Association of candidate genes with phenotypic traits relevant to anorexia nervosa

European Eating Disorders Review

Volumn 19, Issue 6, 2011, Pages 487-493

  Root, Tammy L ^b   Szatkiewicz, Jin P ^a   Jonassaint, Charles R ^b   Thornton, Laura M ^a   Pinheiro, Andrea Poyastro ^a   Strober, Michael ^c   Bloss, Cinnamon ^d   Berrettini, Wade ^e   Schork, Nicholas J ^d   Kaye, Walter H ^f   Bergen, Andrew W ^g   Magistretti, Pierre ^h   Brandt, Harry ⁱ   Crawford, Steve ⁱ   Crow, Scott ^j   Fichter, Manfred M ^k   Goldman, David ^l   Halmi, Katherine A ^m   Johnson, Craig ⁿ   Kaplan, Allan S ^o,p,q   Keel, Pamela K ^r   Klump, Kelly L ^s   La Via, Maria ^a   Mitchell, James E ^t,u   Rotondo, Alessandro ^v   Treasure, Janet ^w   Woodside, D Blake ^x,y   Bulik, Cynthia M ^a,z   more..

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g SRI INTERNATIONAL   (United States)

^h University of Lausanne Medical Center   (Switzerland)

ⁱ UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^j UNIVERSITY OF MINNESOTA   (United States)

^k LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^l NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^m WEILL CORNELL MEDICAL COLLEGE   (United States)

ⁿ Eating Recovery Center   (United States)

^o CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

^p UNIVERSITY HEALTH NETWORK   (Canada)

^q UNIVERSITY OF TORONTO   (Canada)

^r FLORIDA STATE UNIVERSITY   (United States)

^s MICHIGAN STATE UNIVERSITY   (United States)

^t NEUROPSYCHIATRIC RESEARCH INSTITUTE   (United States)

^u UND School of Medicine & Health Sciences Southeast Campus   (United States)

^v UNIVERSITY OF PISA   (Italy)

^w KING'S COLLEGE LONDON   (United Kingdom)

^x TORONTO GENERAL HOSPITAL   (Canada)

^y UNIVERSITY OF TORONTO   (Canada)

^z IL   (United States)

more..

Author keywords

association studies; covariates; eating disorders; genetic; personality

Indexed keywords

ADULT; ANOREXIA NERVOSA; ANTICIPATORY ANXIETY; ARTICLE; BODY MASS; BODY WEIGHT; CONTROLLED STUDY; FEMALE; FOLLOW UP; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC TRAIT; GENETIC VARIABILITY; GENOTYPE PHENOTYPE CORRELATION; HUMAN; MAJOR CLINICAL STUDY; MENARCHE; OPTIMISM; PESSIMISM; PHENOTYPE; PSYCHOLOGICAL RATING SCALE; SATISFACTION;

ADULT; AGE FACTORS; ANOREXIA NERVOSA; ANXIETY; BODY IMAGE; BODY MASS INDEX; DRIVE; FEMALE; FOLLOW-UP STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MENARCHE; PERSONAL SATISFACTION; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; YOUNG ADULT;

EID: 80055002817     PISSN: 10724133     EISSN: 10990968     Source Type: Journal    
DOI: 10.1002/erv.1138     Document Type: Article

References (52)

