Molecular mechanisms of antibacterial and antitumor actions of designed surfactant-like peptides

Biomaterials

Volumn 33, Issue 2, 2012, Pages 592-603

  Chen, Cuixia ^a   Hu, Jing ^a   Zhang, Shengzhong ^a   Zhou, Peng ^a   Zhao, Xichen ^b   Xu, Hai ^a   Zhao, Xiubo ^c   Yaseen, Mohammed ^c   Lu, Jian R ^c  

^a CHINA UNIVERSITY OF PETROLEUM   (China)

^b Qingdao Economic and Technological Development Area First People's Hospital   (China)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Antimicrobial peptides; Cell selectivity; Membrane permeability; Peptide self assembly; Surfactant like peptides

Indexed keywords

AMPHIPHILICITY; ANTI-TUMORS; ANTIBACTERIAL TREATMENT; ANTIMICROBIAL PEPTIDE; BACILLUS SUBTILIS; BACTERICIDAL EFFECTS; BIOMIMETIC PEPTIDES; BIOMIMICRY; CANCEROUS CELLS; CATIONIC PEPTIDES; CELL SELECTIVITY; COMBINED EFFECT; CONCENTRATION RANGES; EXPERIMENTAL CONDITIONS; FLUORESCENCE ASSAY; HELA CELL; HUMAN RED BLOOD CELL; INNATE IMMUNE SYSTEMS; MAMMALIAN CELLS; MEMBRANE PERMEABILITY; MICELLAR CONCENTRATION; MOLECULAR MECHANISM; STRUCTURAL SIMILARITY; SURFACTANT-LIKE PEPTIDES;

BACTERIA; BACTERICIDES; BACTERIOLOGY; BIOCOMPATIBILITY; BIOMIMETICS; BLOOD; CELL MEMBRANES; CYTOLOGY; ESCHERICHIA COLI; MAMMALS; SELF ASSEMBLY; SURFACE ACTIVE AGENTS;

PEPTIDES;

ANTINEOPLASTIC ANTIBIOTIC; CYTOKINE; POLYPEPTIDE ANTIBIOTIC AGENT;

ANTIBACTERIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BACILLUS SUBTILIS; BACTERIAL MEMBRANE; BACTERICIDAL ACTIVITY; BIOCOMPATIBILITY; CELL MEMBRANE; CELL STRAIN 3T3; CYTOTOXICITY; DRUG MECHANISM; DRUG STRUCTURE; ERYTHROCYTE; ESCHERICHIA COLI; GENETIC TRANSCRIPTION; HELA CELL; HEMOLYSIS; HUMAN; HUMAN CELL; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; STATIC ELECTRICITY;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTICARCINOGENIC AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; BACILLUS SUBTILIS; CELL MEMBRANE; CELL PROLIFERATION; ERYTHROCYTES; ESCHERICHIA COLI; HELA CELLS; HEMOLYSIS; HUMANS; MICE; MICELLES; NIH 3T3 CELLS; STRUCTURE-ACTIVITY RELATIONSHIP; SURFACE-ACTIVE AGENTS;

BACILLUS SUBTILIS; ESCHERICHIA COLI; MAMMALIA;

EID: 80055106640     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.09.059     Document Type: Article

References (45)

