Walnut allergy in peanut-allergic patients: Significance of sequential epitopes of walnut homologous to linear epitopes of ara h 1, 2 and 3 in relation to clinical reactivity

International Archives of Allergy and Immunology

Volumn 157, Issue 3, 2012, Pages 238-245

  Rosenfeld, Leonard ^a   Shreffler, Wayne ^b   Bardina, Ludmilla ^b   Niggemann, SBodo ^a   Wahn, Ulrich ^a   Sampson, Hugh A ^b   Beyer, Kirsten ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Allergen structure; Epitopes; IgE; In vitro tests; Peanut allergy; Walnut allergy

Indexed keywords

ARA H 1 ANTIGEN; ARA H 2 ANTIGEN; ARA H 3 ANTIGEN; FOOD ALLERGEN; IMMUNOGLOBULIN E ANTIBODY; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AMINO ACID SEQUENCE; ANTIGEN BINDING; ANTIGEN RECOGNITION; ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CROSS REACTION; HUMAN; PEANUT ALLERGY; PRIORITY JOURNAL; PROTEIN MICROARRAY; SEQUENCE HOMOLOGY; WALNUT; WALNUT ALLERGY;

2S ALBUMINS, PLANT; ADOLESCENT; ADULT; ALLERGENS; ANTIGENS, PLANT; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; EPITOPE MAPPING; EPITOPES; GLYCOPROTEINS; HUMANS; IMMUNOGLOBULIN E; JUGLANS; NUT HYPERSENSITIVITY; PEANUT HYPERSENSITIVITY; PLANT PROTEINS; PROTEIN ARRAY ANALYSIS; YOUNG ADULT;

EID: 80055023016     PISSN: 10182438     EISSN: 14230097     Source Type: Journal    
DOI: 10.1159/000327841     Document Type: Article

References (32)

