메뉴 건너뛰기




Volumn 85, Issue 20, 2011, Pages 10542-10553

A neonatal Fc receptor-targeted mucosal vaccine strategy effectively induces HIV-1 antigen-specific immunity to genital infection

Author keywords

[No Author keywords available]

Indexed keywords

CPG OLIGODEOXYNUCLEOTIDE; FC RECEPTOR; GAG FC PROTEIN; GAG PROTEIN; HYBRID PROTEIN; NEONATAL FC RECEPTOR; UNCLASSIFIED DRUG;

EID: 80054967594     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.05441-11     Document Type: Article
Times cited : (106)

References (52)
  • 1
    • 0030001674 scopus 로고    scopus 로고
    • Immunological memory and protective immunity: understanding their relation
    • Ahmed, R., and D. Gray. 1996. Immunological memory and protective immunity: understanding their relation. Science 272:54-60.
    • (1996) Science , vol.272 , pp. 54-60
    • Ahmed, R.1    Gray, D.2
  • 2
    • 1642381854 scopus 로고    scopus 로고
    • Immunobiology of mucosal HIV infection and the basis for development of a new generation of mucosal AIDS vaccines
    • Belyakov, I. M., and J. A. Berzofsky. 2004. Immunobiology of mucosal HIV infection and the basis for development of a new generation of mucosal AIDS vaccines. Immunity 20:247-253.
    • (2004) Immunity , vol.20 , pp. 247-253
    • Belyakov, I.M.1    Berzofsky, J.A.2
  • 3
    • 0037073930 scopus 로고    scopus 로고
    • Maintenance of serological memory by polyclonal activation of human memory B cells
    • Bernasconi, N. L., E. E. Traggiai, and A. Lanzavecchia. 2002. Maintenance of serological memory by polyclonal activation of human memory B cells. Science 298:2199-2202.
    • (2002) Science , vol.298 , pp. 2199-2202
    • Bernasconi, N.L.1    Traggiai, E.E.2    Lanzavecchia, A.3
  • 4
    • 3042795848 scopus 로고    scopus 로고
    • Pulmonary delivery of an erythropoietin Fc fusion protein in non-human primates through an immunoglobulin transport pathway
    • Bitonti, A. J., et al. 2004. Pulmonary delivery of an erythropoietin Fc fusion protein in non-human primates through an immunoglobulin transport pathway. Proc. Natl. Acad. Sci. U. S. A. 101:9763-9768.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 9763-9768
    • Bitonti, A.J.1
  • 5
    • 33645087653 scopus 로고    scopus 로고
    • Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses
    • Boscardin, S. B., et al. 2006. Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses. J. Exp. Med. 203:599-606.
    • (2006) J. Exp. Med. , vol.203 , pp. 599-606
    • Boscardin, S.B.1
  • 6
    • 57449088402 scopus 로고    scopus 로고
    • Introduction: back to basics: mucosal immunity and novel HIV vaccine concepts
    • Broliden, K., A. T. Haase, S. K. Ahuja, G. M. Shearer, and J. Andersson. 2009. Introduction: back to basics: mucosal immunity and novel HIV vaccine concepts. J. Intern. Med. 265:5-17.
    • (2009) J. Intern. Med. , vol.265 , pp. 5-17
    • Broliden, K.1    Haase, A.T.2    Ahuja, S.K.3    Shearer, G.M.4    Andersson, J.5
  • 7
    • 0028051652 scopus 로고
    • Crystal structure at 2,2 A resolution of the MHC-related neonatal Fc receptor
    • Burmeister, W. P., L. N. Gastinel, N. E. Simister, M. L. Blum, and P. J. Bjorkman. 1994. Crystal structure at 2.2 A resolution of the MHC-related neonatal Fc receptor. Nature 372:336-343.
    • (1994) Nature , vol.372 , pp. 336-343
    • Burmeister, W.P.1    Gastinel, L.N.2    Simister, N.E.3    Blum, M.L.4    Bjorkman, P.J.5
  • 8
    • 0028907457 scopus 로고
    • The affinity of IgG antibodies to gag p24 and p17 in HIV-1-infected patients correlates with disease progression
    • Chargelegue, D., C. M. Stanley, C. M. O'Toole, B. T. Colvin, and M. W. Steward. 1995. The affinity of IgG antibodies to gag p24 and p17 in HIV-1-infected patients correlates with disease progression. Clin. Exp. Immunol. 99:175-181.