1. Boman H.G. Peptide antibiotics and their role in innate immunity. Annu Rev Immunol 1995, 13:61-92.
2. Oren Z., Shai Y. Mode of action of linear amphipathic alpha-helical antimicrobial peptides. Biopolymers 1998, 47:451-463.
3. Zasloff M. Antimicrobial peptides of multicellular organisms. Nature 2002, 415:389-395.
4. Shai Y. Mode of action of membrane active antimicrobial peptides. Biopolymers 2002, 66:236-248.
5. Yeaman M.R., Yount N.Y. Mechanisms of antimicrobial peptide action and resistance. Pharmacol Rev 2003, 55:27-55.
6. Hancock R.E.W., Sahl H.G. Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies. Nat Biotechnol 2006, 24:1551-1557.
7. Hancock R.E.W. Cationic peptides: effectors in innate immunity and novel antimicrobials. Lancet Infect Dis 2001, 1:156-164.
8. Sitaram N., Nagaraj R. Interaction of antimicrobial peptides with biological and model membranes: structural and charge requirements for activity. Biochim Biophys Acta 1999, 1462:29-54.
9. Matsuzaki K. Control of cell selectivity of antimicrobial peptides. Biochim Biophys Acta 2009, 1788:1687-1692.
10. Bell G., Gouyon P.H. Arming the enemy: the evolution of resistance to self-proteins. Microbiology 2003, 149:1367-1375.
11. Jenssen H., Hamill P., Hancock R.E.W. Peptide antimicrobial agents. Clin Microbiol Rev 2006, 19:491-511.
12. Wang H., Xu K., Liu L., Tan J.P.K., Chen Y., Li Y., et al. The efficacy of self-assembled cationic antimicrobial peptide nanoparticles against cryptococcus neoformans for the treatment of meningitis. Biomaterials 2010, 31:2874-2881.
13. Chen C., Pan F., Zhang S., Hu J., Cao M., Wang J., et al. Antibacterial activities of short designer peptides: a link between propensity for nanostructuring and capacity for membrane destabilization. Biomacromolecules 2010, 11:402-411.
14. Liu L., Xu K., Wang H., Tan P.K.J., Fan W., Venkatraman S.S., et al. Self-assembled cationic peptide nanoparticles as an efficient antimicrobial agent. Nat Nanotechnol 2009, 4:457-463.
15. Makovitzki A., Baram Y., Shai Y. Palmitoyl di- and tri-cationic antimicrobial lipopeptides: in vitro and in vivo activities, self-assembly to nano structures and a plausible mode of action. Biochemistry 2008, 47:10630-10636.
16. Makovitzki A., Avrahami D., Shai Y. Ultrashort antibacterial and antifungal lipopeptides. Proc Natl Acad Sci USA 2006, 103:15997-16002.
17. Laverty G., McLaughlin M., Shaw C., Gorman S.P., Gilmore B.F. Antimicrobial activity of short, synthetic cationic lipopeptides. Chem Biol Drug Des 2010, 75:563-569.
18. Wiradharma N., Khoe U., Hauser C.A., Seow S.V., Zhang S., Yang Y.Y. Synthetic cationic amphiphilic α-helical peptides as antimicrobial agents. Biomaterials 2011, 32:2204-2212.
19. Mader J.S., Hoskin D.W. Cationic antimicrobial peptides as novel cytotoxic agents for cancer treatment. Exp Opin Investig Drugs 2006, 15:933-946.
20. Hoskin D.W., Ramamoorthy A. Studies on anticancer activities of antimicrobial peptides. Biochim Biophys Acta 2008, 1778:357-375.
21. Papo N., Shai Y. Host defense peptides as new weapons in cancer treatment. Cell Mol Life Sci 2005, 62:784-790.
22. Xu H., Wang J., Han S., Wang J., Yu D., Zhang H., et al. Hydrophobic region induced transitions in self-assembled peptide nanostrucutres. Langmuir 2009, 25:4115-4123.
23. Wang J., Han S., Meng G., Xu H., Xia D., Zhao X., et al. Dynamic self-assembly of surfactant-like peptides A6K and A9K. Soft Matter 2009, 5:3870-3878.
24. Burdick M.D., Harris A., Reid C.J., Iwamura T., Hollingsworth M.A. Oligosaccharides expressed on MUC1 produced by pancreatic and colon tumor cell lines. J Biol Chem 1997, 272:24198-24202.
25. Izabela D., Barbara S.P., Stanislaw S., Zbigniew F. Changes in electric charge and phospholipids composition in human colorectal cancer cells. Mol Cell Biochem 2005, 276:113-119.
