Rapid anastomosis of endothelial progenitor cell-derived vessels with host vasculature is promoted by a high density of cotransplanted fibroblasts

Tissue Engineering - Part A

Volumn 16, Issue 2, 2010, Pages 585-594

  Chen, Xiaofang ^a   Aledia, Anna S ^a   Popson, Stephanie A ^b   Him, Linda ^b   Hughes, Christopher C W ^a,b   George, Steven C ^a,b  

^a University of California at Irvine   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD VESSELS; CELL CULTURE; ENDOTHELIAL CELLS; FIBROBLASTS; HISTOLOGY; NUTRIENTS; SELF ASSEMBLY; TISSUE;

COCULTURE; CONVECTIVE TRANSPORT; CORD BLOOD; ENDOTHELIAL PROGENITOR CELLS; ENGINEERED TISSUES; FIBRIN GELS; HIGH DENSITY; HUMAN UMBILICAL VEINS; IN-VITRO; IN-VIVO; LOW DENSITY; TUBULAR NETWORKS; VASCULATURE; WASTE PRODUCTS;

BLOOD VESSEL PROSTHESES;

MUS;

ACTIN;

ANASTOMOSIS; ANGIOGENESIS; ANIMAL; ARTICLE; BLOOD VESSEL; CELL COUNT; CYTOLOGY; ENDOTHELIUM CELL; FIBROBLAST; FLOW CYTOMETRY; HUMAN; IMPLANT; METABOLISM; METHODOLOGY; MOUSE; PHYSIOLOGY; STEM CELL; TISSUE ENGINEERING; TRANSPLANTATION;

ACTINS; ANASTOMOSIS, SURGICAL; ANIMALS; BLOOD VESSELS; CELL COUNT; ENDOTHELIAL CELLS; FIBROBLASTS; FLOW CYTOMETRY; HUMANS; IMPLANTS, EXPERIMENTAL; MICE; NEOVASCULARIZATION, PHYSIOLOGIC; STEM CELLS; TISSUE ENGINEERING;

EID: 77049126246     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2009.0491     Document Type: Conference Paper

References (38)

