메뉴 건너뛰기




Volumn 301, Issue 5, 2011, Pages

Prostaglandin E2 protects murine lungs from bleomycin-induced pulmonary fibrosis and lung dysfunction

Author keywords

Cyclooxygenase; FlexiVent; Mouse

Indexed keywords

BLEOMYCIN; COLLAGEN; ILOPROST; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE;

EID: 80055116289     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00176.2011     Document Type: Article
Times cited : (71)

References (61)
  • 1
    • 0034133548 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: Diagnosis and treatment International consensus statement American Thoracic Society (ATS), and the European Respiratory Society (ERS)
    • American Thoracic Society
    • American Thoracic Society. Idiopathic pulmonary fibrosis: diagnosis and treatment International consensus statement American Thoracic Society (ATS), and the European Respiratory Society (ERS). Am J Respir Crit Care Med 161: 646-664, 2000.
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 646-664
  • 2
    • 0037080547 scopus 로고    scopus 로고
    • American Thoracic Society/European Respiratory Society International Multidisciplinary Consensus Classification of the Idiopathic Interstitial Pneumonias
    • American Thoracic Society/European Respiratory Society, This joint statement of the American Thoracic Society (ATS), and the European Respiratory Society (ERS) was adopted by the ATS board of directors, June 2001 and by the ERS Executive Committee, June 2001
    • American Thoracic Society/European Respiratory Society. American Thoracic Society/European Respiratory Society International Multidisciplinary Consensus Classification of the Idiopathic Interstitial Pneumonias. This joint statement of the American Thoracic Society (ATS), and the European Respiratory Society (ERS) was adopted by the ATS board of directors, June 2001 and by the ERS Executive Committee, June 2001. Am J Respir Crit Care Med 165: 277-304, 2002.
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 277-304
  • 3
    • 0023914820 scopus 로고
    • Simple method of estimating severity of pulmonary fibrosis on a numerical scale
    • Ashcroft T, Simpson JM, Timbrell V. Simple method of estimating severity of pulmonary fibrosis on a numerical scale. J Clin Pathol 41: 467-470, 1988.
    • (1988) J Clin Pathol , vol.41 , pp. 467-470
    • Ashcroft, T.1    Simpson, J.M.2    Timbrell, V.3
  • 4
    • 0018832895 scopus 로고
    • Effect of cyclic AMP on the intracellular degradation of newly synthesized collagen
    • Baum BJ, Moss J, Breul SD, Berg RA, Crystal RG. Effect of cyclic AMP on the intracellular degradation of newly synthesized collagen. J Biol Chem 255: 2843-2847, 1980.
    • (1980) J Biol Chem , vol.255 , pp. 2843-2847
    • Baum, B.J.1    Moss, J.2    Breul, S.D.3    Berg, R.A.4    Crystal, R.G.5
  • 5
    • 0022548668 scopus 로고
    • Modulation of alveolar macrophage-driven fibroblast proliferation by alternative macrophage mediators
    • Bitterman PB, Wewers MD, Rennard SI, Adelberg S, Crystal RG. Modulation of alveolar macrophage-driven fibroblast proliferation by alternative macrophage mediators. J Clin Invest 77: 700-708, 1986.
    • (1986) J Clin Invest , vol.77 , pp. 700-708
    • Bitterman, P.B.1    Wewers, M.D.2    Rennard, S.I.3    Adelberg, S.4    Crystal, R.G.5
  • 7
    • 80052518623 scopus 로고    scopus 로고
    • Prostaglandin E2 and the pathogenesis of pulmonary fibrosis
    • Bozyk PD, Moore BB. Prostaglandin E2 and the pathogenesis of pulmonary fibrosis. Am J Respir Cell Mol Biol 45: 445-452, 2011.
