Structural basis for antiviral inhibition of the main protease, 3C, from human enterovirus 93

Journal of Virology

Volumn 85, Issue 20, 2011, Pages 10764-10773

  Costenaro, Lionel ^a,b,f   Kaczmarska, Zuzanna ^a,b   Arnan, Carme ^a,b,g   Janowski, Robert ^a,b   Coutard, Bruno ^c   Sola', Maria ^b   Gorbalenya, Alexander E ^d   Norder, Heléne ^e   Canard, Bruno ^c   Coll, Miquel ^a,b  

^a INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

^b INSTITUT DE BIOLOGIA MOLECULAR DE BARCELONA   (Spain)

^c Centre National de la Recherche Scientifique   (France)

^d LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^e Swedish Institute for Disease Control   (Sweden)

^f UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^g CENTRE FOR GENOMIC REGULATION CRG   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

3C PROTEASE; AG 7404; ANTIVIRUS AGENT; CHYMOTRYPSIN; PROTEINASE; RUPINTRIVIR; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG MECHANISM; DRUG STRUCTURE; ENTEROVIRUS; ENTEROVIRUS 93; ENTEROVIRUS INFECTION; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME DEGRADATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PURIFICATION; VIRUS INHIBITION;

ANTIVIRAL AGENTS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; CYSTEINE ENDOPEPTIDASES; ENTEROVIRUS; ENZYME INHIBITORS; HUMANS; ISOXAZOLES; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PYRROLIDINONES; VIRAL PROTEINS;

ENTEROVIRUS; PICORNAVIRIDAE; POLIOVIRUS; RHINOVIRUS;

EID: 80054991481     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.05062-11     Document Type: Article

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