-
1
-
-
33646740974
-
Antagonists to Human and Mouse Vascular Endothelial Growth Factor Receptor 2 Generated by Directed Protein Evolution In Vitro
-
DOI 10.1016/j.chembiol.2005.12.009, PII S1074552106000081
-
EV Getmanova Y Chen L Bloom J Gokemeijer S Shamah V Warikoo, et al. 2006 Antagonists to human and mouse vascular endothelial growth factor receptor 2 generated by directed protein evolution in vitro Chem Biol 13 549 556 16720276 10.1016/j.chembiol.2005.12.009 1:CAS:528:DC%2BD28XkvVCqtb8%3D (Pubitemid 43744513)
-
(2006)
Chemistry and Biology
, vol.13
, Issue.5
, pp. 549-556
-
-
Getmanova, E.V.1
Chen, Y.2
Bloom, L.3
Gokemeijer, J.4
Shamah, S.5
Warikoo, V.6
Wang, J.7
Ling, V.8
Sun, L.9
-
2
-
-
70350521639
-
Generation of tumour-necrosis-factor-alpha-specific affibody molecules capable of blocking receptor binding in vitro
-
19545237 10.1042/BA20090085 1:CAS:528:DC%2BD1MXpvF2iu7o%3D
-
A Jonsson H Wållberg N Herne S Ståhl FY Frejd 2009 Generation of tumour-necrosis-factor-alpha-specific affibody molecules capable of blocking receptor binding in vitro Biotechnol Appl Biochem 54 93 103 19545237 10.1042/BA20090085 1:CAS:528:DC%2BD1MXpvF2iu7o%3D
-
(2009)
Biotechnol Appl Biochem
, vol.54
, pp. 93-103
-
-
Jonsson, A.1
Wållberg, H.2
Herne, N.3
Ståhl, S.4
Frejd, F.Y.5
-
3
-
-
70349462873
-
Engineered cystine knot peptides that bind alphavbeta3, alphavbeta5, and alpha5beta1 integrins with low-nanomolar affinity
-
19452550 10.1002/prot.22441 1:CAS:528:DC%2BD1MXhtV2lt7fO
-
RH Kimura AM Levin FV Cochran JR Cochran 2009 Engineered cystine knot peptides that bind alphavbeta3, alphavbeta5, and alpha5beta1 integrins with low-nanomolar affinity Proteins 77 359 369 19452550 10.1002/prot.22441 1:CAS:528:DC%2BD1MXhtV2lt7fO
-
(2009)
Proteins
, vol.77
, pp. 359-369
-
-
Kimura, R.H.1
Levin, A.M.2
Cochran, F.V.3
Cochran, J.R.4
-
4
-
-
33646261864
-
Tumor imaging using a picomolar affinity HER2 binding affibody molecule
-
16618759 10.1158/0008-5472.CAN-05-3521 1:CAS:528:DC%2BD28XjsFSltbs%3D
-
A Orlova M Magnusson TL Eriksson M Nilsson B Larsson I Höidén-Guthenberg, et al. 2006 Tumor imaging using a picomolar affinity HER2 binding affibody molecule Cancer Res 66 4339 4348 16618759 10.1158/0008-5472.CAN-05-3521 1:CAS:528:DC%2BD28XjsFSltbs%3D
-
(2006)
Cancer Res
, vol.66
, pp. 4339-4348
-
-
Orlova, A.1
Magnusson, M.2
Eriksson, T.L.3
Nilsson, M.4
Larsson, B.5
Höidén-Guthenberg, I.6
-
5
-
-
58149336794
-
Engineered cystine-knot peptides that bind alpha(v)beta(3) integrin with antibody-like affinities
-
19038268 10.1016/j.jmb.2008.11.004 1:CAS:528:DC%2BD1MXntFegug%3D%3D
-
AP Silverman AM Levin JL Lahti JR Cochran 2009 Engineered cystine-knot peptides that bind alpha(v)beta(3) integrin with antibody-like affinities J Mol Biol 385 1064 1075 19038268 10.1016/j.jmb.2008.11.004 1:CAS:528: DC%2BD1MXntFegug%3D%3D
-
(2009)
J Mol Biol
, vol.385
, pp. 1064-1075
-
-
Silverman, A.P.1
Levin, A.M.2
Lahti, J.L.3
Cochran, J.R.4
-
6
-
-
33751347582
-
Biopharmaceutical drug discovery using novel protein scaffolds
-
