Characterization of C- and N-terminal domains of Aquifex aeolicus MutL endonuclease: N-terminal domain stimulates the endonuclease activity of C-terminal domain in a zinc-dependent manner

Bioscience Reports

Volumn 31, Issue 5, 2011, Pages 309-322

  Iino, Hitoshi ^a,b   Kim, Kwang ^b   Shimada, Atsuhiro ^b   Masui, Ryoji ^a   Kuramitsu, Seiki ^a,b   Fukui, Kenji ^a  

^a Harima Institute ^*  (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

Aquifex aeolicus; DNA repair; Endonuclease; Mismatch repair; MutL; Thermostability

Indexed keywords

MAGNESIUM ION; MONOMER; PROTEIN MUTL; ZINC ION;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; AQUIFEX AEOLICUS; ARTICLE; BACTERIUM EXAMINATION; BIOCHEMISTRY; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME REGULATION; MISMATCH REPAIR; NONHUMAN; NUCLEOTIDE SEQUENCE; PREDICTION; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN QUATERNARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; REACTION ANALYSIS; SEQUENCE ANALYSIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; THERMOSTABILITY;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; DNA MISMATCH REPAIR; DNA REPAIR; DNA-BINDING PROTEINS; ENDONUCLEASES; ENZYME ACTIVATION; HUMANS; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; ZINC;

AQUIFEX AEOLICUS;

EID: 80155139783     PISSN: 01448463     EISSN: None     Source Type: Journal    
DOI: 10.1042/BSR20100116     Document Type: Article

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