-
1
-
-
33748093767
-
Linking oncogenic pathways with therapeutic opportunities
-
Bild AH, Potti A, Nevins JR. Linking oncogenic pathways with therapeutic opportunities. Nat Rev Cancer 2006; 6:735-741.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 735-741
-
-
Bild, A.H.1
Potti, A.2
Nevins, J.R.3
-
2
-
-
34249663294
-
Analyzing gene expression data in terms of gene sets: Methodological issues
-
Goeman JJ, Buhlmann P. Analyzing gene expression data in terms of gene sets: methodological issues. Bioinformatics 2007; 23:980-987.
-
(2007)
Bioinformatics
, vol.23
, pp. 980-987
-
-
Goeman, J.J.1
Buhlmann, P.2
-
3
-
-
29244448340
-
Microarray data analysis: From disarray to consolidation and consensus
-
Allison DB, Cui X, Page GP, Sabripour M. Microarray data analysis: from disarray to consolidation and consensus. Nat Rev Genet 2006; 7:55-65.
-
(2006)
Nat. Rev. Genet.
, vol.7
, pp. 55-65
-
-
Allison, D.B.1
Cui, X.2
Page, G.P.3
Sabripour, M.4
-
4
-
-
55749115981
-
A genomic approach to identify molecular pathways associated with chemotherapy resistance
-
Riedel RF, Porrello A, Pontzer E, Chenette EJ, Hsu DS, Balakumaran B, et al. A genomic approach to identify molecular pathways associated with chemotherapy resistance. Mol Cancer Ther 2008; 7:3141-3149.
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 3141-3149
-
-
Riedel, R.F.1
Porrello, A.2
Pontzer, E.3
Chenette, E.J.4
Hsu, D.S.5
Balakumaran, B.6
-
5
-
-
77952697081
-
Chemotherapeutic drug susceptibility associated SNPs are enriched in expression quantitative trait loci
-
USA
-
Gamazon ER, Huang RS, Cox NJ, Dolan ME. Chemotherapeutic drug susceptibility associated SNPs are enriched in expression quantitative trait loci. Proc Natl Acad Sci USA 2010; 107:9287-9292.
-
(2010)
Proc. Natl. Acad. Sci.
, vol.107
, pp. 9287-9292
-
-
Gamazon, E.R.1
Huang, R.S.2
Cox, N.J.3
Dolan, M.E.4
-
6
-
-
0036682041
-
Phase III study of gemcitabine in combination with fluorouracil versus gemcitabine alone in patients with advanced pancreatic carcinoma: Eastern cooperative oncology group trial E2297
-
Berlin JD, Catalano P, Thomas JP, Kugler JW, Haller DG, Benson AB 3rd. Phase III study of gemcitabine in combination with fluorouracil versus gemcitabine alone in patients with advanced pancreatic carcinoma: Eastern cooperative oncology group trial E2297. J Clin Oncol 2002; 20: 3270-3275.
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 3270-3275
-
-
Berlin, J.D.1
Catalano, P.2
Thomas, J.P.3
Kugler, J.W.4
Haller, D.G.5
Benson III, A.B.6
-
7
-
-
33745294373
-
High-dose cytosine arabinoside in the treatment of acute myeloid leukemia: Review of three randomized trials
-
Kern W, Estey EH. High-dose cytosine arabinoside in the treatment of acute myeloid leukemia: Review of three randomized trials. Cancer 2006; 107:116-124.
-
(2006)
Cancer
, vol.107
, pp. 116-124
-
-
Kern, W.1
Estey, E.H.2
-
8
-
-
0023783698
-
Comparison of the cellular pharmacokinetics and toxicity of 2 2-difluorodeoxycytidine and 1- beta-D-arabinofuranosylcytosine
-
Heinemann V, Hertel LW, Grindey GB, Plunkett W. Comparison of the cellular pharmacokinetics and toxicity of 2',2'-difluorodeoxycytidine and 1- beta-D-arabinofuranosylcytosine. Cancer Res 1988; 48:4024-4031.
-
(1988)
Cancer Res.
, vol.48
, pp. 4024-4031
-
-
Heinemann, V.1
Hertel, L.W.2
Grindey, G.B.3
Plunkett, W.4
-
9
-
-
0021953877
-
Cytosine arabinoside transport and metabolism in acute leukemias and T cell lymphoblastic lymphoma
-
Wiley JS, Taupin J, Jamieson GP, Snook M, Sawyer WH, Finch LR. Cytosine arabinoside transport and metabolism in acute leukemias and T cell lymphoblastic lymphoma. J Clin Invest 1985; 75:632-642.
