-
1
-
-
23944467250
-
Adaptive immune responses in acute and chronic hepatitis C virus infection
-
Bowen DG, Walker CM. Adaptive immune responses in acute and chronic hepatitis C virus infection. Nature 2005; 436: 946-952.
-
(2005)
Nature
, vol.436
, pp. 946-952
-
-
Bowen, D.G.1
Walker, C.M.2
-
2
-
-
22344448015
-
Mutational escape from CD8+ T cell immunity: HCV evolution, from chimpanzees to man
-
Bowen DG, Walker CM. Mutational escape from CD8+ T cell immunity: HCV evolution, from chimpanzees to man. J Exp Med 2005; 201: 1709-1714.
-
(2005)
J Exp Med
, vol.201
, pp. 1709-1714
-
-
Bowen, D.G.1
Walker, C.M.2
-
3
-
-
77954674575
-
Coexpression of PD-1, 2B4, CD160 and KLRG1 on exhausted HCV-specific CD8+ T cells is linked to antigen recognition and T cell differentiation
-
Bengsch B, Seigel B, Ruhl M, Timm J, Kuntz M, Blum HE, et al. Coexpression of PD-1, 2B4, CD160 and KLRG1 on exhausted HCV-specific CD8+ T cells is linked to antigen recognition and T cell differentiation. PLoS Pathog 2010; 6: e1000947.
-
(2010)
PLoS Pathog
, vol.6
-
-
Bengsch, B.1
Seigel, B.2
Ruhl, M.3
Timm, J.4
Kuntz, M.5
Blum, H.E.6
-
4
-
-
2442684151
-
Memory CD8 T-cell differentiation during viral infection
-
Wherry EJ, Ahmed R. Memory CD8 T-cell differentiation during viral infection. J Virol 2004; 78: 5535-5545.
-
(2004)
J Virol
, vol.78
, pp. 5535-5545
-
-
Wherry, E.J.1
Ahmed, R.2
-
5
-
-
0037105567
-
Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection
-
Wedemeyer H, He XS, Nascimbeni M, Davis AR, Greenberg HB, Hoofnagle JH, et al. Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection. J Immunol 2002; 169: 3447-3458.
-
(2002)
J Immunol
, vol.169
, pp. 3447-3458
-
-
Wedemeyer, H.1
He, X.S.2
Nascimbeni, M.3
Davis, A.R.4
Greenberg, H.B.5
Hoofnagle, J.H.6
-
6
-
-
32544459770
-
Restoring function in exhausted CD8 T cells during chronic viral infection
-
Barber DL, Wherry EJ, Masopust D, Zhu B, Allison JP, Sharpe AH, et al. Restoring function in exhausted CD8 T cells during chronic viral infection. Nature 2006; 439: 682-687.
-
(2006)
Nature
, vol.439
, pp. 682-687
-
-
Barber, D.L.1
Wherry, E.J.2
Masopust, D.3
Zhu, B.4
Allison, J.P.5
Sharpe, A.H.6
-
7
-
-
33749009709
-
Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction
-
Trautmann L, Janbazian L, Chomont N, Said EA, Gimmig S, Bessette B, et al. Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction. Nat Med 2006; 12: 1198-1202.
-
(2006)
Nat Med
, vol.12
, pp. 1198-1202
-
-
Trautmann, L.1
Janbazian, L.2
Chomont, N.3
Said, E.A.4
Gimmig, S.5
Bessette, B.6
-
8
-
-
33750691709
-
PD-1 expression in acute hepatitis C virus (HCV) infection is associated with HCV-specific CD8 exhaustion
-
Urbani S, Amadei B, Tola D, Massari M, Schivazappa S, Missale G, et al. PD-1 expression in acute hepatitis C virus (HCV) infection is associated with HCV-specific CD8 exhaustion. J Virol 2006; 80: 11398-11403.
-
(2006)
J Virol
, vol.80
, pp. 11398-11403
-
-
Urbani, S.1
Amadei, B.2
Tola, D.3
Massari, M.4
Schivazappa, S.5
Missale, G.6
-
9
-
-
33947407689
-
Liver-infiltrating lymphocytes in chronic human hepatitis C virus infection display an exhausted phenotype with high levels of PD-1 and low levels of CD127 expression
-
Radziewicz H, Ibegbu CC, Fernandez ML, Workowski KA, Obideen K, Wehbi M, et al. Liver-infiltrating lymphocytes in chronic human hepatitis C virus infection display an exhausted phenotype with high levels of PD-1 and low levels of CD127 expression. J Virol 2007; 81: 2545-2553.
-
(2007)
J Virol
, vol.81
, pp. 2545-2553
-
-
Radziewicz, H.1
Ibegbu, C.C.2
Fernandez, M.L.3
Workowski, K.A.4
Obideen, K.5
Wehbi, M.6
-
10
-
-
62249172189
-
Enhancing SIV-specific immunity in vivo by PD-1 blockade
-
Velu V, Titanji K, Zhu B, Husain S, Pladevega A, Lai L, et al. Enhancing SIV-specific immunity in vivo by PD-1 blockade. Nature 2009; 458: 206-210.
