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Volumn 45, Issue 2, 2011, Pages 236-245

17β-estradiol protects dopaminergic neurons in organotypic slice of mesencephalon by MAPK-mediated activation of anti-apoptosis gene BCL2

Author keywords

6 OHDA; Neuroprotection; Signaling molecules

Indexed keywords

ESTRADIOL; GLIAL FIBRILLARY ACIDIC PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; TOLL LIKE RECEPTOR 4;

EID: 80054897981     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-011-9500-z     Document Type: Article
Times cited : (35)

References (31)
  • 1
    • 33750459730 scopus 로고    scopus 로고
    • Parkinsonism genes: Culprits and clues
    • DOI 10.1111/j.1471-4159.2006.04102.x
    • A Abeliovich M Flint Beal 2006 Parkinsonism genes: culprits and clues J Neurochem 99 1062 1072 16836655 10.1111/j.1471-4159.2006.04102.x 1:CAS:528:DC%2BD28Xht1yks7vM (Pubitemid 44655273)
    • (2006) Journal of Neurochemistry , vol.99 , Issue.4 , pp. 1062-1072
    • Abeliovich, A.1    Flint Beal, M.2
  • 2
    • 33947692720 scopus 로고    scopus 로고
    • +-induced dopamine neuron death is mediated by ERα in primary cultures of mouse mesencephalon
    • DOI 10.1016/j.expneurol.2007.01.020, PII S0014488607000295
    • M Bains JC Cousins JL Roberts 2007 Neuroprotection by estrogen against MPP+-induced dopamine neuron death is mediated by ERalpha in primary cultures of mouse mesencephalon Exp Neurol 204 767 776 17320868 10.1016/j.expneurol.2007. 01.020 1:CAS:528:DC%2BD2sXjslSku7w%3D (Pubitemid 46497065)
    • (2007) Experimental Neurology , vol.204 , Issue.2 , pp. 767-776
    • Bains, M.1    Cousins, J.C.2    Roberts, J.L.3
  • 3
    • 9244239174 scopus 로고    scopus 로고
    • Estrogen modulates microglial inflammatory mediator production via interactions with estrogen receptor β
    • DOI 10.1210/en.2004-0619
    • AE Baker VM Brautigam JJ Watters 2004 Estrogen modulates microglial inflammatory mediator production via interactions with estrogen receptor beta Endocrinology 145 5021 5032 15256495 10.1210/en.2004-0619 1:CAS:528: DC%2BD2cXptVyhtbk%3D (Pubitemid 39551121)
    • (2004) Endocrinology , vol.145 , Issue.11 , pp. 5021-5032
    • Baker, A.E.1    Brautigam, V.M.2    Watters, J.J.3
  • 4
    • 0037345781 scopus 로고    scopus 로고
    • Estrogen activates protein kinase C in neurons: Role in neuroprotection
    • DOI 10.1046/j.1471-4159.2003.01631.x
    • M Cordey U Gundimeda R Gopalakrishna CJ Pike 2003 Estrogen activates protein kinase C in neurons: role in neuroprotection J Neurochem 84 1340 1348 12614334 10.1046/j.1471-4159.2003.01631.x 1:CAS:528:DC%2BD3sXisVaqu7c%3D (Pubitemid 36343600)
    • (2003) Journal of Neurochemistry , vol.84 , Issue.6 , pp. 1340-1348
    • Cordey, M.1    Gundimeda, U.2    Gopalakrishna, R.3    Pike, C.J.4
  • 5
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to the cell- intrinsic death machinery
    • DOI 10.1016/S0092-8674(00)80405-5
    • SR Datta H Dudek X Tao S Masters H Fu Y Gotoh, et al. 1997 Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery Cell 91 231 241 9346240 10.1016/S0092-8674(00)80405-5 1:CAS:528:DyaK2sXntVyiu7k%3D (Pubitemid 27456390)
