High expression of GLT-1 in hippocampal CA3 and dentate gyrus subfields contributes to their inherent resistance to ischemia in rats

Neurochemistry International

Volumn 59, Issue 7, 2011, Pages 1019-1028

  Zhang, Min ^a   Li, Wen Bin ^a,b   Liu, Yi Xian ^a   Liang, Cui Juan ^a   Liu, Li Zhe ^a   Cui, Xin ^a   Gong, Jian Xue ^a   Gong, Shu Juan ^a   Hu, Yu Yan ^a   Xian, Xiao Hui ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b Aging and Cognition Neuroscience Laboratory of Hebei Province   (China)

Author keywords

Astrocyte; Cerebral ischemia; Glial glutamate transporter 1; Hippocampus; Rat

Indexed keywords

VESICULAR GLUTAMATE TRANSPORTER 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN ISCHEMIA; CONTROLLED STUDY; DENTATE GYRUS; DISEASE SEVERITY; DOWN REGULATION; FAR WESTERN BLOTTING; HIPPOCAMPAL CA3 REGION; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; RAT;

ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; BRAIN ISCHEMIA; DENTATE GYRUS; DNA PRIMERS; EXCITATORY AMINO ACID TRANSPORTER 2; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; RATS; RATS, WISTAR;

RATTUS;

EID: 80055005419     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2011.08.023     Document Type: Article

References (34)

