Achyranthes bidentata polypeptides confer neuroprotection through inhibition of reactive oxygen species production, bax expression, and mitochondrial dysfunction induced by overstimulation of N-methyl-D-aspartate receptors

Journal of Neuroscience Research

Volumn 88, Issue 3, 2010, Pages 669-676

  Shen, Hongmei ^a   Yuan, Ying ^a   Ding, Fei ^a   Hu, Nan ^a   Liu, Jie ^a   Gu, Xiaosong ^a  

^a NANTONG UNIVERSITY   (China)

Author keywords

Achyranthes bidentata polypeptides; Middle cerebral artery occlusion; Mitochondrial apoptosis pathway; N methyl D aspartate receptors

Indexed keywords

ACHYRANTHES BIDENTATA POLYPEPTIDE; CASPASE 3; DICHLOROFLUORESCEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; POLYPEPTIDE; PROTEIN BAX; REACTIVE OXYGEN METABOLITE; RHODAMINE 123; UNCLASSIFIED DRUG;

ACHYRANTHES; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INFARCTION; BRAIN ISCHEMIA; CELL DEATH; COLORIMETRY; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME ASSAY; FLUORESCENCE; HIPPOCAMPUS; IN VIVO STUDY; ISCHEMIA; MALE; MIDDLE CEREBRAL ARTERY; MITOCHONDRIAL MEMBRANE POTENTIAL; NERVE CELL CULTURE; NEUROLOGIC DISEASE; NEUROPROTECTION; NONHUMAN; OCCLUSIVE CEREBROVASCULAR DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; STAINING; WESTERN BLOTTING;

ACHYRANTHES; ANIMALS; BCL-2-ASSOCIATED X PROTEIN; BRAIN; CASPASE 3; CELL DEATH; CELLS, CULTURED; HIPPOCAMPUS; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MITOCHONDRIA; NEUROPROTECTIVE AGENTS; PEPTIDES; PHYTOTHERAPY; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RECEPTORS, N-METHYL-D-ASPARTATE; REPERFUSION INJURY;

EID: 73949089139     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22221     Document Type: Article

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