DOI 10.1016/j.copbio.2006.10.003, PII S0958166906001479
-
DS Gill NK Damle 2006 Biopharmaceutical drug discovery using novel protein scaffolds Curr Opin Biotechnol 17 653 658 17055245 10.1016/j.copbio. 2006.10.003 1:CAS:528:DC%2BD28Xht1eqs73N (Pubitemid 44802987)
-
(2006)
Current Opinion in Biotechnology
, vol.17
, Issue.6
, pp. 653-658
-
-
Gill, D.S.1
Damle, N.K.2
-
7
-
-
33947193534
-
Synthetic affibody molecules: A novel class of affinity ligands for molecular imaging of HER2-expressing malignant tumors
-
DOI 10.1158/0008-5472.CAN-06-2887
-
A Orlova V Tolmachev R Pehrson M Lindborg T Tran M Sandström, et al. 2007 Synthetic affibody molecules: a novel class of affinity ligands for molecular imaging of HER2-expressing malignant tumors Cancer Res 67 2178 2186 17332348 10.1158/0008-5472.CAN-06-2887 1:CAS:528:DC%2BD2sXitlSjs78%3D (Pubitemid 46424237)
-
(2007)
Cancer Research
, vol.67
, Issue.5
, pp. 2178-2186
-
-
Orlova, A.1
Tolmachev, V.2
Pehrson, R.3
Lindborg, M.4
Tran, T.5
Sandstrom, M.6
Nilsson, F.Y.7
Wennborg, A.8
Abrahmsen, L.9
Feldwisch, J.10
-
8
-
-
33751295869
-
Advances in targeting human epidermal growth factor receptor-2 signaling for cancer therapy
-
DOI 10.1158/1078-0432.CCR-06-1732
-
F Meric-Bernstam MC Hung 2006 Advances in targeting human epidermal growth factor receptor-2 signaling for cancer therapy Clin Cancer Res 12 6326 6330 17085641 10.1158/1078-0432.CCR-06-1732 1:CAS:528:DC%2BD28XhtFKitLbE (Pubitemid 44799700)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.21
, pp. 6326-6330
-
-
Meric-Bernstam, F.1
Hung, M.-C.2
-
9
-
-
37749004225
-
Protein therapeutics: A summary and pharmacological classification
-
18097458 10.1038/nrd2399 1:CAS:528:DC%2BD1cXht1ygtQ%3D%3D
-
B Leader QJ Baca DE Golan 2008 Protein therapeutics: a summary and pharmacological classification Nat Rev Drug Discov 7 21 39 18097458 10.1038/nrd2399 1:CAS:528:DC%2BD1cXht1ygtQ%3D%3D
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 21-39
-
-
Leader, B.1
Baca, Q.J.2
Golan, D.E.3
-
10
-
-
0038277090
-
Magnetic resonance molecular imaging of the HER-2/neu receptor
-
D Artemov N Mori R Ravi ZM Bhujwalla 2003 Magnetic resonance molecular imaging of the HER-2/neu receptor Cancer Res 63 2723 2727 12782573 1:CAS:528:DC%2BD3sXkt1ajur8%3D (Pubitemid 36667139)
-
(2003)
Cancer Research
, vol.63
, Issue.11
, pp. 2723-2727
-
-
Artemov, D.1
Mori, N.2
Ravi, R.3
Bhujwalla, Z.M.4
-
11
-
-
2942720684
-
Near-infrared fluorescence imaging of HER-2 protein over-expression in tumour cells
-
DOI 10.1007/s00330-004-2257-9
-
I Hilger Y Leistner A Berndt C Fritsche KM Haas H Kosmehl, et al. 2004 Near-infrared fluorescence imaging of HER-2 protein over-expression in tumour cells Eur Radiol 14 1124 1129 15118831 10.1007/s00330-004-2257-9 (Pubitemid 38787258)
-
(2004)
European Radiology
, vol.14
, Issue.6
, pp. 1124-1129
-
-
Hilger, I.1
Leistner, Y.2
Berndt, A.3
Fritsche, C.4
Haas, K.M.5
Kosmehl, H.6
Kaiser, W.A.7
-
12
-
-
34047191078
-
99mTc-chelating mercaptoacetyl-glycyl-glycyl-glycyl (MAG3) sequence
-
DOI 10.1007/s00259-006-0266-4
