Design, synthesis, and biological studies of efficient multivalent melanotropin ligands: Tools toward melanoma diagnosis and treatment

Journal of Medicinal Chemistry

Volumn 54, Issue 20, 2011, Pages 7375-7384

  Brabez, Nabila ^a,b,c,d   Lynch, Ronald M ^e   Xu, Liping ^f   Gillies, Robert J ^f   Chassaing, Gerard ^a,b,c   Lavielle, Solange ^a,b,c   Hruby, Victor J ^d  

^a Centre National de la Recherche Scientifique   (France)

^b CNRS   (France)

^c ECOLE NORMALE SUPÉRIEURE   (France)

^d The University of Arizona   (United States)

^e UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^f H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLIC AMP; LIGAND; MELANOCORTIN 4 RECEPTOR; MELANOTROPIN LIGAND DERIVATIVE; POLYMER; UNCLASSIFIED DRUG;

ARTICLE; CANCER DIAGNOSIS; CANCER THERAPY; DRUG DESIGN; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MELANOMA; PEPTIDE SYNTHESIS; PROTEIN EXPRESSION;

BINDING, COMPETITIVE; CYCLIC AMP; DENDRIMERS; DRUG DESIGN; HEK293 CELLS; HUMANS; LIGANDS; MELANOCYTE-STIMULATING HORMONES; MELANOMA; PEPTIDES; RECEPTOR, MELANOCORTIN, TYPE 4; SKIN NEOPLASMS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 80054935311     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm2009937     Document Type: Article

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