Development and qualification of a size exclusion chromatography coupled with multiangle light scattering method for molecular weight determination of unfractionated heparin

Analytical and Bioanalytical Chemistry

Volumn 399, Issue 2, 2011, Pages 717-725

  Beirne, John ^a   Truchan, Hilary ^b   Rao, Lin ^a  

^a Scientific Protein Laboratories LLC   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

dn dc; Heparin; Molecular weight and molecular weight distribution; SEC MALS; Second virial coefficient A 2

Indexed keywords

ANGULAR DEPENDENCE; CALIBRATION METHOD; DN/DC; HEPARIN; MOLECULAR WEIGHT DETERMINATION; MULTI-ANGLE LIGHT SCATTERINGS; SCATTERED LIGHT; SEC/MALS; SECOND VIRIAL COEFFICIENTS; UNFRACTIONATED HEPARINS;

CALIBRATION; LIGHT SCATTERING; MOLECULAR WEIGHT DISTRIBUTION; POLYSACCHARIDES; REFRACTION; SCATTERING;

SIZE EXCLUSION CHROMATOGRAPHY;

ANTICOAGULANT AGENT; HEPARIN;

ARTICLE; CHEMISTRY; DRUG CONTAMINATION; EVALUATION; GEL CHROMATOGRAPHY; LIGHT; METHODOLOGY; MOLECULAR WEIGHT; RADIATION SCATTERING; SENSITIVITY AND SPECIFICITY;

ANTICOAGULANTS; CHROMATOGRAPHY, GEL; DRUG CONTAMINATION; HEPARIN; LIGHT; MOLECULAR WEIGHT; SCATTERING, RADIATION; SENSITIVITY AND SPECIFICITY;

EID: 79251604174     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-010-4187-5     Document Type: Article

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