-
T Engfeldt A Orlova T Tran A Bruskin C Widström AE Karlström, et al. 2007 Imaging of HER2-expressing tumours using a synthetic Affibody molecule containing the 99mTc-chelating mercaptoacetyl-glycyl-glycyl-glycyl (MAG3) sequence Eur J Nucl Med Mol Imaging 34 722 733 17146656 10.1007/s00259-006-0266-4 1:CAS:528:DC%2BD2sXks1agsLY%3D (Pubitemid 46669355)
-
(2007)
European Journal of Nuclear Medicine and Molecular Imaging
, vol.34
, Issue.5
, pp. 722-733
-
-
Engfeldt, T.1
Orlova, A.2
Tran, T.3
Bruskin, A.4
Widstrom, C.5
Karlstrom, A.E.6
Tolmachev, V.7
-
13
-
-
33947318463
-
Affibody® molecules: New protein domains for molecular imaging and targeted tumor therapy
-
FY Nilsson V Tolmachev 2007 Affibody molecules: new protein domains for molecular imaging and targeted tumor therapy Curr Opin Drug Discov Devel 10 167 175 17436552 1:CAS:528:DC%2BD2sXktVOntrw%3D (Pubitemid 46438646)
-
(2007)
Current Opinion in Drug Discovery and Development
, vol.10
, Issue.2
, pp. 167-175
-
-
Nilsson, F.Y.1
Tolmachev, V.2
-
14
-
-
33646259546
-
Affibody-mediated tumour targeting of HER-2 expressing xenografts in mice
-
DOI 10.1007/s00259-005-0012-3
-
AC Steffen A Orlova M Wikman FY Nilsson S Ståhl GP Adams, et al. 2006 Affibody-mediated tumour targeting of HER-2 expressing xenografts in mice Eur J Nucl Med Mol Imaging 33 631 638 16538504 10.1007/s00259-005-0012-3 1:CAS:528:DC%2BD28Xlt1KqsLc%3D (Pubitemid 43846754)
-
(2006)
European Journal of Nuclear Medicine and Molecular Imaging
, vol.33
, Issue.6
, pp. 631-638
-
-
Steffen, A.-C.1
Orlova, A.2
Wikman, M.3
Nilsson, F.Y.4
Stahl, S.5
Adams, G.P.6
Tolmachev, V.7
Carlsson, J.8
-
15
-
-
77956685968
-
64Cu-labeled affibody molecules for imaging of HER2 expressing tumors
-
19779897 10.1007/s11307-009-0256-6
-
Z Cheng OP De Jesus DJ Kramer A De JM Webster O Gheysens, et al. 2009 64Cu-labeled affibody molecules for imaging of HER2 expressing tumors Mol Imaging Biol 12 316 324 19779897 10.1007/s11307-009-0256-6
-
(2009)
Mol Imaging Biol
, vol.12
, pp. 316-324
-
-
Cheng, Z.1
De Jesus, O.P.2
Kramer, D.J.3
De, A.4
Webster, J.M.5
Gheysens, O.6
-
16
-
-
77956176686
-
Structural basis for high-affinity HER2 receptor binding by an engineered protein
-
20696930 10.1073/pnas.1005025107 1:CAS:528:DC%2BC3cXhtFSmt7vK
-
C Eigenbrot M Ultsch A Dubnovitsky L Abrahmsén T Härd 2010 Structural basis for high-affinity HER2 receptor binding by an engineered protein Proc Natl Acad Sci USA 107 15039 15044 20696930 10.1073/pnas.1005025107 1:CAS:528:DC%2BC3cXhtFSmt7vK
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 15039-15044
-
-
Eigenbrot, C.1
Ultsch, M.2
Dubnovitsky, A.3
Abrahmsén, L.4
Härd, T.5
-
17
-
-
67651148169
-
Engineered two-helix small proteins for molecular recognition
-
19422008 10.1002/cbic.200900062 1:CAS:528:DC%2BD1MXmtlOlsr0%3D
-
JM Webster R Zhang SS Gambhir Z Cheng FA Syud 2009 Engineered two-helix small proteins for molecular recognition Chembiochem 10 1293 1296 19422008 10.1002/cbic.200900062 1:CAS:528:DC%2BD1MXmtlOlsr0%3D
-
(2009)
Chembiochem
, vol.10