1. Langer, R., and Vacanti, J.P. Tissue engineering. Science 260, 920, 1993.
2. Vacanti, J.P., and Langer, R. Tissue engineering: the design and fabrication of living replacement devices for surgical reconstruction and transplantation. Lancet 354 Suppl 1, SI32, 1999.
3. Falabella, A.F., Schachner, L.A., Valencia, I.C., and Eaglstein, W.H. The use of tissue-engineered skin (Apligraf) to treat a newborn with epidermolysis bullosa. Arch Dermatol 135, 1219, 1999.
4. Ando, W., Tateishi, K., Hart, D.A., Katakai, D., Tanaka, Y., Nakata, K., Hashimoto, J., Fujie, H., Shino, K., Yoshikawa, H., and Nakamura, N. Cartilage repair using an in vitro generated scaffold-free tissue-engineered construct derived from porcine synovial mesenchymal stem cells. Biomaterials 28, 5462, 2007.
5. Kang, P.M., Haunstetter, A., Aoki, H., Usheva, A., and Izumo, S. Morphological and molecular characterization of adult cardiomyocyte apoptosis during hypoxia and reox-ygenation. Circ Res 87, 118, 2000.
6. Laflamme, M.A., Chen, K.Y., Naumova, A.V., Muskheli, V., Fugate, J.A., Dupras, S.K., Reinecke, H., Xu, C., Hassani-pour, M., Police, S., O'Sullivan, C., Collins, L., Chen, Y., Minami, E., Gill, E.A., Ueno, S., Yuan, C., Gold, J., and Murry, C.E. Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts. Nat Biotechnol 25, 1015, 2007.
7. Tremblay, P.L., Hudon, V., Berthod, F., Germain, L., and Auger, F.A. Inosculation of tissue-engineered capillaries with the host's vasculature in a reconstructed skin transplanted on mice. Am J Transplant 5, 1002, 2005.
8. Levenberg, S., Rouwkema, J., Macdonald, M., Garfein, E.S., Kohane, D.S., Darland, D.C., Marini, R., van Blitterswijk, C.A., Mulligan, R.C., D'Amore, P.A., and Langer, R. Engineering vascularized skeletal muscle tissue. Nat Biotechnol 23, 879, 2005.
9. Caspi, O., Lesman, A., Basevitch, Y., Gepstein, A., Arbel, G., Habib, I.H., Gepstein, L., and Levenberg, S. Tissue engineering of vascularized cardiac muscle from human embryonic stem cells. Circ Res 100, 263, 2007.
10. Jain, R.K., Au, P., Tam, J., Duda, D.G., and Fukumura, D. Engineering vascularized tissue. Nat Biotechnol 23, 821, 2005.
11. Koike, N., Fukumura, D., Gralla, O., Au, P., Schechner, J.S., and Jain, R.K. Tissue engineering: creation of long-lasting blood vessels. Nature 428, 138, 2004.
12. Black, A.F., Berthod, F., L'Heureux, N., Germain, L., and Auger, F.A. In vitro reconstruction of a human capillary-like network in a tissue-engineered skin equivalent. FASEB J 12, 1331, 1998.
13. Nor, J.E., Peters, M.C., Christensen, J.B., Sutorik, M.M., Linn, S., Khan, M.K., Addison, C.L., Mooney, D.J., and Polverini, P.J. Engineering and characterization of functional human microvessels in immunodeficient mice. Lab Invest 81, 453, 2001.
14. Ferreira, L.S., Gerecht, S., Shieh, H.F., Watson, N., Rupnick, M.A., Dallabrida, S.M., Vunjak-Novakovic, G., and Langer, R. Vascular progenitor cells isolated from human embryonic stem cells give rise to endothelial and smooth muscle like cells and form vascular networks in vivo. Circ Res 101, 286, 2007.
15. McCloskey, K.E., Gilroy, M.E., and Nerem, R.M. Use of embryonic stem cell-derived endothelial cells as a cell source to generate vessel structures in vitro. Tissue Eng 11, 497, 2005.
16. Drukker, M., Katchman, H., Katz, G., Even-Tov Friedman, S., Shezen, E., Hornstein, E., Mandelboim, O., Reisner, Y., and Benvenisty, N. Human embryonic stem cells and their differentiated derivatives are less susceptible to immune rejection than adult cells. Stem Cells 24, 221, 2006.
17. Traktuev, D.O., Prater, D.N., Merfeld-Clauss, S., Sanjee-vaiah, A.R., Murphy, M., Johnstone, B.H., Ingram, D.A., and March, K.L. Robust functional vascular network formation in vivo by cooperation of adipose progenitor and endothelial cells. Circ Res 104, 1410, 2009.
18. Melero-Martin, J.M., De Obaldia, M.E., Kang, S.Y., Khan, Z.A., Yuan, L., Oettgen, P., and Bischoff, J. Engineering robust and functional vascular networks in vivo with human adult and cord blood-derived progenitor cells. Circ Res 103, 194, 2008.
19. Au, P., Daheron, L.M., Duda, D.G., Cohen, K.S., Tyrrell, J.A., Lanning, R.M., Fukumura, D., Scadden, D.T., and Jain, R.K. Differential in vivo potential of endothelial progenitor cells from human umbilical cord blood and adult peripheral blood to form functional long-lasting vessels. Blood 111, 1302, 2008.