-
(2009)
Nature
, vol.458
, pp. 206-210
-
-
Velu, V.1
Titanji, K.2
Zhu, B.3
Husain, S.4
Pladevega, A.5
Lai, L.6
-
11
-
-
44649188658
-
Functional restoration of HCV-specific CD8 T cells by PD-1 blockade is defined by PD-1 expression and compartmentalization
-
Nakamoto N, Kaplan DE, Coleclough J, Li Y, Valiga ME, Kaminski M, et al. Functional restoration of HCV-specific CD8 T cells by PD-1 blockade is defined by PD-1 expression and compartmentalization. Gastroenterology 2008; 134: 1927-1937.
-
(2008)
Gastroenterology
, vol.134
, pp. 1927-1937
-
-
Nakamoto, N.1
Kaplan, D.E.2
Coleclough, J.3
Li, Y.4
Valiga, M.E.5
Kaminski, M.6
-
12
-
-
39549087674
-
CD161 expression on hepatitis C virus-specific CD8+ T cells suggests a distinct pathway of T cell differentiation
-
Northfield JW, Kasprowicz V, Lucas M, Kersting N, Bengsch B, Kim A, et al. CD161 expression on hepatitis C virus-specific CD8+ T cells suggests a distinct pathway of T cell differentiation. HEPATOLOGY 2008; 47: 396-406.
-
(2008)
HEPATOLOGY
, vol.47
, pp. 396-406
-
-
Northfield, J.W.1
Kasprowicz, V.2
Lucas, M.3
Kersting, N.4
Bengsch, B.5
Kim, A.6
-
13
-
-
34548680261
-
Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction
-
Kaufmann DE, Kavanagh DG, Pereyra F, Zaunders JJ, Mackey EW, Miura T, et al. Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction. Nat Immunol 2007; 8: 1246-1254.
-
(2007)
Nat Immunol
, vol.8
, pp. 1246-1254
-
-
Kaufmann, D.E.1
Kavanagh, D.G.2
Pereyra, F.3
Zaunders, J.J.4
Mackey, E.W.5
Miura, T.6
-
14
-
-
61449181280
-
Synergistic reversal of intrahepatic HCV-specific CD8 T cell exhaustion by combined PD-1/CTLA-4 blockade
-
Nakamoto N, Cho H, Shaked A, Olthoff K, Valiga ME, Kaminski M, et al. Synergistic reversal of intrahepatic HCV-specific CD8 T cell exhaustion by combined PD-1/CTLA-4 blockade. PLoS Pathog 2009; 5: e1000313.
-
(2009)
PLoS Pathog
, vol.5
-
-
Nakamoto, N.1
Cho, H.2
Shaked, A.3
Olthoff, K.4
Valiga, M.E.5
Kaminski, M.6
-
15
-
-
69449091993
-
Negative immune regulator Tim-3 is overexpressed on T cells in hepatitis C virus infection and its blockade rescues dysfunctional CD4+ and CD8+ T cells
-
Golden-Mason L, Palmer BE, Kassam N, Townshend-Bulson L, Livingston S, McMahon BJ, et al. Negative immune regulator Tim-3 is overexpressed on T cells in hepatitis C virus infection and its blockade rescues dysfunctional CD4+ and CD8+ T cells. J Virol 2009; 83: 9122-9130.
-
(2009)
J Virol
, vol.83
, pp. 9122-9130
-
-
Golden-Mason, L.1
Palmer, B.E.2
Kassam, N.3
Townshend-Bulson, L.4
Livingston, S.5
McMahon, B.J.6
-
16
-
-
77949793555
-
A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection
-
Mengshol JA, Golden-Mason L, Arikawa T, Smith M, Niki T, McWilliams R, et al. A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection. PLoS One 2010; 5: e9504.
-
(2010)
PLoS One
, vol.5
-
-
Mengshol, J.A.1
Golden-Mason, L.2
Arikawa, T.3
Smith, M.4
Niki, T.5
McWilliams, R.6
-
17
-
-
78649903057
-
Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity
-
McMahan RH, Golden-Mason L, Nishimura MI, McMahon BJ, Kemper M, Allen TM, et al. Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity. J Clin Invest 2010; 120: 4546-4557.
-
(2010)
J Clin Invest
, vol.120
, pp. 4546-4557
-
-
McMahan, R.H.1
Golden-Mason, L.2
Nishimura, M.I.3
McMahon, B.J.4
Kemper, M.5
Allen, T.M.6
-
18
-
-
68849111961
-
Therapeutic potential of targeting BTLA
-
Crawford A, Wherry EJ. Therapeutic potential of targeting BTLA. J Leukoc Biol 2009; 86: 5-8.
-
(2009)
J Leukoc Biol
, vol.86
, pp. 5-8
-
-
Crawford, A.1
Wherry, E.J.2
|