    • (2011) Am J Respir Cell Mol Biol , vol.45 , pp. 445-452
    • Bozyk, P.D.1    Moore, B.B.2
  • 11
    • 0030614799 scopus 로고    scopus 로고
    • Nuclear factor-kappaB activation in human monocytes stimulated with lipopolysaccharide is inhibited by fibroblast conditioned medium and exogenous PGE2
    • Conte E, Bonaiuto C, Nesci C, Crimi N, Vancheri C, Messina A. Nuclear factor-kappaB activation in human monocytes stimulated with lipopolysaccharide is inhibited by fibroblast conditioned medium and exogenous PGE2. FEBS Lett 400: 315-318, 1997.
    • (1997) FEBS Lett , vol.400 , pp. 315-318
    • Conte, E.1    Bonaiuto, C.2    Nesci, C.3    Crimi, N.4    Vancheri, C.5    Messina, A.6
  • 12
    • 75949130829 scopus 로고    scopus 로고
    • Strategies for treating idiopathic pulmonary fibrosis
    • du Bois RM. Strategies for treating idiopathic pulmonary fibrosis. Nat Rev Drug Discov 9: 129-140, 2010.
    • (2010) Nat Rev Drug Discov , vol.9 , pp. 129-140
    • du Bois, R.M.1
  • 13
    • 0023690417 scopus 로고
    • Tumor necrosis factor interacts with interleukin-1 and interferons to inhibit fibroblast proliferation via fibroblast prostaglandin-dependent and -independent mechanisms
    • Elias JA. Tumor necrosis factor interacts with interleukin-1 and interferons to inhibit fibroblast proliferation via fibroblast prostaglandin-dependent and -independent mechanisms. Am Rev Respir Dis 138: 652-658, 1988.
    • (1988) Am Rev Respir Dis , vol.138 , pp. 652-658
    • Elias, J.A.1
  • 14
    • 0025093211 scopus 로고
    • In vitro production of B cell growth factor and B cell differentiation factor by peripheral blood mononuclear cells and bronchoalveolar lavage T lymphocytes from patients with idiopathic pulmonary fibrosis
    • Emura M, Nagai S, Takeuchi M, Kitaichi M, Izumi T. In vitro production of B cell growth factor and B cell differentiation factor by peripheral blood mononuclear cells and bronchoalveolar lavage T lymphocytes from patients with idiopathic pulmonary fibrosis. Clin Exp Immunol 82: 133-139, 1990.
    • (1990) Clin Exp Immunol , vol.82 , pp. 133-139
    • Emura, M.1    Nagai, S.2    Takeuchi, M.3    Kitaichi, M.4    Izumi, T.5
  • 15
    • 0037652234 scopus 로고    scopus 로고
    • Immunohistochemical expression of cyclooxygenase isoenzymes and downstream enzymes in human lung tumors
    • Ermert L, Dierkes C, Ermert M. Immunohistochemical expression of cyclooxygenase isoenzymes and downstream enzymes in human lung tumors. Clin Cancer Res 9: 1604-1610, 2003.
    • (2003) Clin Cancer Res , vol.9 , pp. 1604-1610
    • Ermert, L.1    Dierkes, C.2    Ermert, M.3
  • 16
    • 0037364184 scopus 로고    scopus 로고
    • Cyclooxygenase-2-dependent and thromboxane-dependent vascular and bronchial responses are regulated via p38 mitogen-activated protein kinase in control and endotoxin-primed rat lungs
    • Ermert M, Kuttner D, Eisenhardt N, Dierkes C, Seeger W, Ermert L. Cyclooxygenase-2-dependent and thromboxane-dependent vascular and bronchial responses are regulated via p38 mitogen-activated protein kinase in control and endotoxin-primed rat lungs. Lab Invest 83: 333-347, 2003.
    • (2003) Lab Invest , vol.83 , pp. 333-347
    • Ermert, M.1    Kuttner, D.2    Eisenhardt, N.3    Dierkes, C.4    Seeger, W.5    Ermert, L.6
  • 18
    • 0026341797 scopus 로고
    • Interleukin-4 stimulates collagen synthesis by normal and scleroderma fibroblasts in dermal equivalents
    • Fertin C, Nicolas JF, Gillery P, Kalis B, Banchereau J, Maquart FX. Interleukin-4 stimulates collagen synthesis by normal and scleroderma fibroblasts in dermal equivalents. Cell Mol Biol 37: 823-829, 1991.
