Anti-UVC irradiation and metal chelation properties of 6-benzoyl-5,7-dihydroxy-4-phenyl-chromen-2-one: An implications for anti-cataract agent

International Journal of Molecular Sciences

Volumn 12, Issue 10, 2011, Pages 7059-7076

  Liao, Jiahn Haur ^a   Wu, Tzu Hua ^b   Hsu, Feng Lin ^b   Huang, Yi Shiang ^a   Chiang, Po Hung ^b   Huang, Zih You ^c   Huang, Chi Hsien ^b   Wu, Shih Hsiung ^a   Lin, Mei Hsiang ^b  

^a INSTITUTE OF BIOLOGICAL CHEMISTRY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

crystallin; Anti cataract; Coumarin; Iron chelation; Irradiation

Indexed keywords

5,6 DIHYDROXY 6 (4 HYDROXYBENZOYL) 4 PHENYL 2H CHROMEN 2 ONE; 6 BENZOYL 5,7 DIHYDROXY 4 PHENYL CHROMEN 2 ONE; COUMARIN DERIVATIVE; GAMMA CRYSTALLIN; UNCLASSIFIED DRUG; CHELATING AGENT; COUMARIN; DNA; HYDROXYL RADICAL; METAL; PROTECTIVE AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CATARACT; CHELATION THERAPY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFICACY; DRUG POTENCY; DRUG SAFETY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXIDATION; PHOTODEGRADATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTON NUCLEAR MAGNETIC RESONANCE; TURBIDITY; ULTRAVIOLET C RADIATION; ANIMAL; CHEMISTRY; DRUG EFFECTS; LENS; METABOLISM; OXIDATIVE STRESS; PHOTOLYSIS; PHOTOMETRY; PLASMID; RADIATION RESPONSE; SWINE; TOXICITY; ULTRAVIOLET RADIATION;

SUS;

ANIMALS; CATARACT; CHELATING AGENTS; COUMARINS; DNA; HYDROXYL RADICAL; LENS, CRYSTALLINE; METALS; NEPHELOMETRY AND TURBIDIMETRY; OXIDATIVE STRESS; PHOTOLYSIS; PLASMIDS; PROTECTIVE AGENTS; SWINE; ULTRAVIOLET RAYS;

EID: 80055049909     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms12107059     Document Type: Article

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