL;

ANIMALS; CELLS, CULTURED; ENDOCYTOSIS; ENDOSOMES; LIGANDS; LYSOSOMES; MICE; MICE, INBRED C57BL; PEPTIDE HYDROLASES; PRIONS; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PRPC PROTEINS; PRPSC PROTEINS; RECEPTORS, LDL; SENSORY RECEPTOR CELLS; TUMOR SUPPRESSOR PROTEINS;

EID: 73849129337     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.058099     Document Type: Article

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