A new method of synthesising (±)-thalictroidine and (±)-hygrine

Tetrahedron Letters

Volumn 52, Issue 13, 2011, Pages 1520-1522

  Ponpandian, T ^a   Muthusubramanian, S ^a  

^a MADURAI KAMARAJ UNIVERSITY   (India)

Author keywords

( ) Hygrine; ( ) Thalictroidine; Piperidine alkaloids; Pyrrolidine alkaloids; Tandem SN2 Micheal reaction; Wittig reagent

Indexed keywords

ALKALOID DERIVATIVE; HYGRINE; THALICTROIDINE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; DEMETHYLATION; DRUG STRUCTURE; DRUG SYNTHESIS; SUBSTITUTION REACTION;

EID: 79951944278     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2011.01.132     Document Type: Article

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24. 3) δ 3.87 (3H, s), 6.22 (2H, d), 6.98 (2H, d), 7.62-7.67 (m, 6H), 7.73-7.75 (m, 3H), 7.91-7.96 (m, 6H), 8.43 (2H, d).
25. 3) 26.6, 31.7, 32.1, 33.2, 55.4, 113.7, 125.9, 130.6, 130.7, 147.5, 163.3, 188.8; m/z 297.0.
26. 3) 23.6, 25.7, 32.2, 41.8, 43.5, 55.4, 56.3, 59.6, 113.7, 130.3, 130.4, 163.5, 197.8; m/z 248.1.
27. -1; m/z 234.1.
28. E. Vedejs, M.J. Arnost, and J. Hagen J. Org. Chem. 18 1979 3230
29. 3) 27.0, 30.6, 30.8, 32.4, 132.0, 145.6, 198.2.
30. -1 (Neat) 1713; m/z 142.1.