    • (1997) Cell , vol.91 , Issue.2 , pp. 231-241
    • Datta, S.R.1    Dudek, H.2    Xu, T.3    Masters, S.4    Haian, F.5    Gotoh, Y.6    Greenberg, M.E.7
  • 6
    • 12344317241 scopus 로고    scopus 로고
    • Quantification of viability in organotypic multicellular spheroids of human malignant glioma using lactate dehydrogenase activity: A rapid and reliable automated assay
    • DOI 10.1369/jhc.4A6301.2005
    • PC De Witt Hamer A Jonker S Leenstra JM Ruijter CJ Van Noorden 2005 Quantification of viability in organotypic multicellular spheroids of human malignant glioma using lactate dehydrogenase activity: a rapid and reliable automated assay J Histochem Cytochem 53 23 34 15637335 (Pubitemid 40130117)
    • (2005) Journal of Histochemistry and Cytochemistry , vol.53 , Issue.1 , pp. 23-34
    • De Witt Hamer, P.C.1    Jonker, A.2    Leenstra, S.3    Ruijter, J.M.4    Van Noorden, C.J.F.5
  • 7
    • 0038620461 scopus 로고    scopus 로고
    • Estrogen as neuroprotectant of nigrostriatal dopaminergic system: Laboratory and clinical studies
    • DOI 10.1385/ENDO:21:1:67
    • D Dluzen M Horstink 2003 Estrogen as neuroprotectant of nigrostriatal dopaminergic system: laboratory and clinical studies Endocr 21 67 75 10.1385/ENDO:21:1:67 1:CAS:528:DC%2BD3sXkvFSiu70%3D (Pubitemid 36677345)
    • (2003) Endocrine , vol.21 , Issue.1 , pp. 67-75
    • Dluzen, D.E.1    Horstink, M.W.I.M.2
  • 8
    • 10444239345 scopus 로고    scopus 로고
    • Developmental and genetic influences upon gender differences in methamphetamine-induced nigrostriatal dopaminergic neurotoxicity
    • DOI 10.1196/annals.1316.026
    • DE Dluzen JL McDermott 2004 Developmental and genetic influences upon gender differences in methamphetamine-induced nigrostriatal dopaminergic neurotoxicity Ann NY Acad Sci 1025 205 220 15542719 10.1196/annals.1316.026 1:CAS:528:DC%2BD2MXkvF2qsA%3D%3D (Pubitemid 39643864)
    • (2004) Annals of the New York Academy of Sciences , vol.1025 , pp. 205-220
    • Dluzen, D.E.1    McDermott, J.L.2
  • 9
    • 17844407395 scopus 로고    scopus 로고
    • Glia-neuron crosstalk in the neuroprotective mechanisms of sex steroid hormones
    • DOI 10.1016/j.brainresrev.2004.12.018, Glial-Neuron Crosstalk in Neuroinflamation, Neurodegeneration and Neuroprotection
    • D Garcia-Ovejero I Azcoitia LL Doncarlos RC Melcangi LM Garcia-Segura 2005 Glia-neuron crosstalk in the neuroprotective mechanisms of sex steroid hormones Brain Res Brain Res Rev 48 273 286 15850667 10.1016/j.brainresrev.2004. 12.018 1:CAS:528:DC%2BD2MXjs1Cmu70%3D (Pubitemid 40585759)
    • (2005) Brain Research Reviews , vol.48 , Issue.2 , pp. 273-286
    • Garcia-Ovejero, D.1    Azcoitia, I.2    DonCarlos, L.L.3    Melcangi, R.C.4    Garcia-Segura, L.M.5
  • 11
    • 64749107405 scopus 로고    scopus 로고
    • 17beta-Estradiol-induced enhancement of estrogen receptor biosynthesis via MAPK pathway in mouse skeletal muscle myoblasts
    • 19340542 10.1007/s12576-009-0023-0 1:CAS:528:DC%2BD1MXlvFCmtbs%3D
