Manganese potentiates LPS-induced heme-oxygenase 1 in microglia but not dopaminergic cells: Role in controlling microglial hydrogen peroxide and inflammatory cytokine output

NeuroToxicology

Volumn 32, Issue 6, 2011, Pages 683-692

  Dodd, Celia A ^a   Filipov, Nikolay M ^a  

^a UNIVERSITY OF GEORGIA   (United States)

Author keywords

Cytokines; H 2O 2; Heme oxygenase 1; Manganese; Microglia; N27 cells; Nitric oxide; Nrf2; Small Maf

Indexed keywords

HEME OXYGENASE 1; HYDROGEN PEROXIDE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; MANGANESE; MESSENGER RNA; TRANSCRIPTION FACTOR MAF; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; ENZYME ACTIVITY; ENZYME INDUCTION; GENE EXPRESSION; MICROGLIA; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ANIMALS; CELL LINE; CHLORIDES; CYTOKINES; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEME OXYGENASE (DECYCLIZING); HEME OXYGENASE-1; HYDROGEN PEROXIDE; INFLAMMATION MEDIATORS; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MAF TRANSCRIPTION FACTORS; MANGANESE COMPOUNDS; MEMBRANE PROTEINS; MESENCEPHALON; MICE; MICROGLIA; NEURONS; NF-E2-RELATED FACTOR 2; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; RATS; RNA, MESSENGER; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 80055077873     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2011.09.002     Document Type: Article

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