    • (1995) Clin. Exp. Immunol. , vol.99 , pp. 175-181
    • Chargelegue, D.1    Stanley, C.M.2    O'Toole, C.M.3    Colvin, B.T.4    Steward, M.W.5
  • 9
    • 60949098815 scopus 로고    scopus 로고
    • Mucosal immunity and protection against HIV/SIV infection: strategies and challenges for vaccine design
    • Demberg, T., and M. Robert-Guroff. 2009. Mucosal immunity and protection against HIV/SIV infection: strategies and challenges for vaccine design. Int. Rev. Immunol. 28:20-48.
    • (2009) Int. Rev. Immunol. , vol.28 , pp. 20-48
    • Demberg, T.1    Robert-Guroff, M.2
  • 10
    • 0032741975 scopus 로고    scopus 로고
    • Bidirectional FcRn-dependent IgG transport in a polarized human intestinal epithelial cell line
    • Dickinson, B. L., et al. 1999. Bidirectional FcRn-dependent IgG transport in a polarized human intestinal epithelial cell line. J. Clin. Invest. 104:903-911.
    • (1999) J. Clin. Invest. , vol.104 , pp. 903-911
    • Dickinson, B.L.1
  • 11
    • 33947394423 scopus 로고    scopus 로고
    • + T cell memory by promoting the generation of IL-7Rα-expressing cells
    • + T cell memory by promoting the generation of IL-7Rα-expressing cells. J. Exp. Med. 204:547-557.
    • (2007) J. Exp. Med. , vol.204 , pp. 547-557
    • Dooms, H.1    Wolslegel, K.2    Lin, P.3    Abbas, A.K.4
  • 12
    • 0023897194 scopus 로고
    • The binding site for C1q on IgG
    • Duncan, A. R., and G. Winter. 1988. The binding site for C1q on IgG. Nature 332:738-740.
    • (1988) Nature , vol.332 , pp. 738-740
    • Duncan, A.R.1    Winter, G.2
  • 13
    • 0034958413 scopus 로고    scopus 로고
    • Antibody from patients with acute human immunodeficiency virus (HIV) infection inhibits primary strains of HIV type 1 in the presence of natural-killer effector cells
    • Forthal, D. N., G. Landucci, and E. S. Daar. 2001. Antibody from patients with acute human immunodeficiency virus (HIV) infection inhibits primary strains of HIV type 1 in the presence of natural-killer effector cells. J. Virol. 75:6953-6961.
    • (2001) J. Virol. , vol.75 , pp. 6953-6961
    • Forthal, D.N.1    Landucci, G.2    Daar, E.S.3
  • 14
    • 77955418027 scopus 로고    scopus 로고
    • Vaccine-induced IgG2 anti-HIV p24 is associated with control of HIV in patients with a 'high-affinity' FcgammaRIIa genotype
    • French, M. A., et al. 2010. Vaccine-induced IgG2 anti-HIV p24 is associated with control of HIV in patients with a 'high-affinity' FcgammaRIIa genotype. AIDS 24:1983-1990.
    • (2010) AIDS , vol.24 , pp. 1983-1990
    • French, M.A.1
  • 15
    • 0031899819 scopus 로고    scopus 로고
    • Long-term immunity and protection against herpes simplex virus type 2 in the murine female genital tract after mucosal but not systemic immunization
    • Gallichan, W. S., and K. L. Rosenthal. 1998. Long-term immunity and protection against herpes simplex virus type 2 in the murine female genital tract after mucosal but not systemic immunization. J. Infect. Dis. 177:1155-1161.
    • (1998) J. Infect. Dis. , vol.177 , pp. 1155-1161
    • Gallichan, W.S.1    Rosenthal, K.L.2
  • 16
    • 0029927482 scopus 로고    scopus 로고
    • Abnormally short serum half-lives of IgG in beta 2-microglobulin-deficient mice
    • Ghetie, V., et al. 1996. Abnormally short serum half-lives of IgG in beta 2-microglobulin-deficient mice. Eur. J. Immunol. 26:690-696.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 690-696
    • Ghetie, V.1
  • 17
    • 21044443872 scopus 로고    scopus 로고
    • Characterization of human immunodeficiency virus Gag-specific gamma interferon-expressing cells following protective mucosal immunization with alphavirus replicon particles
    • Gupta, S., et al. 2005. Characterization of human immunodeficiency virus Gag-specific gamma interferon-expressing cells following protective mucosal immunization with alphavirus replicon particles. J. Virol. 79:7135-7145.
