A facile synthesis of carbocycle-fused mono and bis-1,2,3-selenadiazoles and their antimicrobial and antimycobacterial studies

European Journal of Medicinal Chemistry

Volumn 46, Issue 11, 2011, Pages 5465-5472

  Chitra, Selvam ^a   Paul, Nidhin ^b   Muthusubramanian, Shanmugam ^b   Manisankar, Paramasivam ^a   Yogeeswari, Perumal ^c   Sriram, Dharmarajan ^c  

^a ALAGAPPA UNIVERSITY   (India)

^b MADURAI KAMARAJ UNIVERSITY   (India)

^c BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

Author keywords

1,2,3 Selenadiazole; Antimicrobial activity; Mycobacterium tuberculosis; Oxidative cyclization

Indexed keywords

1 (2 NAPHTHYL) 3 PHENYL 3 (4,5,6,7 TETRAHYDRO 1,2,3 BENZOSELENADIAZOL 4 YL) 1 PROPANONE; 1 (4 CHLOROPHENYL) 3 PHENYL 3 (4,5,6,7 TETRAHYDRO 1,2,3 BENZOSELENADIAZOL 4 YL) 1 PROPANONE; 1 (4 METHOXYPHENYL) 3 PHENYL 3 (4,5,6,7 TETRAHYDRO 1,2,3 BENZOSELENADIAZOL 4 YL) 1 PROPANONE; 1 (4 METHYLPHENYL) 3 PHENYL 3 (4,5,6,7 TETRAHYDRO 1,2,3 BENZOSELENADIAZOL 4 YL) 1 PROPANONE; 1,3 DI (4 CHLOROPHENYL) 3 (4,5,6,7 TETRAHYDRO 1,2,3 BENZOSELENADIAZOL 4 YL) 1 PROPANONE; 1,3 DI(4 CHLOROPHENYL) 3 (4,5,6,7 TETRAHYDRO 1,2,3 BENZOSELENADIAZOL 4 YL) 1 PROPANONE; 1,3 DIPHENYL 3 (4,5,6,7 TETRAHYDRO 1,2,3 BENZOSELENADIAZOL 4 YL) 1 PROPANONE; 3 (4 CHLOROPHENYL) 1 (4 METHOXYPHENYL) 3 (4,5,6,7 TETRAHYDRO 1,2,3 BENZOSELENADIAZOL 4 YL) 1 PROPANONE; 3 (4 CHLOROPHENYL) 1 (4 METHYLPHENYL) 3 (4,5,6,7 TETRAHYDRO 1,2,3 BENZOSELENADIAZOL 4 YL) 1 PROPANONE; 3 (4 CHLOROPHENYL) 1 PHENYL 3 (4,5,6,7 TETRAHYDRO 1,2,3 BENZOSELENADIAZOL 4 YL) 1 PROPANONE; 3 (4 METHOXYPHENYL) 1 PHENYL 3 (4,5,6,7 TETRAHYDRO 1,2,3 BENZOSELENADIAZOL 4 YL) 1 PROPANONE; 3 (4 METHYLPHENYL) 1 PHENYL 3 (4,5,6,7 TETRAHYDRO 1,2,3 BENZOSELENADIAZOL 4 YL) 1 PROPANONE; 4 (4 CHLOROPHENYL)[4 (4 METHOXYPHENYL) 1,2,3 SELENADIAZOL 5YL]METHYL 4,5,6,7 TETRAHYDRO 1,2,3 BENZOSELENADIAZOLE; 4 (4 CHLOROPHENYL)[4 (4 METHYLPHENYL) 1,2,3 SELENADIAZOL 5 YL]METHYL 4,5,6,7 TETRAHYDRO 1,2,3 BENZOSELENADIAZOLE; 4 [(4 CHLOROPHENYL)(4 PHENYL 1,2,3 SELENADIAZOL 5 YL)METHYL]4,5,6,7 TETRAHYDRO 1,2,3 BENZOSELENADIAZOLE; 4 [(4 METHOXYPHENYL)(4 PHENYL 1,2,3 SELENADIAZOL 5 YL)METHYL] 4,5,6,7 TETRAHYDRO 1,2,3 BENZOSELENADIAZOLE; 4 [(4 METHYLPHENYL)(4 PHENYL 1,2,3 SELENADIAZOL 5 YL)METHYL] 4,5,6,7 TETRAHYDRO 1,2,3 BENZOSELENADIAZOLE; 4 [4 (4 CHLOROPHENYL) 1,2,3 SELENADIAZOL 5 YL](PHENYL)METHYL] 4,5,6,7 TETRAHYDRO 1,2,3 BENZOSELENADIAZOLE; 4 [[4 (2 NAPHTHYL) 1,2,3 SELENADIAZOL 5 YL](PHENYL)METHYL]4,5,6,7 TETRAHYDRO 1,2,3 BENZOSELENADIAZOLE; 4 [[4 (4 METHOXYPHENYL) 1,2,3 SELENADIAZOL 5 YL](PHENYL)METHYL] 4,5,6,7 TETRAHYDRO 1,2,3 BENZOSELENADIAZOLE; 4 [PHENYL(4 PHENYL 1,2,3 SELENADIAZOL 5 YL)METHYL] 4,5,6,7 TETRAHYDRO 1,2,3 BENZOSELENADIAZOLE; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; ANTIMYCOBACTERIAL AGENT; CIPROFLOXACIN; CLOTRIMAZOLE; ETHAMBUTOL; ISONIAZID; RIFAMPICIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; CANDIDA ALBICANS; CYCLIZATION; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ESCHERICHIA COLI; FERTILIZATION IN VITRO; HUMAN; HUMAN CELL; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; OXIDATION; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION;

ANTI-BACTERIAL AGENTS; AZOLES; CANDIDA ALBICANS; CHEMISTRY TECHNIQUES, SYNTHETIC; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS;

EID: 80054959315     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.09.007     Document Type: Article

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