, pp. 1293-1296
-
-
Webster, J.M.1
Zhang, R.2
Gambhir, S.S.3
Cheng, Z.4
Syud, F.A.5
-
18
-
-
69449083591
-
A 2-helix small protein labeled with 68Ga for PET imaging of HER2 expression
-
19690041 10.2967/jnumed.109.064287 1:CAS:528:DC%2BD1MXhtFOrtbvJ
-
G Ren R Zhang Z Liu JM Webster Z Miao SS Gambhir, et al. 2009 A 2-helix small protein labeled with 68Ga for PET imaging of HER2 expression J Nucl Med 50 1492 1499 19690041 10.2967/jnumed.109.064287 1:CAS:528:DC%2BD1MXhtFOrtbvJ
-
(2009)
J Nucl Med
, vol.50
, pp. 1492-1499
-
-
Ren, G.1
Zhang, R.2
Liu, Z.3
Webster, J.M.4
Miao, Z.5
Gambhir, S.S.6
-
19
-
-
44149108464
-
18F-labeled protein scaffold molecules
-
DOI 10.2967/jnumed.107.047381
-
Z Cheng OP De Jesus M Namavari A De J Levi JM Webster, et al. 2008 Small-animal PET imaging of human epidermal growth factor receptor type 2 expression with site-specific 18F-labeled protein scaffold molecules J Nucl Med 49 804 813 18413392 10.2967/jnumed.107.047381 1:CAS:528:DC%2BD1cXmvVSju7o%3D (Pubitemid 351717547)
-
(2008)
Journal of Nuclear Medicine
, vol.49
, Issue.5
, pp. 804-813
-
-
Cheng, Z.1
De Jesus, O.P.2
Namavari, M.3
De, A.4
Levi, J.5
Webster, J.M.6
Zhang, R.7
Lee, B.8
Syud, F.A.9
Gambhir, S.S.10
-
20
-
-
46049107697
-
Direct site-specific radiolabeling of an Affibody protein with 4-[18F]fluorobenzaldehyde via oxime chemistry
-
18481153 10.1007/s11307-008-0142-7
-
M Namavari O Padilla De Jesus Z Cheng A De E Kovacs J Levi, et al. 2008 Direct site-specific radiolabeling of an Affibody protein with 4-[18F]fluorobenzaldehyde via oxime chemistry Mol Imaging Biol 10 177 181 18481153 10.1007/s11307-008-0142-7
-
(2008)
Mol Imaging Biol
, vol.10
, pp. 177-181
-
-
Namavari, M.1
Padilla De Jesus, O.2
Cheng, Z.3
De, A.4
Kovacs, E.5
Levi, J.6
-
21
-
-
77952565937
-
Small-animal PET imaging of human epidermal growth factor receptor positive tumor with a 64Cu labeled affibody protein
-
20402512 10.1021/bc900515p 1:CAS:528:DC%2BC3cXkvVKrtb8%3D
-
Z Miao G Ren H Liu L Jiang Z Cheng 2010 Small-animal PET imaging of human epidermal growth factor receptor positive tumor with a 64Cu labeled affibody protein Bioconjug Chem 21 947 954 20402512 10.1021/bc900515p 1:CAS:528:DC%2BC3cXkvVKrtb8%3D
-
(2010)
Bioconjug Chem
, vol.21
, pp. 947-954
-
-
Miao, Z.1
Ren, G.2
Liu, H.3
Jiang, L.4
Cheng, Z.5
-
22
-
-
75749091879
-
Evaluation of a (64)Cu-labeled cystine-knot peptide based on agouti-related protein for PET of tumors expressing alphavbeta3 integrin
-
20124048 10.2967/jnumed.109.069831
-
L Jiang RH Kimura Z Miao AP Silverman G Ren H Liu, et al. 2010 Evaluation of a (64)Cu-labeled cystine-knot peptide based on agouti-related protein for PET of tumors expressing alphavbeta3 integrin J Nucl Med 51 251 258 20124048 10.2967/jnumed.109.069831
-
(2010)
J Nucl Med
, vol.51
, pp. 251-258
-
-
Jiang, L.1
Kimura, R.H.2
Miao, Z.3
Silverman, A.P.4
Ren, G.5
Liu, H.6
-
23
-
-
33744831505
-
Indium-111-labeled trastuzumab scintigraphy in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer
-
DOI 10.1200/JCO.2005.03.8448
-