1. S.J. An, T.C. Kang, S.K. Park, I.K. Hwang, S.S. Cho, M.H. Chung, and M.H. Won Oxidative DNA damage and alteration of glutamate transporter expressions in the hippocampal Ca1 area immediately after ischemic insult Mol. Cells 13 2002 476 480
2. P. Benquet, C.E. Gee, and U. Gerber Transient brain ischemia: NMDA receptor modulation and delayed neuronal death Med. Sci. (Paris) 24 2008 185 190
3. H. Benveniste, J. Drejer, A. Schousboe, and N.H. Diemer Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis J. Neurochem. 43 1984 1369 1374
4. T. Bruhn, L.M. Levy, M. Nielsen, T. Christensen, F.F. Johansen, and N.H. Diemer Ischemia induced changes in expression of the astrocyte glutamate transporter GLT1 in hippocampus of the rat Neurochem. Int. 37 2000 277 285
5. J.C. Chen, H. Hsu-Chou, J.L. Lu, Y.C. Chiang, H.M. Huang, H.L. Wang, T. Wu, J.J. Liao, and T.S. Yeh Downregulation of the glial glutamate transporter GLT-1 in rat hippocampus and striatum and its modulation by a group III metabotropic glutamate receptor antagonist following transient global forebrain ischemia Neuropharmacology 49 2005 703 714
6. T. Deierborg, T. Wieloch, S. Diano, C.H. Warden, T.L. Horvath, and G. Mattiasson Over expression of UCP2 protects thalamic neurons following global ischemia in the mouse J. Cereb. Blood Flow Metab. 28 2008 1186 1195
7. J.X. Geng, J.S. Cai, M. Zhang, S.Q. Li, X.C. Sun, X.H. Xian, Y.Y. Hu, W.B. Li, and Q.J. Li Antisense oligodeoxynucleotides of glial glutamate transporter-1 inhibits the neuro-protection of cerebral ischemic preconditioning in rats Sheng Li Xue Bao 60 2008 497 503
8. F. Han, N. Shioda, S. Moriguchi, Z.H. Qin, and K. Fukunaga Downregulation of glutamate transporters is associated with elevation in extracellular glutamate concentration following rat microsphere embolism Neurosci. Lett. 430 2008 275 280
9. M. Iwata, S. Inoue, M. Kawaguchi, N. Kurita, T. Horiuchi, M. Nakamura, N. Konishi, and H. Furuya Delta opioid receptors stimulation with [D-Ala2, D-Leu5] enkephalin does not provide neuroprotection in the hippocampus in rats subjected to forebrain ischemia Neurosci. Lett. 414 2007 242 246
10. J.T. Jamison, F. Kayali, J. Rudolph, M. Marshall, S.R. Kimball, and D.J. DeGracia Persistent redistribution of poly-adenylated mRNAs correlates with translation arrest and cell death following global brain ischemia and reperfusion Neuroscience 154 2008 504 520
11. E. Kondratskaya, M.C. Shin, and N. Akaike Neuronal glutamate transporters regulate synaptic transmission in single synapses on CA1 hippocampal neurons Brain Res. Bull. 81 2010 53 60
12. K.P. Lehre, L.M. Levy, O.P. Ottersen, J. Storm-Mathisen, and N.C. Danbolt Differential expression of two glial glutamate transporters in the rat brain: quantitative and immunocytochemical observations J. Neurosci. 3 1995 1835 1853
13. +] coupled L-glutamate transporter purified from rat brain confirms glial cell localization FEBS Lett. 317 1993 79 84
14. G.H. Liao, M. Zhou, S.M. Cheung, J. Galeano, N. Nguyen, M. Baudry, and X.N. Bi Reduced early hypoxic/ischemic brain damage is associated with increased GLT-1 levels in mice expressing mutant (P301L) human tau Brain Res. 1247 2009 159 170
15. H.Q. Liu, W.B. Li, Q.J. Li, M. Zhang, X.C. Sun, R.F. Feng, X.H. Xian, S.Q. Li, J. Qi, and H.G. Zhao Nitric oxide participates in the induction of brain ischemic tolerance via activating ERK1/2 signaling pathways Neurochem. Res. 31 2006 967 974
16. 2+-permeable AMPA receptor channels primes cell death in transient forebrain ischemia Neuron 43 2004 43 55
17. 2+ entry through TRPM7 channels and anoxic neuronal death Cell 115 2003 768 770
18. Y. Oida, M. Shimazawa, K. Imaizumi, and H. Hara Involvement of endoplasmic reticulum stress in the neuronal death induced by transient forebrain ischemia in gerbil Neuroscience 151 2008 111 119
19. Y.B. Ouyang, L.A. Voloboueva, L.J. Xu, and R.G. Giffard Selective dysfunction of hippocampal CA1 astrocytes contributes to delayed neuronal damage after transient forebrain ischemia J. Neurosci. 27 2007 4253 4260
20. Pathmajeyan, M.S., Patel, S.A., Carroll, J.A., Seib, T., Striebel, J.F., Bridges, R.J., Chesebro, B., 2011. Increased excitatory amino acid transport into murine prion protein knockout astrocytes cultured in vitro. Glia [Epub ahead of print].
21. W.A. Pulsinelli, and J.B. Brierley A new model of bilateral hemispheric ischemia in the unanesthetized rat Stroke 10 1979 267 272
22. V.L. Rao, A. Dogan, K.K. Bowen, K.G. Todd, and R.J. Dempsey Antisense knockdown of the glial glutamate transporter GLT-1 exacerbates hippocampal neuronal damage following traumatic injury to rat brain Eur. J. Neurosci. 13 2001 119 128
23. V.L. Rao, A. Dogan, K.G. Todd, K.K. Bowen, B.T. Kim, J.D. Rothstein, and R.J. Dempsey Antisense knockdown of the glial glutamate transporter GLT-1, but not the neuronal glutamate transporter EAAC1, exacerbates transient focal cerebral ischemia-induced neuronal damage in rat brain J. Neurosci. 21 2001 1876 1883
24. C. Romera, O. Hurtado, J. Mallolas, M.P. Pereira, J.R. Morales, A. Romera, J. Serena, J. Vivancos, F. Nombela, P. Lorenzo, I. Lizasoain, and M.A. Moro Ischemic preconditioning reveals that GLT1/EAAT2 glutamate transporter is a novel PPARgamma target gene involved in neuroprotection J. Cereb. Blood Flow Metab. 27 2007 1327 1338
25. J.D. Rothstein, M. Dykes-Hoberg, C.A. Pardo, L.A. Bristol, L. Jin, R.W. Kuncl, Y. Kanai, M.A. Hediger, Y. Wang, J.P. Schielke, and D.F. Welty Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate Neuron 16 1996 675 686
26. J.D. Rothstein, L. Martin, A.I. Levey, M. Dykes-Hoberg, L. Jin, D. Wu, N. Nash, and R.W. Kuncl Localization of neuronal and glial glutamate transporters Neuron 13 1994 713 725
27. R. Schmidt-Kastner, and T.F. Freund Selective vulnerability of the hippocampus in brain ischemia Neuroscience 40 1991 599 636
28. K. Tanaka, K. Watase, T. Manabe, K. Yamada, M. Watanabe, K. Takahashi, H. Iwama, T. Nishikawa, N. Ichihara, T. Kikuchi, S. Okuyama, N. Kawashima, S. Hori, M. Takimoto, and K. Wada Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1 Science 276 1997 1699 1702
29. A. Thümen, A. Behnecke, F. Qadri, E. Bäuml, A. Thümen, C.A. Behnecke, F. Qadri, E. Bäuml, and A. Moser N-methyl-norsalsolinol, a putative dopaminergic neurotoxin, passes through the blood-brain barrier in vivo Neuroreport 13 2002 25 28
30. R. Verma, V. Mishra, D. Sasmal, and R. Raghubir Pharmacological evaluation of glutamate transporter 1 (GLT-1) mediated neuroprotection following cerebral ischemia/reperfusion injury Eur. J. Pharmacol. 638 2010 65 71
31. G.J. Wu, W.F. Chen, C.S. Sung, Y.H. Jean, C.M. Shih, C.Y. Shyu, and Z.H. Wen Preventive effects of intrathecal methylprednisolone administration on spinal cord ischemia in rats: the role of excitatory amino acid metabolizing systems Neuroscience 147 2007 294 303
32. T.H. Yeh, H.M. Hwang, J.J. Chee, T. Wu, A.H. Li, and H.L. Wang Glutamate transporter function of rat hippocampal astrocytes is impaired following the global ischemia Neurobiol. Dis. 18 2005 476 483
33. M. Zhang, W.B. Li, J.X. Geng, Q.J. Li, X.C. Sun, X.H. Xian, J. Qi, and S.Q. Li The upregulation of glial glutamate transporter-1 participates in the induction of brain ischemic tolerance in rats J. Cereb. Blood Flow Metab. 27 2007 1352 1368
34. A.M. Zhou, W.B. Li, Q.J. Li, H.Q. Liu, R.F. Feng, and H.G. Zhao A short cerebral ischemic preconditioning up-regulates adenosine receptors in the hippocampal CA1 region of rats Neurosci. Res. 48 2004 379 404