A peptide of sparc interferes with the interaction between Caspase8 and Bcl2 to resensitize Chemoresistant tumors and enhance their regression in vivo

PLoS ONE

Volumn 6, Issue 11, 2011, Pages

  Rahman, Mahbuba ^a,b   Chan, Annie P K ^a,b   Tai, Isabella T ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b BRITISH COLUMBIA CANCER AGENCY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 8; FLUOROURACIL; OSTEONECTIN; PROTEIN BCL 2; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER CELL; CANCER REGRESSION; CELL PROLIFERATION; CELL VIABILITY; CHEMOSENSITIVITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VIVO STUDY; MOUSE; MUTATION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; BREAST NEOPLASMS; CASPASE 8; CASPASE INHIBITORS; COLORECTAL NEOPLASMS; DRUG RESISTANCE, NEOPLASM; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; FLUOROURACIL; HUMANS; IMMUNOENZYME TECHNIQUES; IMMUNOPRECIPITATION; MICE; MICE, NUDE; MUTAGENESIS, SITE-DIRECTED; OSTEONECTIN; PANCREATIC NEOPLASMS; PEPTIDE FRAGMENTS; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA, SMALL INTERFERING; TUMOR CELLS, CULTURED;

EID: 80055106355     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0026390     Document Type: Article

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