    • (2005) J. Virol. , vol.79 , pp. 7135-7145
    • Gupta, S.1
  • 18
    • 79551578453 scopus 로고    scopus 로고
    • Early events in sexual transmission of HIV and SIV and opportunities for interventions
    • Haase, A. T. 2011. Early events in sexual transmission of HIV and SIV and opportunities for interventions. Annu. Rev. Med. 62:127-139.
    • (2011) Annu. Rev. Med. , vol.62 , pp. 127-139
    • Haase, A.T.1
  • 19
    • 61949216736 scopus 로고    scopus 로고
    • Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge
    • Hansen, S. G., et al. 2009. Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge. Nat. Med. 15:293-299.
    • (2009) Nat. Med. , vol.15 , pp. 293-299
    • Hansen, S.G.1
  • 20
    • 53349167095 scopus 로고    scopus 로고
    • FAs receptor expression in germinal-center B cells is essential for T and B lymphocyte homeostasis
    • Hao, Z., et al. 2008. FAs receptor expression in germinal-center B cells is essential for T and B lymphocyte homeostasis. Immunity 29:615-627.
    • (2008) Immunity , vol.29 , pp. 615-627
    • Hao, Z.1
  • 21
    • 0029856774 scopus 로고    scopus 로고
    • Increased clearance of IgG in mice that lack beta 2-microglobulin: possible protective role of FcRn
    • Israel, E. J., D. F. Wilsker, K. C. Hayes, D. Schoenfeld, and N. E. Simister. 1996. Increased clearance of IgG in mice that lack beta 2-microglobulin: possible protective role of FcRn. Immunology 89:573-578.
    • (1996) Immunology , vol.89 , pp. 573-578
    • Israel, E.J.1    Wilsker, D.F.2    Hayes, K.C.3    Schoenfeld, D.4    Simister, N.E.5
  • 22
    • 0029891262 scopus 로고    scopus 로고
    • The protection receptor for IgG catabolism is the beta2-microglobulin-containing neonatal intestinal transport receptor
    • Junghans, R. P., and C. L. Anderson. 1996. The protection receptor for IgG catabolism is the beta2-microglobulin-containing neonatal intestinal transport receptor. Proc. Natl. Acad. Sci. U. S. A. 93:5512-5516.
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 5512-5516
    • Junghans, R.P.1    Anderson, C.L.2
  • 23
    • 33846101731 scopus 로고    scopus 로고
    • + T-cell responses to different HIV proteins have discordant associations with viral load
    • + T-cell responses to different HIV proteins have discordant associations with viral load. Nat. Med. 13:46-53.
    • (2007) Nat. Med. , vol.13 , pp. 46-53
    • Kiepiela, P.1
  • 24
    • 0028021594 scopus 로고
    • Localization of the site of the murine IgG1 molecule that is involved in binding to the murine intestinal Fc receptor
    • Kim, J. K., M. F. Tsen, V. Ghetie, and E. S. Ward. 1994. Localization of the site of the murine IgG1 molecule that is involved in binding to the murine intestinal Fc receptor. Eur. J. Immunol. 24:2429-2434.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 2429-2434
    • Kim, J.K.1    Tsen, M.F.2    Ghetie, V.3    Ward, E.S.4
  • 25
    • 2642702611 scopus 로고    scopus 로고
    • Increasing immunogenicity of antigens fuses to Ig-binding proteins by cell surface targeting
    • Léonetti, M., et al. 1998. Increasing immunogenicity of antigens fuses to Ig-binding proteins by cell surface targeting. J. Immunol. 160:3820-3827.
    • (1998) J. Immunol. , vol.160 , pp. 3820-3827
    • Léonetti, M.1
  • 26
    • 79952724131 scopus 로고    scopus 로고
    • Transfer of IgG in the female genital tract by MHC class I-related neonatal Fc receptor (FcRn) confers protective immunity to vaginal infection
    • Li, Z., et al. 2011. Transfer of IgG in the female genital tract by MHC class I-related neonatal Fc receptor (FcRn) confers protective immunity to vaginal infection. Proc. Natl. Acad. Sci. U. S. A. 108:4388-4393.
