Is rat an appropriate animal model to study the involvement of d -serine catabolism in schizophrenia? insights from characterization of d -amino acid oxidase

FEBS Journal

Volumn 278, Issue 22, 2011, Pages 4362-4373

  Frattini, Luca F ^a   Piubelli, Luciano ^a   Sacchi, Silvia ^a   Molla, Gianluca ^a   Pollegioni, Loredano ^a  

^a UNIVERSITY OF INSUBRIA   (Italy)

Author keywords

d serine; drug design; flavoproteins; ligand binding; schizophrenia

Indexed keywords

DEXTRO AMINO ACID OXIDASE; DEXTRO SERINE; RECOMBINANT ENZYME;

AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING KINETICS; BINDING SITE; CANCER CELL CULTURE; COMPLEX FORMATION; CONTROLLED STUDY; DEGRADATION KINETICS; DISEASE MODEL; ENZYME BINDING; ENZYME SPECIFICITY; ENZYME SUBSTRATE; ESCHERICHIA COLI; EXPERIMENTAL RAT; GLIOBLASTOMA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; INTROSPECTION; MOLECULAR PATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RAT; SCHIZOPHRENIA; SPECIES COMPARISON; STEADY STATE; WESTERN BLOTTING;

ANIMALS; CARRIER PROTEINS; D-AMINO-ACID OXIDASE; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; FLAVIN-ADENINE DINUCLEOTIDE; GLIOBLASTOMA; HUMANS; PROTEIN BINDING; PROTEIN CONFORMATION; RATS; RECOMBINANT PROTEINS; SCHIZOPHRENIA; SERINE; SUBSTRATE SPECIFICITY; TUMOR CELLS, CULTURED;

ANIMALIA; ESCHERICHIA COLI; MAMMALIA; RATTUS; RODENTIA;

EID: 80255135490     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2011.08354.x     Document Type: Article

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