1. Bacanu, S. A., Bulik, C. M., Klump, K. L., Fichter, M. M., Halmi, K. A., Keel, P., et al. (2005). Linkage analysis of anorexia and bulimia nervosa cohorts using selected behavioral phenotypes as quantitative traits or covariates. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 139B, 61-68. (Pubitemid 41552300)
2. Bieling, P. J., Antony, M. M., &, Swinson, R. P., (1998). The State-Trait Anxiety Inventory, Trait version: Structure and content re-examined. Behaviour Research and Therapy, 36, 777-788. (Pubitemid 28339797)
3. Bulik, C. M., Bacanu, S. A., Klump, K. L., Fichter, M. M., Halmi, K. A., Keel, P., et al. (2005). Selection of eating-disorder phenotypes for linkage analysis. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 139, 81-87. (Pubitemid 41552303)
4. Bulik, C. M., Slof-Op't Landt, M. C., van Furth, E. F., &, Sullivan, P. F., (2007). The genetics of anorexia nervosa. Annual Review of Nutrition, 27, 263-275. (Pubitemid 351373358)
5. Bulik, C. M., Sullivan, P. F., Tozzi, F., Furberg, H., Lichtenstein, P., &, Pedersen, N. L., (2006). Prevalence, heritability and prospective risk factors for anorexia nervosa. Archives of General Psychiatry, 63, 305-312. (Pubitemid 43345355)
6. Bulik, C. M., Thornton, L. M., Root, T. L., Pisetsky, E. M., Lichtenstein, P., &, Pedersen, N. L., (2010). Understanding the relation between anorexia nervosa and bulimia nervosa in a Swedish national twin sample. Biological Psychiatry, 67, 71-77.
7. Cardon, L. R., &, Palmer, L. J., (2003). Population stratification and spurious allelic association. Lancet, 361, 598-604. (Pubitemid 36207482)
8. Carter, N. P., (2007). Methods and strategies for analyzing copy number variation using DNA microarrays. Nature Genetics, 39, S16-S21. (Pubitemid 47014471)
9. Cichon, S., Craddock, N., Daly, M., Faraone, S. V., Gejman, P. V., Kelsoe, J., et al. (2009). Genomewide association studies: History, rationale, and prospects for psychiatric disorders. The American Journal of Psychiatry, 166, 540-556.
10. Cloninger, C. R., Svrakic, D. M., &, Przybeck, T. R., (1993). A psychobiological model of temperament and character. Archives of General Psychiatry, 50, 975-990. (Pubitemid 23361478)
11. Corvin, A., Craddock, N., &, Sullivan, P. F., (2010). Genome-wide association studies: A primer. Psychological Medicine, 40, 1063-1077.
12. Davis, C., Kennedy, S., Ravelski, E., &, Dionne, M., (1994). The role of physical activity in the development and maintenance of eating disorders. Psychological Medicine, 24, 957-967.
13. Devlin, B., Bacanu, S. A., Klump, K. L., Bulik, C. M., Fichter, M. M., Halmi, K. A., et al. (2002). Linkage analysis of anorexia nervosa incorporating behavioral covariates. Human Molecular Genetics, 11, 689-696. (Pubitemid 34285140)
14. Efron, B., Tibshirani, R., Storey, J. D., &, Tusher, V., (2001). Empirical Bayes analysis of a microarray experiment. Journal of the American Statistical Association, 96, 1151-1160. (Pubitemid 33695570)
15. Fichter, M. M., Herpertz, S., Quadflieg, N., &, Herpertz-Dahlmann, B., (1998). Structured Interview for Anorexic and Bulimic disorders for DSM-IV and ICD-10: Updated (third) revision. The International Journal of Eating Disorders, 24, 227-249. (Pubitemid 28391686)
16. First, M., Gibbon, M., Spitzer, R., Williams, J., &, Benjamin, L., (1997). User's guide for the structured clinical interview for DSM-IV Axis II personal disorders (SCID-II). Washington, D.C.: Am Psychiatric Press.
17. Frost, R., Marten, P., Lahart, C., &, Rosenblate, R., (1990). The dimensions of perfectionism. Cognitive Therapy and Research, 14, 449-468. (Pubitemid 20377898)
18. Garner, D., Olmsted, M., &, Polivy, J., (1983). The eating disorders inventory: A measure of cognitive-behavioural dimensions of anorexia and bulimia. In, P. Darby, (Ed.), Anorexia nervosa: Recent developments in research. New York: Liss, AR, pp. 173-184.
