An active fraction of achyranthes bidentata polypeptides prevents apoptosis induced by serum deprivation in SH-SY5Y cells through activation of PI3K/Akt/Gsk3β pathways

Neurochemical Research

Volumn 36, Issue 11, 2011, Pages 2186-2194

  Shen, Yuntian ^a   Zhang, Qi ^a   Gao, Xiaorong ^a   Ding, Fei ^a  

^a NANTONG UNIVERSITY   (China)

Author keywords

Achyranthes bidentata polypeptides; Active fraction; Akt Gsk3 signaling; Apoptosis; Serum deprivation; SH SY5Y cells

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ACHYRANTHES BIDENTATA EXTRACT; CASPASE 3; GLYCOGEN SYNTHASE KINASE 3BETA; PHOSPHATIDYLINOSITOL 3 KINASE; POLYPEPTIDE; PROTEIN BAD; PROTEIN BAK; PROTEIN BAX; PROTEIN BID; PROTEIN KINASE B; SERINE; TETRAZOLIUM;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL DENSITY; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ISOLATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; NEUROTOXICITY; NICK END LABELING; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ACHYRANTHES; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CELL LINE, TUMOR; CELL SURVIVAL; CULTURE MEDIA, SERUM-FREE; GLYCOGEN SYNTHASE KINASE 3; HUMANS; PEPTIDES; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION;

ACHYRANTHES BIDENTATA;

EID: 80054971068     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-011-0543-x     Document Type: Article

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