    • J Hatae N Takami H Lin A Honda R Inoue 2009 17beta-Estradiol-induced enhancement of estrogen receptor biosynthesis via MAPK pathway in mouse skeletal muscle myoblasts J Physiol Sci 59 181 190 19340542 10.1007/s12576-009-0023-0 1:CAS:528:DC%2BD1MXlvFCmtbs%3D
    • (2009) J Physiol Sci , vol.59 , pp. 181-190
    • Hatae, J.1    Takami, N.2    Lin, H.3    Honda, A.4    Inoue, R.5
  • 12
    • 0034193219 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase mediates neuroprotection by estrogen in cultured cortical neurons
    • DOI 10.1002/(SICI)1097-4547(20000501)60:3<321::AID-JNR6>3.0.CO;2-T
    • K Honda H Sawada T Kihara M Urushitani T Nakamizo A Akaike, et al. 2000 Phosphatidylinositol 3-kinase mediates neuroprotection by estrogen in cultured cortical neurons J Neurosci Res 60 321 327 10797534 10.1002/(SICI)1097- 4547(20000501)60:3<321::AID-JNR6>3.0.CO;2-T 1:CAS:528:DC%2BD3cXivFyltLg%3D (Pubitemid 30253595)
    • (2000) Journal of Neuroscience Research , vol.60 , Issue.3 , pp. 321-327
    • Honda, K.1    Sawada, H.2    Kihara, T.3    Urushitani, M.4    Nakamizo, T.5    Akaike, A.6    Shimohama, S.7
  • 13
    • 34249791777 scopus 로고    scopus 로고
    • Dopaminergic neurons intrinsic to the striatum
    • DOI 10.1111/j.1471-4159.2006.04430.x
    • P Huot A Parent 2007 Dopaminergic neurons intrinsic to the striatum J Neurochem 101 1441 1447 17286588 10.1111/j.1471-4159.2006.04430.x 1:CAS:528:DC%2BD2sXnvVantr0%3D (Pubitemid 46848839)
    • (2007) Journal of Neurochemistry , vol.101 , Issue.6 , pp. 1441-1447
    • Huot, P.1    Parent, A.2
  • 14
    • 33847062554 scopus 로고    scopus 로고
    • MAPK signaling is critical to estradiol protection of CA1 neurons in global ischemia
    • 17138646 10.1210/en.2006-1137 1:CAS:528:DC%2BD2sXitlWns7Y%3D
    • T Jover-Mengual RS Zukin AM Etgen 2007 MAPK signaling is critical to estradiol protection of CA1 neurons in global ischemia Endocrinology 148 1131 1143 17138646 10.1210/en.2006-1137 1:CAS:528:DC%2BD2sXitlWns7Y%3D
    • (2007) Endocrinology , vol.148 , pp. 1131-1143
    • Jover-Mengual, T.1    Zukin, R.S.2    Etgen, A.M.3
  • 15
    • 0034032022 scopus 로고    scopus 로고
    • Estrogen receptor interaction with co-activators and co-repressors
    • DOI 10.1016/S0039-128X(99)00107-5, PII S0039128X99001075
    • CM Klinge 2000 Estrogen receptor interaction with co-activators and co-repressors Steroids 65 227 251 10751636 10.1016/S0039-128X(99)00107-5 1:CAS:528:DC%2BD3cXit1Wntbc%3D (Pubitemid 30177344)
    • (2000) Steroids , vol.65 , Issue.5 , pp. 227-251
    • Klinge, C.M.1
  • 16
    • 11144224509 scopus 로고    scopus 로고
    • The 17α and 17β isomers of estradiol both induce rapid spine synapse formation in the Ca1 hippocampal subfield of ovariectomized female rats
    • DOI 10.1210/en.2004-0730
    • NJ MacLusky VN Luine T Hajszan C Leranth 2005 The 17alpha and 17beta isomers of estradiol both induce rapid spine synapse formation in the CA1 hippocampal subfield of ovariectomized female rats Endocrinology 146 287 293 15486220 10.1210/en.2004-0730 1:CAS:528:DC%2BD2cXhtFGmt7bE (Pubitemid 40051751)