    • (1991) Cell Mol Biol , vol.37 , pp. 823-829
    • Fertin, C.1    Nicolas, J.F.2    Gillery, P.3    Kalis, B.4    Banchereau, J.5    Maquart, F.X.6
  • 19
    • 0025005862 scopus 로고
    • The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes
    • Fu JY, Masferrer JL, Seibert K, Raz A, Needleman P. The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes. J Biol Chem 265: 16737-16740, 1990.
    • (1990) J Biol Chem , vol.265 , pp. 16737-16740
    • Fu, J.Y.1    Masferrer, J.L.2    Seibert, K.3    Raz, A.4    Needleman, P.5
  • 20
    • 0019913443 scopus 로고
    • The effect and interaction of bradykinin and prostaglandins on protein and collagen production by lung fibroblasts
    • Goldstein RH, Polgar P. The effect and interaction of bradykinin and prostaglandins on protein and collagen production by lung fibroblasts. J Biol Chem 257: 8630-8633, 1982.
    • (1982) J Biol Chem , vol.257 , pp. 8630-8633
    • Goldstein, R.H.1    Polgar, P.2
  • 21
  • 22
    • 0017094438 scopus 로고
    • Purification of the cyclooxygenase that forms prostaglandins. Demonstration of two forms of iron in the holoenzyme
    • Hemler M, Lands WE. Purification of the cyclooxygenase that forms prostaglandins. Demonstration of two forms of iron in the holoenzyme. J Biol Chem 251: 5575-5579, 1976.
    • (1976) J Biol Chem , vol.251 , pp. 5575-5579
    • Hemler, M.1    Lands, W.E.2
  • 23
  • 25
    • 33847037980 scopus 로고    scopus 로고
    • 2 inhibits collagen expression and proliferation in patient-derived normal lung fibroblasts via E prostanoid 2 receptor and cAMP signaling
    • Huang S, Wettlaufer SH, Hogaboam C, Aronoff DM, Peters-Golden M. Prostaglandin E2 inhibits collagen expression and proliferation in patient-derived normal lung fibroblasts via E prostanoid 2 receptor and cAMP signaling. Am J Physiol Lung Cell Mol Physiol 292: L405-L413, 2007.
    • (2007) Am J Physiol Lung Cell Mol Physiol , vol.292
    • Huang, S.1    Wettlaufer, S.H.2    Hogaboam, C.3    Aronoff, D.M.4    Peters-Golden, M.5
  • 26
    • 53449089229 scopus 로고    scopus 로고
    • Prostaglandin E2 inhibits specific lung fibroblast functions via selective actions of PKA and Epac-1
    • Huang SK, Wettlaufer SH, Chung J, Peters-Golden M. Prostaglandin E2 inhibits specific lung fibroblast functions via selective actions of PKA and Epac-1. Am J Respir Cell Mol Biol 39: 482-489, 2008.
    • (2008) Am J Respir Cell Mol Biol , vol.39 , pp. 482-489
    • Huang, S.K.1    Wettlaufer, S.H.2    Chung, J.3    Peters-Golden, M.4
  • 28
    • 0027468941 scopus 로고
    • Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines
    • Jones DA, Carlton DP, McIntyre TM, Zimmerman GA, Prescott SM. Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines. J Biol Chem 268: 9049-9054, 1993.
    • (1993) J Biol Chem , vol.268 , pp. 9049-9054
    • Jones, D.A.1    Carlton, D.P.2    McIntyre, T.M.3    Zimmerman, G.A.4    Prescott, S.M.5
  • 30
    • 0035070056 scopus 로고    scopus 로고
    • Cyclooxygenase-2 deficiency results in a loss of the anti-proliferative response to transforming growth factor-beta in human fibrotic lung fibroblasts and promotes bleomycin-induced pulmonary fibrosis in mice
    • Keerthisingam CB, Jenkins RG, Harrison NK, Hernandez-Rodriguez NA, Booth H, Laurent GJ, Hart SL, Foster ML, McAnulty RJ. Cyclooxygenase-2 deficiency results in a loss of the anti-proliferative response to transforming growth factor-beta in human fibrotic lung fibroblasts and promotes bleomycin-induced pulmonary fibrosis in mice. Am J Pathol 158: 1411-1422, 2001.