19. Gershon, E. S., &, Goldin, L. R., (1986). Clinical methods in psychiatric genetics. I. Robustness of genetic marker investigative strategies. Acta Psychiatrica Scandinavica, 74, 113-118. (Pubitemid 16022153)
20. Gill, M., Donohoe, G., &, Corvin, A., (2010). What have the genomics ever done for the psychoses? Psychological Medicine, 40, 529-540.
21. Grice, D. E., Halmi, K. A., Fichter, M. M., Strober, M., Woodside, D. B., Treasure, J. T., et al. (2002). Evidence for a susceptibility gene for anorexia nervosa on chromosome 1. American Journal of Human Genetics, 70, 787-792. (Pubitemid 34177934)
22. Hebebrand, J., &, Bulik, C. M., (2010). Critical appraisal of the provisional DSM-5 criteria for anorexia nervosa and an alternative proposal. The International Journal of Eating Disorders, Nov 15. [Epub ahead of print].
23. Hebebrand, J., Himmelmann, G. W., Heseker, H., Schafer, H., &, Remschmidt, H., (1996). Use of percentiles for the body mass index in anorexia nervosa: Diagnostic, epidemiological, and therapeutic considerations. The International Journal of Eating Disorders, 19, 359-369. (Pubitemid 26123121)
24. Holliday, J., Tchanturia, K., Landau, S., Collier, D., &, Treasure, J., (2005). Is impaired set-shifting an endophenotype of anorexia nervosa? The American Journal of Psychiatry, 162, 2269-2275. (Pubitemid 41740204)
25. Kaye, W. H., Devlin, B., Barbarich, N., Bulik, C. M., Thornton, L. M., Bacanu, S. A., et al. (2004). Genetic analysis of bulimia nervosa: Methods and sample description. The International Journal of Eating Disorders, 35, 556-570. (Pubitemid 38552827)
26. Kaye, W. H., Fudge, J. L., &, Paulus, M., (2009). New insights into symptoms and neurocircuit function of anorexia nervosa. Nature Reviews Neuroscience, 10, 573-584.
27. Kaye, W. H., Lilenfeld, L. R., Berrettini, W. H., Strober, M., Devlin, B., Klump, K. L., et al. (2000). A search for susceptibility loci for anorexia nervosa: Methods and sample description. Biological Psychiatry, 47, 794-803. (Pubitemid 30254052)
28. Klump, K. L., Miller, K. B., Keel, P. K., McGue, M., &, Iacono, W. G., (2001). Genetic and environmental influences on anorexia nervosa syndromes in a population-based twin sample. Psychological Medicine, 31, 737-740. (Pubitemid 32421974)
29. Koronyo-Hamaoui, M., Danziger, Y., Frisch, A., Stein, D., Leor, S., Laufer, N., et al. (2002). Association between anorexia nervosa and the hsKCa3 gene: A family-based and case control study. Molecular Psychiatry, 7, 82-85. (Pubitemid 34087883)
30. Koronyo-Hamaoui, M., Gak, E., Stein, D., Frisch, A., Danziger, Y., Leor, S., et al. (2004). CAG repeat polymorphism within the KCNN3 gene is a significant contributor to susceptibility to anorexia nervosa: A case-control study of female patients and several ethnic groups in the Israeli Jewish population. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 131B, 76-80. (Pubitemid 39458441)
31. Kortegaard, L. S., Hoerder, K., Joergensen, J., Gillberg, C., &, Kyvik, K. O., (2001). A preliminary population-based twin study of self-reported eating disorder. Psychological Medicine, 31, 361-365. (Pubitemid 32166401)
32. Lilenfeld, L. R., Kaye, W. H., Greeno, C. G., Merikangas, K. P., Plotnicov, K., Pollice, C., et al. (1998). A controlled family study of anorexia nervosa and bulimia nervosa: Psychiatric disorders in first-degree relatives and effects of proband comorbidity. Archives of General Psychiatry, 55, 603-610. (Pubitemid 28340347)
33. Lupski, J. R., Reid, J. G., Gonzaga-Jauregui, C., Rio Deiros, D., Chen, D. C., Nazareth, L., et al. (2010). Whole-genome sequencing in a patient with Charcot-Marie-Tooth neuropathy. The New England Journal of Medicine, 362, 1181-1191.
