Dose-response of berberine on hepatic cytochromes P450 mRNA expression and activities in mice

Journal of Ethnopharmacology

Volumn 138, Issue 1, 2011, Pages 111-118

  Guo, Ying ^a,b   Pope, Chad ^c   Cheng, Xingguo ^b   Zhou, Honghao ^a   Klaassen, Curtis D ^b  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^c XenoTech LLC   (United States)

Author keywords

Berberine; Drug drug interactions; Liver

Indexed keywords

BERBERINE; CELL NUCLEUS RECEPTOR; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 1B1; CYTOCHROME P450 2A; CYTOCHROME P450 2B; CYTOCHROME P450 2B9; CYTOCHROME P450 2C; CYTOCHROME P450 2D; CYTOCHROME P450 2E1; CYTOCHROME P450 3A11; HEPATOCYTE NUCLEAR FACTOR 1; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA;

ANIMAL EXPERIMENT; ARTICLE; DOSE RESPONSE; ENZYME ACTIVITY; GENE EXPRESSION; HISTOPATHOLOGY; LIVER FUNCTION; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION;

ADMINISTRATION, ORAL; ANIMALS; ANTICHOLESTEREMIC AGENTS; ANTIHYPERTENSIVE AGENTS; BERBERINE; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION; HERB-DRUG INTERACTIONS; HYPOGLYCEMIC AGENTS; LIVER; MALE; MICE; MICE, INBRED C57BL; PLANT EXTRACTS; PLANTS, MEDICINAL; RNA, MESSENGER;

BERBERIS; COPTIS; HYDRASTIS CANADENSIS; MUS;

EID: 80255123371     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.08.058     Document Type: Article

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