Increased fibrovascular invasion of subcutaneous polyvinyl alcohol sponges in SPARC-null mice

Wound Repair and Regeneration

Volumn 9, Issue 6, 2001, Pages 522-530

  Bradshaw, Amy D ^a   Reed, May J ^b   Carbon, Juliet G ^a   Pinney, Emmett ^c   Brekken, Rolf A ^a   Sage, E Helene ^a  

^a HOPE HEART INSTITUTE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c Advanced Tissue Sciences Liquidating Trust   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OSTEONECTIN; POLYVINYL ALCOHOL SPONGE; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DENSITY; CELL INVASION; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIUM CELL; FIBROBLAST; IMMUNOREACTIVITY; IMPLANTATION; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; VASCULAR ENDOTHELIUM;

ANIMALS; ENDOTHELIAL GROWTH FACTORS; FIBROBLASTS; IMMUNOHISTOCHEMISTRY; LYMPHOKINES; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; NEOVASCULARIZATION, PHYSIOLOGIC; OSTEONECTIN; POLYVINYL ALCOHOL; SKIN; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0035727654     PISSN: 10671927     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1524-475x.2001.00522.x     Document Type: Article

References (35)

1. Diversity of function is inherent in matricellular proteins: An appraisal of thrombospondin 1
2. SPARC a matricellular protein: At the crossroads of cell-matrix communication
3. SPARC, a secreted protein associated with morphogenesis and tissue remodeling, induces expression of metalloproteinases in fibroblasts through a novel extracellular matrix-dependent pathway
4. Regulation of gene expression by SPARC during angiogenesis in vitro. Changes in fibronectin, thrombospondin-1, and plasminogen activator inhibitor-1
5. Differential expression of SPARC and thrombospondin 1 in wound repair: Immunolocalization and in situ hybridization
6. SPARC deficiency leads to early onset cataractogenesis
7. Mice deficient for the secreted glycoprotein SPARC/osteonectin/BM 40 develop normally but show severe age-onset cataract formation and disruption of the lens
8. Osteopenia and decreased bone formation in osteonectin-deficient mice
9. SPARC-null mice exhibit accelerated cutaneous wound closure in the dermis, and increased cellular invasion in a sponge model of angiogenesis
10. SPARC, a matricellular protein that functions in cellular differentiation and tissue response to injury
11. SPARC is a source of copper-binding peptides that stimulate angiogenesis
12. Expression of SPARC during development of the chicken chorioallantoic membrane: Evidence for regulated proteolysis in vivo
13. Pieces of eight: Bioactive fragments of extracellular proteins as regulators of angiogenesis
14. Between molecules and morphology. Extracellular matrix and the creation of vascular form
15. Molecular angiogenesis
16. Sponge-induced angiogenesis in mice and the pharmacological reactivity of the neovasculature quantitated by a fluorimetric method
17. Effects of platelet activating factor (PAF) and other vascoconstrictors on a model of angiogenesis in the mouse
18. Cyclo-oxygenase enhances basic fibroblast growth factor-induced angiogenesis through induction of vascular endothelial growth factor in rat sponge models
19. Neovascularization in aged mice - Delayed angiogenesis is coincident with decreased levels of transforming growth factor β1 and type I collagen
20. Novel mouse endothelial cell surface marker is suppressed during differentiation of the blood brain barrier
21. Ultrastructural localization of the vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) receptor-2 (flk-1, KDR) in normal mouse kidney and in the hyperpermeable vessels induced by VPF/VEGF-expressing tumors and adenoviral vectors
22. Primary mesenchymal cells isolated from SPARC-null mice exhibit altered morphology and rates of proliferation
23. Monoclonal antibody analysis of the proliferating cell nuclear antigen (PCNA). Structural conservation and the detection of a nucleolar form
24. SPARC (BM40, osteonectin) inhibits the mitogenic effect of vascular endothelial growth factor on microvascular endothelial cells
25. 2+-binding glycoprotein SPARC modulates cell cycle progression in bovine aortic endothelial cells
26. Suppression of SPARC expression by antisense RNA abrogates the tumorgenicity of human melanoma cells
27. SPARC antagonizes the effect of basic fibroblast growth factor on the migration of bovine aortic endothelial cells
28. The extracellular glycoprotein SPARC interacts with platelet-derived growth factor (PDGF) -AB and BB and inhibits the binding of PDGF to its receptors
29. In vivo detection of human vascular endothelial growth factor promoter activity in transgenic mouse skin
30. Hypoxia regulates the expression of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) and its receptors in human skin
31. Vascular endothelial growth factor is induced in response to transforming growth factor-β in fibroblastic and epithelial cells
32. Human three-dimensional fibroblast cultures express angiogenic activity
33. SPARC regulates the expression of collagen type I and transforming growth factor-β1 in mesangial cells
34. Collagen accumulation is decreased in SPARC-null mice with bleomycin-induced pulmonary fibrosis
35. Bleomycin-induced pulmonary injury in mice deficient in SPARC