    • (2005) Endocrinology , vol.146 , Issue.1 , pp. 287-293
    • MacLusky, N.J.1    Luine, V.N.2    Hajszan, T.3    Leranth, C.4
  • 17
    • 0037381830 scopus 로고    scopus 로고
    • Tetrahydrobiopterin precursor sepiapterin provides protection against neurotoxicity of 1-methyl-4-phenylpyridinium in nigral slice cultures
    • JT Madsen P Jansen C Hesslinger M Meyer J Zimmer JB Gramsbergen 2003 Tetrahydrobiopterin precursor sepiapterin provides protection against neurotoxicity of 1-methyl-4-phenylpyridinium in nigral slice cultures J Neurochem 85 214 223 12641743 10.1046/j.1471-4159.2003.01666.x 1:CAS:528:DC%2BD3sXislOlurk%3D (Pubitemid 36389711)
    • (2003) Journal of Neurochemistry , vol.85 , Issue.1 , pp. 214-223
    • Madsen, J.T.1    Jansen, P.2    Hesslinger, C.3    Meyer, M.4    Zimmer, J.5    Gramsbergen, J.B.6
  • 18
    • 0142247461 scopus 로고    scopus 로고
    • Estradiol prevents amyloid-β peptide-induced cell death in a cholinergic cell line via modulation of a classical estrogen receptor
    • DOI 10.1016/S0306-4522(03)00464-0
    • R Marin B Guerra JG Hernandez-Jimenez XL Kang JD Fraser FJ Lopez, et al. 2003 Estradiol prevents amyloid-beta peptide-induced cell death in a cholinergic cell line via modulation of a classical estrogen receptor Neuroscience 121 917 926 14580942 10.1016/S0306-4522(03)00464-0 1:CAS:528:DC%2BD3sXot1yqsr0%3D (Pubitemid 37324591)
    • (2003) Neuroscience , vol.121 , Issue.4 , pp. 917-926
    • Marin, R.1    Guerra, B.2    Hernandez-Jimenez, J.-G.3    Kang, X.-L.4    Fraser, J.D.5    Lopez, F.J.6    Alonso, R.7
  • 19
    • 44949116236 scopus 로고    scopus 로고
    • Invited article: Changing concepts in Parkinson disease: Moving beyond the decade of the brain
    • 18490620 10.1212/01.wnl.0000312515.52545.51
    • C Marras A Lang 2008 Invited article: changing concepts in Parkinson disease: moving beyond the decade of the brain Neurology 70 1996 2003 18490620 10.1212/01.wnl.0000312515.52545.51
    • (2008) Neurology , vol.70 , pp. 1996-2003
    • Marras, C.1    Lang, A.2
  • 20
    • 53749104246 scopus 로고    scopus 로고
    • Membrane estrogen receptors acting through metabotropic glutamate receptors: An emerging mechanism of estrogen action in brain
    • 18670908 10.1007/s12035-008-8034-z 1:CAS:528:DC%2BD1cXhtVSgtLrK
    • PE Micevych PG Mermelstein 2008 Membrane estrogen receptors acting through metabotropic glutamate receptors: an emerging mechanism of estrogen action in brain Mol Neurobiol 38 66 77 18670908 10.1007/s12035-008-8034-z 1:CAS:528:DC%2BD1cXhtVSgtLrK
    • (2008) Mol Neurobiol , vol.38 , pp. 66-77
    • Micevych, P.E.1    Mermelstein, P.G.2
  • 21
    • 33644526277 scopus 로고    scopus 로고
    • Estrogen, neuroinflammation and neuroprotection in Parkinson's disease: Glia dictates resistance versus vulnerability to neurodegeneration
    • 16337092 10.1016/j.neuroscience.2005.07.060 1:CAS:528: DC%2BD28XitVGjtL4%3D