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 4388-4393
    • Li, Z.1
  • 27
    • 58149267963 scopus 로고    scopus 로고
    • Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys
    • Liu, J., et al. 2009. Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys. Nature 457:87-91.
    • (2009) Nature , vol.457 , pp. 87-91
    • Liu, J.1
  • 28
    • 47949112092 scopus 로고    scopus 로고
    • Activation of the JAK/STAT-1 signaling pathway by IFN-gamma can down-regulate functional expression of the MHC class I-related neonatal Fc receptor for IgG
    • Liu, X., et al. 2008. Activation of the JAK/STAT-1 signaling pathway by IFN-gamma can down-regulate functional expression of the MHC class I-related neonatal Fc receptor for IgG. J. Immunol. 181:449-463.
    • (2008) J. Immunol. , vol.181 , pp. 449-463
    • Liu, X.1
  • 29
    • 79955024081 scopus 로고    scopus 로고
    • The neonatal FcR-mediated presentation of immunecomplexed antigen is associated with endosomal and phagosomal pH and antigen stability in macrophages and dendritic cells
    • Liu, X., et al. 2011. The neonatal FcR-mediated presentation of immunecomplexed antigen is associated with endosomal and phagosomal pH and antigen stability in macrophages and dendritic cells. J. Immunol. 186:4674-4686.
    • (2011) J. Immunol. , vol.186 , pp. 4674-4686
    • Liu, X.1
  • 30
    • 79751482268 scopus 로고    scopus 로고
    • A mucosal gateway for vaccines
    • McGhee, J. R. 2011. A mucosal gateway for vaccines. Nat. Biotechnol. 29:136-138.
    • (2011) Nat. Biotechnol. , vol.29 , pp. 136-138
    • McGhee, J.R.1
  • 31
    • 77952423868 scopus 로고    scopus 로고
    • Antibody-mediated protection and the mucosal immune system of the genital tract: relevance to vaccine design
    • Mestecky, J., M. Raska, J. Novak, R. C. R. C. Alexander, and Z. Moldoveanu. 2010. Antibody-mediated protection and the mucosal immune system of the genital tract: relevance to vaccine design. J. Reprod. Immunol. 85:81-85.
    • (2010) J. Reprod. Immunol. , vol.85 , pp. 81-85
    • Mestecky, J.1    Raska, M.2    Novak, J.3    Alexander, R.C.R.C.4    Moldoveanu, Z.5
  • 32
    • 71849083999 scopus 로고    scopus 로고
    • Targeting the neonatal Fc receptor for antigen delivery using engineered fc fragments
    • Mi, W., et al. 2008. Targeting the neonatal Fc receptor for antigen delivery using engineered fc fragments. J. Immunol. 181:7550-7561.
    • (2008) J. Immunol. , vol.181 , pp. 7550-7561
    • Mi, W.1
  • 33
    • 77950469136 scopus 로고    scopus 로고
    • Targeted delivery of immunogen to primate m cells with tetragalloyl lysine dendrimer
    • Misumi, S., et al. 2009. Targeted delivery of immunogen to primate m cells with tetragalloyl lysine dendrimer. J. Immunol. 182:6061-6070.
    • (2009) J. Immunol. , vol.182 , pp. 6061-6070
    • Misumi, S.1
  • 34
    • 4644330206 scopus 로고    scopus 로고
    • Role of inducible bronchus associated lymphoid tissue (iBALT) in respiratory immunity
    • Moyron-Quiroz, J. E., et al. 2004. Role of inducible bronchus associated lymphoid tissue (iBALT) in respiratory immunity. Nat. Med. 10:927-934.
    • (2004) Nat. Med. , vol.10 , pp. 927-934
    • Moyron-Quiroz, J.E.1
  • 35
    • 0035174046 scopus 로고    scopus 로고
    • Collaboration of epithelial cells with organized mucosal lymphoid tissues
    • Neutra, M. R., N. J. Mantis, and J.-P. Kraehenbuhl. 2001. Collaboration of epithelial cells with organized mucosal lymphoid tissues. Nat. Immunol. 2:1004-1009.
