Expanded CUG repeats dysregulate RNA splicing by altering the stoichiometry of the muscleblind 1 complex

Journal of Biological Chemistry

Volumn 286, Issue 44, 2011, Pages 38427-38438

  Paul, Sharan ^a,e   Dansithong, Warunee ^a   Jog, Sonali P ^a   Holt, Ian ^b,c   Mittal, Saloni ^d   Brook, J David ^d   Morris, Glenn E ^b,c   Comai, Lucio ^a   Reddy, Sita ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b ROBERT JONES AND AGNES HUNT ORTHOPAEDIC HOSPITAL   (United Kingdom)

^c KEELE UNIVERSITY   (United Kingdom)

^d UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^e UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MYOBLASTS; MYOTONIC DYSTROPHY; PROTEIN SYNTHESIS; RIBONUCLEOPROTEIN COMPLEX; RNA PROCESSING; RNA SPLICING; STEADY-STATE LEVEL;

BIOSYNTHESIS; DEFECTS; PROTEINS; STOICHIOMETRY;

RNA;

DDX17 PROTEIN; DHX9 PROTEIN; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A2; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN B1; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN F; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN H; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN H2; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN H3; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN L; MUSCLEBLIND 1 COMPLEX; PROTEIN KINASE C ALPHA; REGULATOR PROTEIN; RETINOIC ACID INDUCIBLE PROTEIN I; RIBONUCLEOPROTEIN; RNA; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN COS7; CONTROLLED STUDY; CUG REPEAT; HUMAN; HUMAN CELL; MYOBLAST; MYOTONIC DYSTROPHY; MYOTONIC DYSTROPHY 1; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PURIFICATION; PROTEIN STABILITY; PROTEIN SYNTHESIS; RNA PROCESSING; RNA SPLICING; STEADY STATE; STOICHIOMETRY; TRINUCLEOTIDE REPEAT;

ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; COS CELLS; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEINS; HUMANS; IMMUNOPRECIPITATION; MASS SPECTROMETRY; MUSCLE, SKELETAL; MYOTONIC DYSTROPHY; PROTEIN INTERACTION MAPPING; RNA SPLICING; RNA, SMALL INTERFERING; RNA-BINDING PROTEINS; SUBCELLULAR FRACTIONS;

EID: 80055097731     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.255224     Document Type: Article

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