    • (2001) Am J Pathol , vol.158 , pp. 1411-1422
    • Keerthisingam, C.B.1    Jenkins, R.G.2    Harrison, N.K.3    Hernandez-Rodriguez, N.A.4    Booth, H.5    Laurent, G.J.6    Hart, S.L.7    Foster, M.L.8    McAnulty, R.J.9
  • 35
    • 0242319836 scopus 로고    scopus 로고
    • Prostaglandin E2 inhibits fibroblast to myofibroblast transition via E. prostanoid receptor 2 signaling and cyclic adenosine monophosphate elevation
    • Kolodsick JE, Peters-Golden M, Larios J, Toews GB, Thannickal VJ, Moore BB. Prostaglandin E2 inhibits fibroblast to myofibroblast transition via E. prostanoid receptor 2 signaling and cyclic adenosine monophosphate elevation. Am J Respir Cell Mol Biol 29: 537-544, 2003.
    • (2003) Am J Respir Cell Mol Biol , vol.29 , pp. 537-544
    • Kolodsick, J.E.1    Peters-Golden, M.2    Larios, J.3    Toews, G.B.4    Thannickal, V.J.5    Moore, B.B.6
  • 36
    • 0018835906 scopus 로고
    • Mononuclear cell modulation of connective tissue function: Suppression of fibroblast growth by stimulation of endogenous prostaglandin production
    • Korn JH, Halushka PV, LeRoy EC. Mononuclear cell modulation of connective tissue function: suppression of fibroblast growth by stimulation of endogenous prostaglandin production. J Clin Invest 65: 543-554, 1980.
    • (1980) J Clin Invest , vol.65 , pp. 543-554
    • Korn, J.H.1    Halushka, P.V.2    Leroy, E.C.3
  • 37
    • 0027469850 scopus 로고
    • Expression of the protein product of the prostaglandin synthase-2/TIS10 gene in mitogenstimulated Swiss 3T3 cells
    • Kujubu DA, Reddy ST, Fletcher BS, Herschman HR. Expression of the protein product of the prostaglandin synthase-2/TIS10 gene in mitogenstimulated Swiss 3T3 cells. J Biol Chem 268: 5425-5430, 1993.
    • (1993) J Biol Chem , vol.268 , pp. 5425-5430
    • Kujubu, D.A.1    Reddy, S.T.2    Fletcher, B.S.3    Herschman, H.R.4
  • 38
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25: 402-408, 2001.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 41
    • 0027293391 scopus 로고
    • Expression of mRNA for cyclooxygenase- 1 and cyclooxygenase-2 in human tissues
    • O'Neill GP, Ford-Hutchinson AW. Expression of mRNA for cyclooxygenase- 1 and cyclooxygenase-2 in human tissues. FEBS Lett 330: 156-160, 1993.
    • (1993) FEBS Lett , vol.330 , pp. 156-160
    • O'Neill, G.P.1    Ford-Hutchinson, A.W.2
  • 43
    • 0034292842 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-1 and -2 mRNA in rat tissues: Tissue-specific difference in the expression of the basal level of mRNA
    • Okamoto T, Hino O. Expression of cyclooxygenase-1 and -2 mRNA in rat tissues: tissue-specific difference in the expression of the basal level of mRNA. Int J Mol Med 6: 455-457, 2000.
    • (2000) Int J Mol Med , vol.6 , pp. 455-457
    • Okamoto, T.1    Hino, O.2
  • 44
    • 0028302812 scopus 로고
    • Inhibition of the transendothelial migration of human T lymphocytes by prostaglandin E2
    • Oppenheimer-Marks N, Kavanaugh AF, Lipsky PE. Inhibition of the transendothelial migration of human T lymphocytes by prostaglandin E2. J Immunol 152: 5703-5713, 1994.