1. Sampson HA: Update on food allergy. J Allergy Clin Immunol 2004; 113: 805-819, quiz 820. (Pubitemid 38608586)
2. Sicherer SH, Munoz-Furlong A, Sampson HA: Prevalence of peanut and tree nut allergy in the United States determined by means of a random digit dial telephone survey: A 5-year follow-up study. J Allergy Clin Immunol 2003; 112: 1203-1207. (Pubitemid 37550017)
3. Sicherer SH, Munoz-Furlong A, Godbold JH, Sampson HA: US prevalence of self-reported peanut, tree nut, and sesame allergy: 11-year follow-up. J Allergy Clin Immunol 2010; 125: 1322-1326.
4. Grundy J, Matthews S, Bateman B, Dean T, Arshad SH: Rising prevalence of allergy to peanut in children: Data from 2 sequential cohorts. J Allergy Clin Immunol 2002; 110: 784-789. (Pubitemid 35423183)
5. Tariq SM, Stevens M, Matthews S, Ridout S, Twiselton R, Hide DW: Cohort study of peanut and tree nut sensitisation by age of 4 years. BMJ 1996; 313: 514-517. (Pubitemid 26336132)
6. Bock SA, Munoz-Furlong A, Sampson HA: Fatalities due to anaphylactic reactions to foods. J Allergy Clin Immunol 2001; 107: 191-193. (Pubitemid 32105265)
7. Morisset M, Moneret-Vautrin DA, Kanny G, Guenard L, Beaudouin E, Flabbee J, Hatahet R: Thresholds of clinical reactivity to milk, egg, peanut and sesame in immunoglobulin E-dependent allergies: Evaluation by doubleblind or single-blind placebo-controlled oral challenges. Clin Exp Allergy 2003; 33: 1046-1051. (Pubitemid 36976230)
8. Moneret-Vautrin DA, Kanny G: Update on threshold doses of food allergens: Implications for patients and the food industry. Curr Opin Allergy Clin Immunol 2004; 4: 215-219. (Pubitemid 38685525)
9. Wood RA: The natural history of food allergy. Pediatrics 2003; 111: 1631-1637. (Pubitemid 36676683)
10. Ewan PW: Clinical study of peanut and nut allergy in 62 consecutive patients: New features and associations. BMJ 1996; 312: 1074-1078. (Pubitemid 26125134)
11. Clark AT, Ewan PW: Interpretation of tests for nut allergy in one thousand patients, in relation to allergy or tolerance. Clin Exp Allergy 2003; 33: 1041-1045. (Pubitemid 36976229)
12. Wallowitz M, Peterson WR, Uratsu S, Comstock SS, Dandekar AM, Teuber SS: Jug r 4, a legumin group food allergen from walnut ( Juglans regia cv. Chandler). J Agric Food Chem 2006; 54: 8369-8375. (Pubitemid 44785428)
13. Schocker F, Luttkopf D, Scheurer S, Petersen A, Cistero-Bahima A, Enrique E, San Miguel-Moncin M, Akkerdaas J, van Ree R, Vieths S, Becker WM: Recombinant lipid transfer protein Cor a 8 from hazelnut: A new tool for in vitro diagnosis of potentially severe hazelnut allergy. J Allergy Clin Immunol 2004; 113: 141-147. (Pubitemid 38096174)
14. Roux KH, Teuber SS, Sathe SK: Tree nut allergens. Int Arch Allergy Immunol 2003; 131: 234-244. (Pubitemid 36980756)
15. Rabjohn P, Helm EM, Stanley JS, West CM, Sampson HA, Burks AW, Bannon GA: Molecular cloning and epitope analysis of the peanut allergen Ara h 3. J Clin Invest 1999; 103: 535-542. (Pubitemid 29094054)
16. Burks AW, Williams LW, Helm RM, Connaughton C, Cockrell G, O'Brien T: Identification of a major peanut allergen, Ara h I, in patients with atopic dermatitis and positive peanut challenges. J Allergy Clin Immunol 1991; 88: 172-179.
17. Stanley JS, King N, Burks AW, Huang SK, Sampson H, Cockrell G, Helm RM, West CM, Bannon GA: Identification and mutational analysis of the immunodominant IgE binding epitopes of the major peanut allergen Ara h 2. Arch Biochem Biophys 1997; 342: 244-253. (Pubitemid 27251245)
18. Pinilla C, Martin R, Gran B, Appel JR, Boggiano C, Wilson DB, Houghten RA: Exploring immunological specificity using synthetic peptide combinatorial libraries. Curr Opin Immunol 1999; 11: 193-202. (Pubitemid 29154906)
19. Beyer K, Ellman-Grunther L, Jarvinen KM, Wood RA, Hourihane J, Sampson HA: Measurement of peptide-specific IgE as an additional tool in identifying patients with clinical reactivity to peanuts. J Allergy Clin Immunol 2003; 112: 202-207. (Pubitemid 36819828)
20. Chatchatee P, Jarvinen KM, Bardina L, Beyer K, Sampson HA: Identification of IgE-and IgG-binding epitopes on alpha(s1)-casein: Differences in patients with persistent and transient cow's milk allergy. J Allergy Clin Immunol 2001; 107: 379-383. (Pubitemid 32173919)
21. Shreffler WG, Beyer K, Chu TH, Burks AW, Sampson HA: Microarray immunoassay: Association of clinical history, in vitro IgE function, and heterogeneity of allergenic peanut epitopes. J Allergy Clin Immunol 2004; 113: 776-782. (Pubitemid 38530436)
22. de Leon MP, Glaspole IN, Drew AC, Rolland JM, O'Hehir RE, Suphioglu C: Immunological analysis of allergenic cross-reactivity between peanut and tree nuts. Clin Exp Allergy 2003; 33: 1273-1280. (Pubitemid 37108533)
23. Teuber SS, Jarvis KC, Dandekar AM, Peterson WR, Ansari AA: Identification and cloning of a complementary DNA encoding a vicilin-like proprotein, Jug r 2, from English walnut kernel (Juglans regia) , a major food allergen. J Allergy Clin Immunol 1999; 104: 1311-1320. (Pubitemid 30004996)
24. Shreffler WG, Lencer DA, Bardina L, Sampson HA: IgE and IgG4 epitope mapping by microarray immunoassay reveals the diversity of immune response to the peanut allergen, Ara h 2. J Allergy Clin Immunol 2005; 116: 893-899. (Pubitemid 41400557)
25. Burks AW, Shin D, Cockrell G, Stanley JS, Helm RM, Bannon GA: Mapping and mutational analysis of the IgE-binding epitopes on Ara h 1, a legume vicilin protein and a major allergen in peanut hypersensitivity. Eur J Biochem 1997; 245: 334-339. (Pubitemid 27171255)
26. Maloney JM, Rudengren M, Ahlstedt S, Bock SA, Sampson HA: The use of serum-specific IgE measurements for the diagnosis of peanut, tree nut, and seed allergy. J Allergy Clin Immunol 2008; 122: 145-151.
27. Goetz DW, Whisman BA, Goetz AD: Crossreactivity among edible nuts: Double immunodiffusion, crossed immunoelectrophoresis, and human specific IgE serologic surveys. Ann Allergy Asthma Immunol 2005; 95: 45-52. (Pubitemid 41022772)
28. Barre A, Sordet C, Culerrier R, Rance F, Didier A, Rouge P: Vicilin allergens of peanut and tree nuts (walnut, hazelnut and cashew nut) share structurally related IgE-binding epitopes. Mol Immunol 2008; 45: 1231-1240.
29. Barre A, Borges JP, Culerrier R, Rouge P: Homology modelling of the major peanut allergen Ara h 2 and surface mapping of IgEbinding epitopes. Immunol Lett 2005; 100: 153-158. (Pubitemid 41262013)
30. Barre A, Jacquet G, Sordet C, Culerrier R, Rouge P: Homology modelling and conformational analysis of IgE-binding epitopes of Ara h 3 and other legumin allergens with a cupin fold from tree nuts. Mol Immunol 2007; 44: 3243-3255. (Pubitemid 46610498)
31. Albrecht M, Kuhne Y, Ballmer-Weber BK, Becker WM, Holzhauser T, Lauer I, Reuter A, Randow S, Falk S, Wangorsch A, Lidholm J, Reese G, Vieths S: Relevance of IgE binding to short peptides for the allergenic activity of food allergens. J Allergy Clin Immunol 2009; 124: 328-336, 336.e1-336.e6.
32. Robotham JM, Teuber SS, Sathe SK, Roux KH: Linear IgE epitope mapping of the English walnut (Juglans regia) major food allergen, Jug r 1. J Allergy Clin Immunol 2002; 109: 143-149. (Pubitemid 34112144)