34. Medvedev, P., Stanciu, M., &, Brudno, M., (2009). Computational methods for discovering structural variation with next-generation sequencing. Nature Methods, 6, S13-S20.
35. Nakabayashi, K., Komaki, G., Tajima, A., Ando, T., Ishikawa, M., Nomoto, J., et al. (2009). Identification of novel candidate loci for anorexia nervosa at 1q41 and 11q22 in Japanese by a genome-wide association analysis with microsatellite markers. Journal of Human Genetics, 54, 531-537.
36. Pinheiro, A. P., Bulik, C. M., Thornton, L. M., Sullivan, P. F., Root, T. L., Bloss, C. S., et al. (2010). Association study of 182 candidate genes in anorexia nervosa. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 153B, 1070-1080.
37. Purcell, S., Neale, B., Todd-Brown, K., Thomas, L., Ferreira, M. A. R., Bender, D., et al. (2007). PLINK: A toolset for whole-genome association and population-based linkage analysis. American Journal of Human Genetics, 81, 559-575. (Pubitemid 47330214)
38. R Development Core Team. (2009). R: A language and environment for statistical computing Vienna, Austria.
39. Roach, J. C., Glusman, G., Smit, A. F., Huff, C. D., Hubley, R., Shannon, P. T., et al. (2010). Analysis of genetic inheritance in a family quartet by whole-genome sequencing. Science, 328, 636-639.
40. Roberts, M. E., Tchanturia, K., Stahl, D., Southgate, L., &, Treasure, J., (2007). A systematic review and meta-analysis of set-shifting ability in eating disorders. Psychological Medicine, 37, 1075-1084. (Pubitemid 47209111)
41. Sakurai, T., Amemiya, A., Ishii, M., Matsuzaki, I., Chemelli, R. M., Tanaka, H., et al. (1998). Orexins and orexin receptors: A family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell, 92, 573-585. (Pubitemid 28101119)
42. SAS Institute Inc. (2004). SAS/STATÂ Software: Version 9.1. Cary, NC: SAS Institute, Inc.
43. Slof-Op't Landt, M. C., van Furth, E. F., Meulenbelt, I., Slagboom, P. E., Bartels, M., Boomsma, D. I., et al. (2005). Eating disorders: From twin studies to candidate genes and beyond. Twin Research and Human Genetics, 8, 467-482. (Pubitemid 41499488)
44. Spielberger, C., Gorsuch, R., &, Luchene, R., (1970). The State-Trait Anxiety Inventory: Test manual for Form X. Palo Alto, CA: Consulting Psychologists Press.
45. Stefansson, H., Rujescu, D., Cichon, S., Pietilainen, O. P., Ingason, A., Steinberg, S., et al. (2008). Large recurrent microdeletions associated with schizophrenia. Nature, 455, 232-236.
46. Striegel-Moore, R. H., &, Bulik, C. M., (2007). Risk factors for eating disorders. The American Psychologist, 62, 181-198.
47. Strimmer, K., (2008). Fdrtool: A versatile R package for estimating local and tail area-based false discovery rates. Bioinformatics, 24, 1461-1462. (Pubitemid 351851002)
48. Strober, M., Freeman, R., Lampert, C., Diamond, J., &, Kaye, W., (2000). Controlled family study of anorexia nervosa and bulimia nervosa: Evidence of shared liability and transmission of partial syndromes. The American Journal of Psychiatry, 157, 393-401. (Pubitemid 30145925)
49. Wade, T. D., Bulik, C. M., Neale, M., &, Kendler, K. S., (2000). Anorexia nervosa and major depression: Shared genetic and environmental risk factors. The American Journal of Psychiatry, 157, 469-471. (Pubitemid 30145940)
50. Wang, K., Zhang, H., Bloss, C. S., Duvvuri, V., Kaye, W., Schork, N. J., et al. (2010). A genome-wide association study on common SNPs and rare CNVs in anorexia nervosa. Molecular Psychiatry, [Epub Date 2010/11/16].
51. Zhao, J. H., (2007). Gap: Genetic analysis package. Journal of Statistical Software, 23, 1-18.
52. Zucker, N., Losh, M., Bulik, C. M., LaBar, K., Piven, J., &, Pelphrey, K., (2007). Anorexia nervosa and autism spectrum disorders: Guided inquiry into social cognitive endophenotypes. Psychological Bulletin, 133, 976-1006.