    • (1994) J Immunol , vol.152 , pp. 5703-5713
    • Oppenheimer-Marks, N.1    Kavanaugh, A.F.2    Lipsky, P.E.3
  • 45
    • 33847411035 scopus 로고    scopus 로고
    • Inflammatory cell phenotyping of the pulmonary interstitium in idiopathic interstitial pneumonia
    • Parra ER, Kairalla RA, Ribeiro de Carvalho CR, Eher E, Capelozzi VL. Inflammatory cell phenotyping of the pulmonary interstitium in idiopathic interstitial pneumonia. Respiration 74: 159-169, 2007.
    • (2007) Respiration , vol.74 , pp. 159-169
    • Parra, E.R.1    Kairalla, R.A.2    de Carvalho, R.C.R.3    Eher, E.4    Capelozzi, V.L.5
  • 46
    • 0003019810 scopus 로고
    • An analysis of pressure-volume characteristics of the lungs
    • Salazar E, Knowles JH. An analysis of pressure-volume characteristics of the lungs. J Appl Physiol 19: 97-104, 1964.
    • (1964) J Appl Physiol , vol.19 , pp. 97-104
    • Salazar, E.1    Knowles, J.H.2
  • 47
    • 0020320880 scopus 로고
    • Modulation of collagen production by fibroblasts. Effects of chronic exposure to agonists that increase intracellular cyclic AMP
    • Saltzman LE, Moss J, Berg RA, Hom B, Crystal RG. Modulation of collagen production by fibroblasts. Effects of chronic exposure to agonists that increase intracellular cyclic AMP. Biochem J 204: 25-30, 1982.
    • (1982) Biochem J , vol.204 , pp. 25-30
    • Saltzman, L.E.1    Moss, J.2    Berg, R.A.3    Hom, B.4    Crystal, R.G.5
  • 49
    • 0028224194 scopus 로고
    • Subsets of murine lung fibroblasts express membrane-bound and soluble IL-4 receptors. Role of IL-4 in enhancing fibroblast proliferation and collagen synthesis
    • Sempowski GD, Beckmann MP, Derdak S, Phipps RP. Subsets of murine lung fibroblasts express membrane-bound and soluble IL-4 receptors. Role of IL-4 in enhancing fibroblast proliferation and collagen synthesis. J Immunol 152: 3606-3614, 1994.
    • (1994) J Immunol , vol.152 , pp. 3606-3614
    • Sempowski, G.D.1    Beckmann, M.P.2    Derdak, S.3    Phipps, R.P.4
  • 50
    • 0029975669 scopus 로고    scopus 로고
    • Prostaglandin endoperoxide H synthases-1 and -2
    • Smith WL, Dewitt DL. Prostaglandin endoperoxide H synthases-1 and -2. Adv Immunol 62: 167-215, 1996.
    • (1996) Adv Immunol , vol.62 , pp. 167-215
    • Smith, W.L.1    Dewitt, D.L.2
  • 52
    • 13844318314 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: Challenges and opportunities for the clinician and investigator
    • Swigris JJ, Kuschner WG, Kelsey JL, Gould MK. Idiopathic pulmonary fibrosis: challenges and opportunities for the clinician and investigator. Chest 127: 275-283, 2005.
    • (2005) Chest , vol.127 , pp. 275-283
    • Swigris, J.J.1    Kuschner, W.G.2    Kelsey, J.L.3    Gould, M.K.4
  • 53
    • 70350457951 scopus 로고    scopus 로고
    • Prostaglandin E2 inhibits advanced glycation end productinduced adhesion molecule expression, cytokine production, and lymphocyte proliferation in human peripheral blood mononuclear cells
    • Takahashi HK, Liu K, Wake H, Mori S, Zhang J, Liu R, Yoshino T, Nishibori M. Prostaglandin E2 inhibits advanced glycation end productinduced adhesion molecule expression, cytokine production, and lymphocyte proliferation in human peripheral blood mononuclear cells. J Pharmacol Exp Ther 331: 656-670, 2009.