    • (2001) Nat. Immunol. , vol.2 , pp. 1004-1009
    • Neutra, M.R.1    Mantis, N.J.2    Kraehenbuhl, J.-P.3
  • 36
    • 33644836224 scopus 로고    scopus 로고
    • Mucosal vaccines: the promise and the challenge
    • Neutra, M. R., and P. A. Kozlowski. 2006. Mucosal vaccines: the promise and the challenge. Nat. Rev. Immunol. 6:148-158.
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 148-158
    • Neutra, M.R.1    Kozlowski, P.A.2
  • 37
    • 36549087144 scopus 로고    scopus 로고
    • A novel M cell specific carbohydrate-targeted mucosal vaccine effectively induces antigen-specific immune responses
    • Nochi, T., et al. 2007. A novel M cell specific carbohydrate-targeted mucosal vaccine effectively induces antigen-specific immune responses. J. Exp. Med. 204:2789-2796.
    • (2007) J. Exp. Med. , vol.204 , pp. 2789-2796
    • Nochi, T.1
  • 38
    • 0029825440 scopus 로고    scopus 로고
    • Intranasal immunization induces long-term protection in mice against a Chlamydia trachomatis genital challenge
    • Pal, S., E. M. Peterson, and L. M. de la Maza. 1996. Intranasal immunization induces long-term protection in mice against a Chlamydia trachomatis genital challenge. Infect. Immun. 64:5341-5348.
    • (1996) Infect. Immun. , vol.64 , pp. 5341-5348
    • Pal, S.1    Peterson, E.M.2    de la Maza, L.M.3
  • 39
    • 0030863128 scopus 로고    scopus 로고
    • Immunoglobulin G is the main protective antibody in mouse vaginal secretions after vaginal immunization with attenuated herpes simplex virus type 2
    • Parr, E. L., and M. B. Parr. 1997. Immunoglobulin G is the main protective antibody in mouse vaginal secretions after vaginal immunization with attenuated herpes simplex virus type 2. J. Virol. 71:8109-9115.
    • (1997) J. Virol. , vol.71 , pp. 8109-9115
    • Parr, E.L.1    Parr, M.B.2
  • 40
    • 48249148222 scopus 로고    scopus 로고
    • Dependence of antibody-mediated presentation of antigen on FcRn
    • Qiao, S. W., et al. 2008. Dependence of antibody-mediated presentation of antigen on FcRn. Proc. Natl. Acad. Sci. U. S. A. 105:9337-9342.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 9337-9342
    • Qiao, S.W.1
  • 41
    • 45949101974 scopus 로고    scopus 로고
    • Utilization of Fc receptors as a mucosal vaccine strategy against an intracellular bacterium, Francisella tularensis
    • Rawool, D. B., et al. 2008. Utilization of Fc receptors as a mucosal vaccine strategy against an intracellular bacterium, Francisella tularensis. J. Immunol. 180:5548-5557.
    • (2008) J. Immunol. , vol.180 , pp. 5548-5557
    • Rawool, D.B.1
  • 42
    • 34548229364 scopus 로고    scopus 로고
    • FcRn: the neonatal Fc receptor comes of age
    • Roopenian, D. C., and S. Akilesh. 2007. FcRn: the neonatal Fc receptor comes of age. Nat. Rev. Immunol. 7:715-725.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 715-725
    • Roopenian, D.C.1    Akilesh, S.2
  • 43
    • 0037379288 scopus 로고    scopus 로고
    • The MHC class I-like IgG receptor controls perinatal IgG transport, IgG homeostasis, and fate of IgG-Fc-coupled drugs
    • Roopenian, D. C., et al. 2003. The MHC class I-like IgG receptor controls perinatal IgG transport, IgG homeostasis, and fate of IgG-Fc-coupled drugs. J. Immunol. 170:3528-3533.
    • (2003) J. Immunol. , vol.170 , pp. 3528-3533
    • Roopenian, D.C.1
  • 44
    • 0037025895 scopus 로고    scopus 로고
    • Receptor-mediated immunoglobulin G transport across mucosal barriers in adult life: functional expression of FcRn in the mammalian lung
    • Spiekermann, G. M., et al. 2002. Receptor-mediated immunoglobulin G transport across mucosal barriers in adult life: functional expression of FcRn in the mammalian lung. J. Exp. Med. 196:303-310.