PJ Perik MN Lub-De Hooge JA Gietema WT van der Graaf MA de Korte S Jonkman, et al. 2006 Indium-111-labeled trastuzumab scintigraphy in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer J Clin Oncol 24 2276 2282 16710024 10.1200/JCO.2005.03.8448 1:CAS:528: DC%2BD28XlvV2ksLc%3D (Pubitemid 46630657)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.15
, pp. 2276-2282
-
-
Perik, P.J.1
Lub-De Hooge, M.N.2
Gietema, J.A.3
Van Der Graaf, W.T.A.4
De Korte, M.A.5
Jonkman, S.6
Kosterink, J.G.W.7
Van Veldhuisen, D.J.8
Sleijfer, D.T.9
Jager, P.L.10
De Vries, E.G.E.11
-
24
-
-
77956292811
-
The role of HER2 in cancer therapy and targeted drug delivery
-
20385184 10.1016/j.jconrel.2010.04.009 1:CAS:528:DC%2BC3cXhtFWgt7zL
-
W Tai R Mahato K Cheng 2010 The role of HER2 in cancer therapy and targeted drug delivery J Control Release 146 264 275 20385184 10.1016/j.jconrel.2010.04.009 1:CAS:528:DC%2BC3cXhtFWgt7zL
-
(2010)
J Control Release
, vol.146
, pp. 264-275
-
-
Tai, W.1
Mahato, R.2
Cheng, K.3
-
25
-
-
70349649221
-
A modular platform for the rapid site-specific radiolabeling of proteins with 18F exemplified by quantitative positron emission tomography of human epidermal growth factor receptor 2
-
19736996 10.1021/jm900420c 1:CAS:528:DC%2BD1MXhtFajsr%2FO
-
HS Gill JN Tinianow A Ogasawara JE Flores AN Vanderbilt H Raab, et al. 2009 A modular platform for the rapid site-specific radiolabeling of proteins with 18F exemplified by quantitative positron emission tomography of human epidermal growth factor receptor 2 J Med Chem 52 5816 5825 19736996 10.1021/jm900420c 1:CAS:528:DC%2BD1MXhtFajsr%2FO
-
(2009)
J Med Chem
, vol.52
, pp. 5816-5825
-
-
Gill, H.S.1
Tinianow, J.N.2
Ogasawara, A.3
Flores, J.E.4
Vanderbilt, A.N.5
Raab, H.6
-
26
-
-
42149121917
-
[18F]FBEM-Z(HER2:342)-Affibody molecule-a new molecular tracer for in vivo monitoring of HER2 expression by positron emission tomography
-
18157531 10.1007/s00259-007-0658-0 1:CAS:528:DC%2BD1cXkvVyjuro%3D
-
G Kramer-Marek DO Kiesewetter L Martiniova E Jagoda SB Lee J Capala 2008 [18F]FBEM-Z(HER2:342)-Affibody molecule-a new molecular tracer for in vivo monitoring of HER2 expression by positron emission tomography Eur J Nucl Med Mol Imaging 35 1008 1018 18157531 10.1007/s00259-007-0658-0 1:CAS:528: DC%2BD1cXkvVyjuro%3D
-
(2008)
Eur J Nucl Med Mol Imaging
, vol.35
, pp. 1008-1018
-
-
Kramer-Marek, G.1
Kiesewetter, D.O.2
Martiniova, L.3
Jagoda, E.4
Lee, S.B.5
Capala, J.6
-
27
-
-
77953927395
-
Molecular imaging of HER2-expressing malignant tumors in breast cancer patients using synthetic 111In- or 68Ga-labeled affibody molecules
-
20484419 10.2967/jnumed.109.073239
-
RP Baum V Prasad D Müller C Schuchardt A Orlova A Wennborg, et al. 2010 Molecular imaging of HER2-expressing malignant tumors in breast cancer patients using synthetic 111In- or 68Ga-labeled affibody molecules J Nucl Med 51 892 897 20484419 10.2967/jnumed.109.073239
-
(2010)
J Nucl Med
, vol.51
, pp. 892-897
-
-
Baum, R.P.1
Prasad, V.2
Müller, D.3
Schuchardt, C.4
Orlova, A.5
Wennborg, A.6
|