    • (2009) J Pharmacol Exp Ther , vol.331 , pp. 656-670
    • Takahashi, H.K.1    Liu, K.2    Wake, H.3    Mori, S.4    Zhang, J.5    Liu, R.6    Yoshino, T.7    Nishibori, M.8
  • 54
    • 0346961783 scopus 로고    scopus 로고
    • The lung as a privileged site for the beneficial actions of PGE2
    • Vancheri C, Mastruzzo C, Sortino MA, Crimi N. The lung as a privileged site for the beneficial actions of PGE2. Trends Immunol 25: 40-46, 2004.
    • (2004) Trends Immunol , vol.25 , pp. 40-46
    • Vancheri, C.1    Mastruzzo, C.2    Sortino, M.A.3    Crimi, N.4
  • 56
    • 0034038206 scopus 로고    scopus 로고
    • Different expression of TNF-alpha receptors and prostaglandin E(2)Production in normal and fibrotic lung fibroblasts: Potential implications for the evolution of the inflammatory process
    • Vancheri C, Sortino MA, Tomaselli V, Mastruzzo C, Condorelli F, Bellistri G, Pistorio MP, Canonico PL, Crimi N. Different expression of TNF-alpha receptors and prostaglandin E(2)Production in normal and fibrotic lung fibroblasts: potential implications for the evolution of the inflammatory process. Am J Respir Cell Mol Biol 22: 628-634, 2000.
    • (2000) Am J Respir Cell Mol Biol , vol.22 , pp. 628-634
    • Vancheri, C.1    Sortino, M.A.2    Tomaselli, V.3    Mastruzzo, C.4    Condorelli, F.5    Bellistri, G.6    Pistorio, M.P.7    Canonico, P.L.8    Crimi, N.9
  • 58
    • 0028924146 scopus 로고
    • Cultured lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis have a diminished capacity to synthesize prostaglandin E2 and to express cyclooxygenase-2
    • Wilborn J, Crofford LJ, Burdick MD, Kunkel SL, Strieter RM, Peters-Golden M. Cultured lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis have a diminished capacity to synthesize prostaglandin E2 and to express cyclooxygenase-2. J Clin Invest 95: 1861-1868, 1995.
    • (1995) J Clin Invest , vol.95 , pp. 1861-1868
    • Wilborn, J.1    Crofford, L.J.2    Burdick, M.D.3    Kunkel, S.L.4    Strieter, R.M.5    Peters-Golden, M.6
  • 59
    • 60649102339 scopus 로고    scopus 로고
    • Pulmonary fibrosis: Pathogenesis, etiology and regulation
    • Wilson MS, Wynn TA. Pulmonary fibrosis: pathogenesis, etiology and regulation. Mucosal Immunol 2: 103-121, 2009.
    • (2009) Mucosal Immunol , vol.2 , pp. 103-121
    • Wilson, M.S.1    Wynn, T.A.2
  • 60
    • 0037775352 scopus 로고    scopus 로고
    • IL13 effector functions
    • Wynn TA. IL13 effector functions. Annu Rev Immunol 21: 425-456, 2003.
    • (2003) Annu Rev Immunol , vol.21 , pp. 425-456
    • Wynn, T.A.1
  • 61
    • 77954573839 scopus 로고    scopus 로고
    • A prostacyclin analogue, iloprost, protects from bleomycininduced pulmonary fibrosis in mice (Abstract)
    • Zhu Y, Liu Y, Zhou W, Xiang R, Jiang L, Huang K, Xiao Y, Guo Z, Gao J. A prostacyclin analogue, iloprost, protects from bleomycininduced pulmonary fibrosis in mice (Abstract). Respir Res 11: 34, 2010.
    • (2010) Respir Res , vol.11 , pp. 34
    • Zhu, Y.1    Liu, Y.2    Zhou, W.3    Xiang, R.4    Jiang, L.5    Huang, K.6    Xiao, Y.7    Guo, Z.8    Gao, J.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.