Evaluation of oxidative stress and antioxidative action of green tea catechins in patients treated with tamoxifen: A randomized open-label, crossover study

Mediterranean Journal of Nutrition and Metabolism

Volumn 4, Issue 2, 2011, Pages 127-132

  Ronzani, G ^a   Giaretta, R ^b   Morello, M ^a  

^a Dietetics and Clinical Nutrition Unit   (Italy)

^b Vicenza League Against Cancer   (Italy)

Author keywords

BAP test; Breast cancer; D Roms test; Green tea catechins; Oxidative stress; Tamoxifen

Indexed keywords

BENZO[A]PYRENE; CATECHIN; EPIGALLOCATECHIN GALLATE; GREEN TEA EXTRACT; REACTIVE OXYGEN METABOLITE; TAMOXIFEN;

ABSENCE OF SIDE EFFECTS; ADULT; AGED; ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD SAMPLING; BREAST CANCER; CLINICAL ARTICLE; CLINICAL EFFECTIVENESS; CLINICAL EVALUATION; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG EFFECT; DRUG EFFICACY; DRUG HALF LIFE; DRUG MECHANISM; DRUG SCREENING; FEMALE; HUMAN; OUTCOME ASSESSMENT; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TREATMENT DURATION;

EID: 80055074103     PISSN: 1973798X     EISSN: 19737998     Source Type: Journal    
DOI: 10.1007/s12349-010-0020-0     Document Type: Article

References (20)

1. (2002) Nolvadex [tamoxifen citrate]. In: Medwatch 2002 Safety Information Summaries. US Food and Drug Administration, Washington. http://www.fda.gov/ medwatch/SAFETY/2002/safety02.htm#nolvad
2. Murata Y, Ogawa Y, Saibara T et al (2003) Tamoxifen-induced non-alcoholic steatohepatitis in patients with breast cancer: determination of a suitable biopsy site for diagnosis. Oncol Rep 10:97-100
3. Ogawa Y, Murata Y, Nishioka A et al (1998) Tamoxifen-induced fatty liver in patients with breast cancer. Lancet 351:725 (Pubitemid 28105346)
4. Oien KA, Moffat D, Curry GW et al (1999) Cirrhosis with ste-atohepatitis after adjuvant tamoxifen. Lancet 353:36-37
5. Toler SM (2004) Oxidative stress plays an important role in the pathogenesis of drug-induced retinopathy. Exp Biol Med (May-wood) 229:607-615 (Pubitemid 38878905)
6. Dragan YP, Fahey S, Nuwaysir E et al (1996) The effect of tamoxifen and two of its non-isomerizable fixed-ring analogs on multistage rat hepatocarcinogenesis. Carcinogenesis 17:585-594 (Pubitemid 26085343)
7. Wiseman H (1995) Tamoxifen as an antioxidant and cardiopro-tectant. Biochem Soc Symp 61:209-219
8. Wiseman H, Paganga G, Rice-Evans C et al (1993) Protective actions of tamoxifen and 4-hydroxytamoxifen against oxidative damage to human low-density lipoproteins: a mechanism accounting for the cardioprotective action of tamoxifen? Bio-chem J 292:365-368
9. Brown NS, Bicknell R (2001) Hypoxia and oxidative stress in breast cancer. Oxidative stress: its effects on the growth, meta-static potential and response to therapy of breast cancer. Breast Cancer Res 3:323-327 (Pubitemid 32851163)
10. Schiff R, Reddy P, Ahotupa M et al (2000) Oxidative stress and AP-1 activity in tamoxifen-resistant breast tumors in vivo. J Natl Cancer Inst 92:1926-1934 (Pubitemid 32036923)
11. Parvez S, Tabassum H, Rehman H et al (2006) Catechin prevents tamoxifen-induced oxidative stress and biochemical perturbations in mice. Toxicology 225:109-118 (Pubitemid 44108371)
12. Anjaneyulu M, Tirkey N, Chopra K (2003) Attenuation of cyclosporine-induced renal dysfunction by catechin: possible antioxidant mechanism. Ren Fail 25:691-707 (Pubitemid 37187664)
13. Singh D, Chander V, Chopra K (2005) Protective effect of cat-echin on ischemia-reperfusion-induced renal injury in rats. Pharmacol Rep 57:70-76 (Pubitemid 40601543)
14. Alberti A, Bolognini L, Macciantelli D et al (2000) The radical cation of N, N-diethyl-para-phenylendiamine: a possible indicator of oxidative stress in biological samples. Res Chem Intermed 26:253-267
15. Benzie IF, Strain JJ (1996) The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": the FRAP assay. Anal Biochem 15(239):70-76
16. Tabassum H, Parvez S, Rehman H et al (2007) Catechin as an antioxidant in liver mitochondrial toxicity: inhibition of tamoxi-fen-induced protein oxidation and lipid peroxidation. J Biochem Mol Toxicol 21:110-117 (Pubitemid 47080837)
17. Ferlini C, Scambia G, Marone M et al (1999) Tamoxifen induces oxidative stress and apoptosis in oestrogen receptor-negative human cancer cell lines. Br J Cancer 79:257-263 (Pubitemid 29002294)
18. Seely D, Mills EJ, Wu P et al (2005) The effects of green tea consumption on incidence of breast cancer and recurrence of breast cancer: a systematic review and meta-analysis. Integr Cancer Ther 4:144-155 (Pubitemid 40726879)
19. Sartippour MR, Shao ZM, Heber D et al (2002) Green tea inhibits vascular endothelial growth factor (VEGF) induction in human breast cancer cells. J Nutr 132:2307-2311 (Pubitemid 34851667)
20. Cornelli U, Terranova R, Luca S et al (2001) Bioavailability and antioxidant activity of some food supplements in men and women using the D-Roms test as a marker of oxidative stress. J Nutr 31:3208-3211 (Pubitemid 33136136)