-
(1985)
J. Clin. Invest.
, vol.75
, pp. 632-642
-
-
Wiley, J.S.1
Taupin, J.2
Jamieson, G.P.3
Snook, M.4
Sawyer, W.H.5
Finch, L.R.6
-
10
-
-
33646023117
-
An introduction to ROC analysis
-
Fawcett T. An introduction to ROC analysis. Pattern Recognition Letters 2006; 27:861-874.
-
(2006)
Pattern Recognition Letters
, vol.27
, pp. 861-874
-
-
Fawcett, T.1
-
11
-
-
25844483748
-
In focus: Advanced pancreatic cancer
-
Kindler HL. In focus: advanced pancreatic cancer. Clin Adv Hematol Oncol 2005; 3:420-422.
-
(2005)
Clin. Adv. Hematol. Oncol.
, vol.3
, pp. 420-422
-
-
Kindler, H.L.1
-
12
-
-
0022339052
-
Treatment of malignant hemopathies with aracytine in low doses analysis of 159 cases
-
Castaigne S, Tilly H, Sigaux F, Solal Celigny P, Bordessoule D, Briere J, et al. Treatment of malignant hemopathies with aracytine in low doses. Analysis of 159 cases. Nouv Rev Fr Hematol 1985; 27:377-382.
-
(1985)
Nouv. Rev. Fr. Hematol.
, vol.27
, pp. 377-382
-
-
Castaigne, S.1
Tilly, H.2
Sigaux, F.3
Solal Celigny, P.4
Bordessoule, D.5
Briere, J.6
-
13
-
-
0034937432
-
Proliferative activity of leukaemic blasts and cytosine arabinoside pharmacodynamics are associated with cytogenetically defined prognostic subgroups in acute myeloid leukaemia
-
Braess J, Jahns-Streubel G, Schoch C, Haase D, Haferlach T, Fiegl M, et al. Proliferative activity of leukaemic blasts and cytosine arabinoside pharmacodynamics are associated with cytogenetically defined prognostic subgroups in acute myeloid leukaemia. Br J Haematol 2001; 113:975-982.
-
(2001)
Br. J. Haematol.
, vol.113
, pp. 975-982
-
-
Braess, J.1
Jahns-Streubel, G.2
Schoch, C.3
Haase, D.4
Haferlach, T.5
Fiegl, M.6
-
14
-
-
0035135876
-
Patients with de novo acute myeloid leukaemia and complex karyotype aberrations show a poor prognosis despite intensive treatment: A study of 90 patients
-
Schoch C, Haferlach T, Haase D, Fonatsch C, Loffler H, Schlegelberger B, et al. Patients with de novo acute myeloid leukaemia and complex karyotype aberrations show a poor prognosis despite intensive treatment: a study of 90 patients. Br J Haematol 2001; 112:118-126.
-
(2001)
Br. J. Haematol.
, vol.112
, pp. 118-126
-
-
Schoch, C.1
Haferlach, T.2
Haase, D.3
Fonatsch, C.4
Loffler, H.5
Schlegelberger, B.6
-
15
-
-
33745686698
-
Cellular pharmacology of gemcitabine
-
Mini E, Nobili S, Caciagli B, Landini I, Mazzei T. Cellular pharmacology of gemcitabine. Ann Oncol 2006; 17 (Suppl 5):v7-v12.
-
(2006)
Ann. Oncol.
, vol.17
, Issue.5
-
-
Mini, E.1
Nobili, S.2
Caciagli, B.3
Landini, I.4
Mazzei, T.5
-
16
-
-
23744495336
-
CN-II expression predicts survival in patients receiving gemcitabine for advanced non-small cell lung cancer
-
Seve P, Mackey JR, Isaac S, Tredan O, Souquet PJ, Perol M, et al. cN-II expression predicts survival in patients receiving gemcitabine for advanced non-small cell lung cancer. Lung Cancer 2005; 49:363-370.
-
(2005)
Lung Cancer
, vol.49
, pp. 363-370
-
-
Seve, P.1
Mackey, J.R.2
Isaac, S.3
Tredan, O.4
Souquet, P.J.5
Perol, M.6
-
17
-
-
12144285914
-
Ribonucleotide reductase messenger RNA expression and survival in gemcitabine/cisplatin-treated advanced non-small cell lung cancer patients
-
Rosell R, Danenberg KD, Alberola V, Bepler G, Sanchez JJ, Camps C, et al. Ribonucleotide reductase messenger RNA expression and survival in gemcitabine/cisplatin-treated advanced non-small cell lung cancer patients. Clin Cancer Res 2004; 10:1318-1325.