20. Ingram, D.A., Mead, L.E., Tanaka, H., Meade, V., Fenoglio, A., Mortell, K., Pollok, K., Ferkowicz, M.J., Gilley, D., and Yoder, M.C. Identification of a novel hierarchy of endothe-lial progenitor cells using human peripheral and umbilical cord blood. Blood 104, 2752, 2004.
21. Chade, A.R., Zhu, X., Lavi, R., Krier, J.D., Pislaru, S., Simari, R.D., Napoli, C., Lerman, A., and Lerman, L.O. Endothelial progenitor cells restore renal function in chronic experimental renovascular disease. Circulation 119, 547, 2009.
22. Nagano, M., Yamashita, T., Hamada, H., Ohneda, K., Ki-mura, K., Nakagawa, T., Shibuya, M., Yoshikawa, H., and Ohneda, O. Identification of functional endothelial progenitor cells suitable for the treatment of ischemic tissue using human umbilical cord blood. Blood 110, 151, 2007.
23. Chen, X., Aledia, A.S., Ghajar, C.M., Griffith, C.K., Putnam, A.J., Hughes, C.C., and George, S.C. Prevascularization of a fibrin-based tissue construct accelerates the formation of functional anastomosis with host vasculature. Tissue Eng Part A 15, 1363, 2009.
24. Melero-Martin, J.M., Khan, Z.A., Picard, A., Wu, X., Par-uchuri, S., and Bischoff, J. In vivo vasculogenic potential of human blood-derived endothelial progenitor cells. Blood 109, 4761, 2007.
25. Griffith, C.K., Miller, C., Sainson, R.C., Calvert, J.W., Jeon, N.L., Hughes, C.C., and George, S.C. Diffusion limits of an in vitro thick prevascularized tissue. Tissue Eng 11, 257, 2005.
26. Ghajar, C.M., Chen, X., Harris, J.W., Suresh, V., Hughes, C.C., Jeon, N.L., Putnam, A.J., and George, S.C. The effect of matrix density on the regulation of 3-D capillary morphogenesis. Biophys J 94, 1930, 2008.
27. Nakatsu, M.N., Sainson, R.C., Aoto, J.N., Taylor, K.L., Ait-kenhead, M., Perez-del-Pulgar, S., Carpenter, P.M., and Hughes, C.C. Angiogenic sprouting and capillary lumen formation modeled by human umbilical vein endothelial cells (HUVEC) in fibrin gels: the role of fibroblasts and angiopoietin-1. Microvasc Res 66, 102, 2003.
28. Schechner, J.S., Nath, A.K., Zheng, L., Kluger, M.S., Hughes, C.C., Sierra-Honigmann, M.R., Lorber, M.I., Tellides, G., Kashgarian, M., Bothwell, A.L., and Pober, J.S. In vivo formation of complex microvessels lined by human endothelial cells in an immunodeficient mouse. Proc Natl Acad Sci USA 97, 9191, 2000.
29. Yang, J., Nagavarapu, U., Relloma, K., Sjaastad, M.D., Moss, W.C.,Passaniti,A.,andHerron,G.S.Telomerizedhumanmicro-vasculature is functional in vivo. Nat Biotechnol 19, 219, 2001.
30. Enis, D.R., Shepherd, B.R., Wang, Y., Qasim, A., Shanahan, C.M., Weissberg, P.L., Kashgarian, M., Pober, J.S., and Schechner, J.S. Induction, differentiation, and remodeling of blood vessels after transplantation of Bcl-2-transduced en-dothelial cells. Proc Natl Acad Sci USA 102, 425, 2005.
31. Hristov, M., Erl, W., and Weber, P.C. Endothelial progenitor cells: mobilization, differentiation, and homing. Arterioscler Thromb Vasc Biol 23, 1185, 2003.
32. Asahara, T., Murohara, T., Sullivan, A., Silver, M., van der Zee, R., Li, T., Witzenbichler, B., Schatteman, G., and Isner, J.M. Isolation of putative progenitor endothelial cells for angiogenesis. Science 275, 964, 1997.
33. Quirici, N., Soligo, D., Caneva, L., Servida, F., Bossolasco, P., and Deliliers, G.L. Differentiation and expansion of endo-thelial cells from human bone marrow CD133(\+) cells. Br J Haematol 115, 186, 2001.
34. Zhu, C., Ying, D., Mi, J., Li, L., Zeng, W., Hou, C., Sun, J., Yuan, W., Wen, C., and Zhang, W. Development of anti-atherosclerotic tissue-engineered blood vessel by A20-regulated endothelial progenitor cells seeding decellularized vascular matrix. Biomaterials 29, 2628, 2008.
35. Droetto, S., Viale, A., Primo, L., Jordaney, N., Bruno, S., Pagano, M., Piacibello, W., Bussolino, F., and Aglietta, M. Vasculogenic potential of long term repopulating cord blood progenitors. FASEB J 18, 1273, 2004.
36. Khan, Z.A., Melero-Martin, J.M., Wu, X., Paruchuri, S., Boscolo, E., Mulliken, J.B., and Bischoff, J. Endothelial progenitor cells from infantile hemangioma and umbilical cord blood display unique cellular responses to endostatin. Blood 108, 915, 2006.
37. Ghajar, C.M., Blevins, K.S., Hughes, C.C., George, S.C., and Putnam, A.J. Mesenchymal stem cells enhance angiogenesis in mechanically viable prevascularized tissues via early matrix metalloproteinase upregulation. Tissue Eng 12, 2875, 2006.
38. Ghajar, C.M., George, S.C., and Putnam, A.J. Matrix me-talloproteinase control of capillary morphogenesis. Crit Rev Eukaryot Gene Expr 18, 251, 2008.