Characterization of currently marketed heparin products: Analysis of molecular weight and heparinase-I digest patterns

Analytical and Bioanalytical Chemistry

Volumn 401, Issue 8, 2011, Pages 2445-2454

  Sommers, Cynthia D ^a   Ye, Hongping ^a   Kolinski, Richard E ^a   Nasr, Moheb ^a   Buhse, Lucinda F ^a   Al Hakim, Ali ^a   Keire, David A ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Heparin sodium; Low molecular weight heparin; Multi angle laser light scattering; Polyacrylamide gel electrophoresis; Size exclusion chromatography

Indexed keywords

HEPARIN SODIUM; LOW-MOLECULAR WEIGHT HEPARINS; MULTIANGLE LASER LIGHT SCATTERING; POLYACRYLAMIDE GEL ELECTROPHORESIS; SIZE EXCLUSION;

ELECTROPHORESIS; GEL PERMEATION CHROMATOGRAPHY; GELS; LIGHT SCATTERING; MOLECULAR WEIGHT; POLYDISPERSITY; RATING; REFRACTION; REFRACTIVE INDEX; SIZE EXCLUSION CHROMATOGRAPHY; SODIUM; WATER CONTENT;

POLYSACCHARIDES;

ANTICOAGULANT AGENT; HEPARIN; HEPARIN LYASE; LOW MOLECULAR WEIGHT HEPARIN;

ARTICLE; CHEMISTRY; EVALUATION; GEL CHROMATOGRAPHY; LIGHT; METABOLISM; METHODOLOGY; MOLECULAR WEIGHT; POLYACRYLAMIDE GEL ELECTROPHORESIS; RADIATION SCATTERING; REFRACTOMETRY;

ANTICOAGULANTS; CHROMATOGRAPHY, GEL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HEPARIN; HEPARIN LYASE; HEPARIN, LOW-MOLECULAR-WEIGHT; LIGHT; MOLECULAR WEIGHT; REFRACTOMETRY; SCATTERING, RADIATION;

EID: 80255129278     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-011-5362-z     Document Type: Article

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