Treatment with the α-glucosidase inhibitor miglitol from the preonset stage in Otsuka Long-Evans Tokushima Fatty rats improves glycemic control and reduces the expression of inflammatory cytokine genes in peripheral leukocytes

Metabolism: Clinical and Experimental

Volumn 60, Issue 11, 2011, Pages 1560-1565

  Mochizuki, Kazuki ^a   Fukaya, Nanae ^a   Tanaka, Yutaro ^a   Fuchigami, Masahiro ^b   Goda, Toshinao ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

^b Sanwa Kagaku Kenkyusho Ltd   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1,5 ANHYDROSORBITOL; GAMMA INTERFERON; GLUCOSE; INTERLEUKIN 6; MESSENGER RNA; MIGLITOL; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD LEVEL; BODY WEIGHT; CONTROLLED STUDY; CYTOKINE RELEASE; FOOD INTAKE; GENE EXPRESSION REGULATION; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; LEUKOCYTE; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OTSUKA LONG EVANS TOKUSHIMA FATTY RAT; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TREATMENT DURATION; TRIACYLGLYCEROL BLOOD LEVEL;

1-DEOXYNOJIRIMYCIN; ALPHA-GLUCOSIDASES; ANIMALS; BLOOD GLUCOSE; CYTOKINES; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; GENE EXPRESSION; HYPOGLYCEMIC AGENTS; INFLAMMATION MEDIATORS; LEUKOCYTES; MALE; PREDIABETIC STATE; RATS; RATS, INBRED OLETF;

EID: 80055022652     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2011.03.010     Document Type: Article

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