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 1318-1325
-
-
Rosell, R.1
Danenberg, K.D.2
Alberola, V.3
Bepler, G.4
Sanchez, J.J.5
Camps, C.6
-
18
-
-
33750440839
-
Micro-array analysis of resistance for gemcitabine results in increased expression of ribonucleotide reductase subunits
-
Smid K, Bergman AM, Eijk PP, Veerman G, van Haperen VW, van den Ijssel P, et al. Micro-array analysis of resistance for gemcitabine results in increased expression of ribonucleotide reductase subunits. Nucleosides Nucleotides Nucleic Acids 2006; 25:1001-1007.
-
(2006)
Nucleosides Nucleotides Nucleic Acids
, vol.25
, pp. 1001-1007
-
-
Smid, K.1
Bergman, A.M.2
Eijk, P.P.3
Veerman, G.4
Van Haperen, V.W.5
Van Den Ijssel, P.6
-
19
-
-
0026758498
-
The clinical pharmacology of 6-mercaptopurine
-
Lennard L. The clinical pharmacology of 6-mercaptopurine. Eur J Clin Pharmacol 1992; 43:329-339.
-
(1992)
Eur. J. Clin. Pharmacol.
, vol.43
, pp. 329-339
-
-
Lennard, L.1
-
20
-
-
33645119580
-
Thiopurine S-methyltransferase pharmacogenetics: Insights challenges and future directions
-
Wang L, Weinshilboum R. Thiopurine S-methyltransferase pharmacogenetics: insights, challenges and future directions. Oncogene 2006; 25:1629-1638.
-
(2006)
Oncogene
, vol.25
, pp. 1629-1638
-
-
Wang, L.1
Weinshilboum, R.2
-
21
-
-
0042830383
-
Thiopurine S-methyltransferase TPMT genotype does not predict adverse drug reactions to thiopurine drugs in patients with inflammatory bowel disease
-
Gearry RB, Barclay ML, Burt MJ, Collett JA, Chapman BA, Roberts RL, Kennedy MA. Thiopurine S-methyltransferase (TPMT) genotype does not predict adverse drug reactions to thiopurine drugs in patients with inflammatory bowel disease. Aliment Pharmacol Ther 2003; 18:395-400.
-
(2003)
Aliment. Pharmacol. Ther.
, vol.18
, pp. 395-400
-
-
Gearry, R.B.1
Barclay, M.L.2
Burt, M.J.3
Collett, J.A.4
Chapman, B.A.5
Roberts, R.L.6
Kennedy, M.A.7
-
22
-
-
52049100798
-
Gemcitabine and cytosine arabinoside cytotoxicity: Association with lymphoblastoid cell expression
-
Li L, Fridley B, Kalari K, Jenkins G, Batzler A, Safgren S, et al. Gemcitabine and cytosine arabinoside cytotoxicity: association with lymphoblastoid cell expression. Cancer Res 2008; 68:7050-7058.
-
(2008)
Cancer Res.
, vol.68
, pp. 7050-7058
-
-
Li, L.1
Fridley, B.2
Kalari, K.3
Jenkins, G.4
Batzler, A.5
Safgren, S.6
-
23
-
-
78649580562
-
Ecto-50-nucleotidase and thiopurine cellular circulation: Association with cytotoxicity
-
Li F, Fridley BL, Matimba A, Kalari KR, Pelleymounter L, Moon I, et al. Ecto-50-nucleotidase and thiopurine cellular circulation: association with cytotoxicity. Drug Metab Dispos 2010; 38:2329-2338.
-
(2010)
Drug. Metab. Dispos.
, vol.38
, pp. 2329-2338
-
-
Li, F.1
Fridley, B.L.2
Matimba, A.3
Kalari, K.R.4
Pelleymounter, L.5
Moon, I.6
-
27
-
-
10844290766
-
A model-based background adjustment for oligobucleotide expression arrays
-
Wu Z, Irizarry R, Gentleman R, Martinez-Murillo F, Spencer F. A model-based background adjustment for oligobucleotide expression arrays. J Am Statistical Association 2004; 99:909-917.
-
(2004)
J. Am. Statistical Association
, vol.99
, pp. 909-917
-
-
Wu, Z.1
Irizarry, R.2
Gentleman, R.3
Martinez-Murillo, F.4
Spencer, F.5
-
28
-
-
0037316303
-
A comparison of normalization methods for high density oligonucleotide array data based on variance and bias
-
Bolstad BM, Irizarry RA, Astrand M, Speed TP. A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics 2003; 19:185-193.