26. Lee H.S., Park C.B., Kim J.M., Jang S.A., Park I.Y., Kim M.S., et al. Mechanism of anticancer activity of buforin IIb, a histone H2A-derived peptide. Cancer Lett 2008, 271:47-55.
27. Kleeff J., Ishiwata T., Kumbasar A., Friess H., Büchler M.W., Lander A.D., et al. The cell-surface heparan sulfate proteoglycan glypican-1 regulates growth factor action in pancreatic carcinoma cells and is overexpressed in human pancreatic cancer. J Clin Invest 1998, 102:1662-1673.
28. Aarskog N.K., Vedeler C.A. Real-time quantitative polymerase chain reaction-A new method that detects both the peripheral myelin protein 22 duplication in Charcot-Marie-Tooth type 1A disease and the peripheral myelin protein 22 deletion in hereditary europathy with liability to pressure palsies. Hum Genet 2000, 107:494-498.
29. Haney E.F., Vogel H.J. NMR of antimicrobial peptides. Annu Rep NMR Spectrosc 2009, 69:1-51.
30. Zhao X., Pan F., Perumal S., Xu H., Lu J.R., Webster J.R.P. Interfacial assembly of cationic peptide surfactants. Soft Matter 2009, 5:1630-1638.
31. Vauthey S., Santoso S., Gong H., Watson N., Zhang S. Molecular self-assembly of surfactant-like peptides to form nanotubes and nanovesicles. Proc Natl Acad Sci USA 2002, 99:5355-5360.
32. von Maltzahn G., Vauthey S., Santoso S., Zhang S. Positively charged surfactant-like peptides self-assemble into nanostructures. Langmuir 2003, 19:4332-4337.
33. Aguiar J., Carpena P., Molina-Bolívar J.A., Ruiz C.C. On the determination of the critical micelle concentration by the pyrene 1:3 ratio method. J Colloid Interface Sci 2003, 258:116-122.
34. Rochet J.C., Lansbury P.T. Amyloid fibrillogenesis: themes and variations. Curr Opin Struc Biol 2000, 10:60-68.
35. Tosteson M.T., Holmes S.J., Razin M., Tosteson D.C. Melittin lysis of red cells. J Membr Biol 1985, 87:35-44.
36. De G.D., Zangerle P.F., Gevaert Y., Fassotte M.F., Beguin Y., Noizat-Pirenne F., et al. Direct stimulation of cytokines (IL-1 beta, TNF-alpha, IL-6, IL-2, IFN-gamma and GM-CSF) in whole blood. I. Comparison with isolated PBMC stimulation. Cytokine 1992, 4:239-248.
37. Hancock R.E.W., Lehrer R.I. Cationic peptides: a new source of antibiotics. Trends Biotechnol 1998, 16:82-88.
38. Sarig H., Rotem S., Ziserman L., Danino D., Mor A. Impact of self-assembly properties on antibacterial activity of short acyl-lysine oligomers. Antimicrob Agents Chemother 2008, 52:4308-4314.
39. Chen Y., Guarnieri M., Vasil A., Vasil M., Mant C., Hodges R. Role of peptide hydrophobicity in the mechanism of action of alpha-helical antimicrobial peptides. Antimicrob Agents Chemother 2007, 51:1398-1406.
40. Rotem S., Mor A. Antimicrobial peptide mimics for improved therapeutic properties. Biochim Biophys Acta 2009, 1788:1582-1592.
41. Dathe M., Wieprecht T. Structural features of helical antimicrobial peptides: their potential to modulate activity on model membranes and biological cells. Biochim Biophys Acta 1999, 1462:71-87.
42. Zasloff M., Martint B., Chen H.C. Antimicrobial activity of synthetic magainin peptides and several analogues. Proc Nail Acad Sci USA 1988, 85:910-913.
43. Cruciani R.A., Barker J.L., Zasloff M., Chen H.C., Colamonici O. Antibiotic magainins exert cytolytic activity against transformed cell lines through channel formation. Proc Nati Acad Sci USA 1991, 88:3792-3796.
44. Dathe M., Nikolenko H., Meyer J., Beyermann M., Bienert M. Optimization of the antimicrobial activity of magainin peptides by modification of charge. FEBS Lett 2001, 501:146-150.
45. Hristova K., Dempsey C.E., White S.H. Structure, location, and lipid perturbations of melittin at the membrane interface. Biophys J 2001, 80:801-811.