    • (2002) J. Exp. Med. , vol.196 , pp. 303-310
    • Spiekermann, G.M.1
  • 45
    • 33746976718 scopus 로고    scopus 로고
    • Ligand valency affects transcytosis, recycling and intracellular trafficking mediated by the neonatal Fc receptor
    • Tesar, D. B., N. E. Tiangco, and P. J. Bjorkman. 2006. Ligand valency affects transcytosis, recycling and intracellular trafficking mediated by the neonatal Fc receptor. Traffic 7:1127-1142.
    • (2006) Traffic , vol.7 , pp. 1127-1142
    • Tesar, D.B.1    Tiangco, N.E.2    Bjorkman, P.J.3
  • 46
    • 33645048192 scopus 로고    scopus 로고
    • + T cell immunity in mice with anti-dendritic cell HIV Gag fusion antibody vaccine
    • + T cell immunity in mice with anti-dendritic cell HIV Gag fusion antibody vaccine. J. Exp. Med. 203:607-617.
    • (2006) J. Exp. Med. , vol.203 , pp. 607-617
    • Trumpfheller, C.1
  • 47
    • 30544448127 scopus 로고    scopus 로고
    • Triggering TLR signaling in vaccination
    • van Duin, D., R. Medzhitov, and A. C. Shaw. 2006. Triggering TLR signaling in vaccination. Trends Immunol. 27:49-55.
    • (2006) Trends Immunol , vol.27 , pp. 49-55
    • van Duin, D.1    Medzhitov, R.2    Shaw, A.C.3
  • 48
    • 69949115639 scopus 로고    scopus 로고
    • Chapter 4: multitasking by exploitation of intracellular transport functions the many faces of FcRn
    • Ward, E. S., and R. J. Ober. 2009. Chapter 4: multitasking by exploitation of intracellular transport functions the many faces of FcRn. Adv. Immunol. 103:77-115.
    • (2009) Adv. Immunol. , vol.103 , pp. 77-115
    • Ward, E.S.1    Ober, R.J.2
  • 49
    • 0030701953 scopus 로고    scopus 로고
    • Nasal lymphoid tissue (NALT) as a mucosal immune inductive site
    • Wu, H. Y., H. Nguyen, and M. W. Russell. 1997. Nasal lymphoid tissue (NALT) as a mucosal immune inductive site. Scand. J. Immunol. 46:506-513.
    • (1997) Scand. J. Immunol. , vol.46 , pp. 506-513
    • Wu, H.Y.1    Nguyen, H.2    Russell, M.W.3
  • 50
    • 79751497661 scopus 로고    scopus 로고
    • Efficient mucosal delivery of vaccine using the FcRn-mediated IgG transfer pathway
    • Ye, L., R. Zeng, Y. Bai, D. C. Roopenian, and X. Zhu. 2011. Efficient mucosal delivery of vaccine using the FcRn-mediated IgG transfer pathway. Nat. Biotechnol. 29:158-163.
    • (2011) Nat. Biotechnol. , vol.29 , pp. 158-163
    • Ye, L.1    Zeng, R.2    Bai, Y.3    Roopenian, D.C.4    Zhu, X.5
  • 51
    • 53149112371 scopus 로고    scopus 로고
    • The MHC class II-associated invariant chain interacts with the neonatal Fc gamma receptor and modulates its trafficking to endosomal/ lysosomal compartments
    • Ye, L., et al. 2008. The MHC class II-associated invariant chain interacts with the neonatal Fc gamma receptor and modulates its trafficking to endosomal/ lysosomal compartments. J. Immunol. 181:2572-2585.
    • (2008) J. Immunol. , vol.181 , pp. 2572-2585
    • Ye, L.1
  • 52
    • 2942516894 scopus 로고    scopus 로고
    • Human neonatal Fc receptor mediates transport of IgG into luminal secretions for delivery of antigens to mucosal dendritic cells
    • Yoshida, M., et al. 2004. Human neonatal Fc receptor mediates transport of IgG into luminal secretions for delivery of antigens to mucosal dendritic cells. Immunity 20:769-783.
    • (2004) Immunity , vol.20 , pp. 769-783
    • Yoshida, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.