-
(2003)
Bioinformatics
, vol.19
, pp. 185-193
-
-
Bolstad, B.M.1
Irizarry, R.A.2
Astrand, M.3
Speed, T.P.4
-
30
-
-
77958614226
-
Self-contained gene-set analysis of expression data: An evaluation of existing and novel methods
-
Fridley BL, Jenkins GD, Biernacka JM. Self-contained gene-set analysis of expression data: an evaluation of existing and novel methods. PLoS One 2010; 5:e12693.
-
(2010)
PLoS One
, vol.5
-
-
Fridley, B.L.1
Jenkins, G.D.2
Biernacka, J.M.3
-
31
-
-
70450189297
-
Gemcitabine and arabinosylcytosin pharmacogenomics: Genome-wide association and drug response biomarkers
-
Li L, Fridley BL, Kalari K, Jenkins G, Batzler A, Weinshilboum RM, Wang L. Gemcitabine and arabinosylcytosin pharmacogenomics: genome-wide association and drug response biomarkers. PLoS One 2009; 4: e7765.
-
(2009)
PLoS One
, vol.4
-
-
Li, L.1
Fridley, B.L.2
Kalari, K.3
Jenkins, G.4
Batzler, A.5
Weinshilboum, R.M.6
Wang, L.7
-
32
-
-
65649124922
-
Proteasome regulators: Activators and inhibitors
-
Huang L, Chen CH. Proteasome regulators: activators and inhibitors. Curr Med Chem 2009; 16:931-939.
-
(2009)
Curr. Med. Chem.
, vol.16
, pp. 931-939
-
-
Huang, L.1
Chen, C.H.2
-
33
-
-
73149111772
-
Identification of survival genes in human glioblastoma cells by small interfering RNA screening
-
Thaker NG, Zhang F, McDonald PR, Shun TY, Lewen MD, Pollack IF, Lazo JS. Identification of survival genes in human glioblastoma cells by small interfering RNA screening. Mol Pharmacol 2009; 76:1246-1255.
-
(2009)
Mol. Pharmacol.
, vol.76
, pp. 1246-1255
-
-
Thaker, N.G.1
Zhang, F.2
McDonald, P.R.3
Shun, T.Y.4
Lewen, M.D.5
Pollack, I.F.6
Lazo, J.S.7
-
34
-
-
37549024231
-
Thiopurines in current medical practice: Molecular mechanisms and contributions to therapy-related cancer
-
Karran P, Attard N. Thiopurines in current medical practice: molecular mechanisms and contributions to therapy-related cancer. Nat Rev Cancer 2008; 8:24-36.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 24-36
-
-
Karran, P.1
Attard, N.2
-
35
-
-
0036451578
-
Role of MRP4 and MRP5 in biology and chemotherapy
-
Sampath J, Adachi M, Hatse S, Naesens L, Balzarini J, Flatley RM, et al. Role of MRP4 and MRP5 in biology and chemotherapy. AAPS PharmSci 2002; 4:E14.
-
(2002)
AAPS PharmSci.
, vol.4
-
-
Sampath, J.1
Adachi, M.2
Hatse, S.3
Naesens, L.4
Balzarini, J.5
Flatley, R.M.6
-
36
-
-
0242401840
-
The crystal structure of AMP-bound PDE4 suggests a mechanism for phosphodiesterase catalysis
-
Huai Q, Colicelli J, Ke H. The crystal structure of AMP-bound PDE4 suggests a mechanism for phosphodiesterase catalysis. Biochemistry 2003; 42:13220-13226.
-
(2003)
Biochemistry
, vol.42
, pp. 13220-13226
-
-
Huai, Q.1
Colicelli, J.2
Ke, H.3
-
37
-
-
0342313502
-
Identification of cyclic AMPphosphodiesterase variants from the PDE4D gene expressed in human peripheral mononuclear cells
-
Nemoz G, Zhang R, Sette C, Conti M. Identification of cyclic AMPphosphodiesterase variants from the PDE4D gene expressed in human peripheral mononuclear cells. FEBS Lett 1996; 384:97-102.
-
(1996)
FEBS Lett.
, vol.384
, pp. 97-102
-
-
Nemoz, G.1
Zhang, R.2
Sette, C.3
Conti, M.4
-
39
-
-
70649113052
-
Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy
-
Ross CJ, Katzov-Eckert H, Dube MP, Brooks B, Rassekh SR, Barhdadi A, et al. Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy. Nat Genet 2009; 41:1345-1349.
-
(2009)
Nat. Genet.
, vol.41
, pp. 1345-1349
-
-
Ross, C.J.1
Katzov-Eckert, H.2
Dube, M.P.3
Brooks, B.4
Rassekh, S.R.5
Barhdadi, A.6
|