    • MC Morale PA Serra F L'Episcopo C Tirolo S Caniglia N Testa, et al. 2006 Estrogen, neuroinflammation and neuroprotection in Parkinson's disease: glia dictates resistance versus vulnerability to neurodegeneration Neuroscience 138 869 878 16337092 10.1016/j.neuroscience.2005.07.060 1:CAS:528: DC%2BD28XitVGjtL4%3D
    • (2006) Neuroscience , vol.138 , pp. 869-878
    • Morale, M.C.1    Serra, P.A.2    L'Episcopo, F.3    Tirolo, C.4    Caniglia, S.5    Testa, N.6
  • 22
    • 0037440049 scopus 로고    scopus 로고
    • Effects of creatine supplementation on housekeeping genes in human skeletal muscle using real-time RT-PCR
    • RM Murphy KK Watt D Cameron-Smith CJ Gibbons RJ Snow 2003 Effects of creatine supplementation on housekeeping genes in human skeletal muscle using real-time RT-PCR Physiol Genomics 12 163 174 12419855 1:CAS:528: DC%2BD3sXhtl2rurw%3D (Pubitemid 37139696)
    • (2003) Physiological Genomics , vol.12 , pp. 163-174
    • Murphy, R.M.1    Watt, K.K.O.2    Cameron-Smith, D.3    Gibbons, C.J.4    Snow, R.J.5
  • 23
    • 34247588730 scopus 로고    scopus 로고
    • Estrogen and progestogen use in peri- and postmenopausal women: March 2007 position statement of the North American Menopause Society
    • DOI 10.1097/gme.0b013e31803167ab
    • North American Menopause Society 2007 Estrogen and progestogen use in peri- and postmenopausal women: March 2007 position statement of The North American Menopause Society Menopause 14 168 182 10.1097/gme.0b013e31803167ab (Pubitemid 46673467)
    • (2007) Menopause , vol.14 , Issue.2 , pp. 168-182
  • 24
    • 33847770799 scopus 로고    scopus 로고
    • Estrogen action in neuroprotection and brain inflammation
    • DOI 10.1196/annals.1386.035, Estrogens and Human Diseases
    • S Pozzi V Benedusi A Maggi E Vegeto 2006 Estrogen action in neuroprotection and brain inflammation Ann NY Acad Sci 1089 302 323 17261778 10.1196/annals.1386.035 1:CAS:528:DC%2BD2sXhsFerur4%3D (Pubitemid 47092090)
    • (2006) Annals of the New York Academy of Sciences , vol.1089 , pp. 302-323
    • Pozzi, S.1    Benedusi, V.2    Maggi, A.3    Vegeto, E.4
  • 25
    • 0348109349 scopus 로고    scopus 로고
    • Estradiol Attenuates Programmed Cell Death after Stroke-Like Injury
    • SW Rau DB Dubal M Bottner LM Gerhold PM Wise 2003 Estradiol attenuates programmed cell death after stroke-like injury J Neurosci 23 11420 11426 14673006 1:CAS:528:DC%2BD3sXhtVWgtrrP (Pubitemid 37549698)
    • (2003) Journal of Neuroscience , vol.23 , Issue.36 , pp. 11420-11426
    • Rau, S.W.1    Dubal, D.B.2    Bottner, M.3    Gerhold, L.M.4    Wise, P.M.5
  • 27
    • 13144257746 scopus 로고    scopus 로고
    • Similarities between actions of estrogen and BDNF in the hippocampus: Coincidence or clue?
    • DOI 10.1016/j.tins.2004.12.005, PII S0166223604003728
    • HE Scharfman NJ Maclusky 2005 Similarities between actions of estrogen and BDNF in the hippocampus: coincidence or clue? Trends Neurosci 28 79 85 15667930 10.1016/j.tins.2004.12.005 1:CAS:528:DC%2BD2MXmslKmsA%3D%3D (Pubitemid 40178924)
    • (2005) Trends in Neurosciences , vol.28 , Issue.2 , pp. 79-85
    • Scharfman, H.E.1    MacLusky, N.J.2
  • 28
    • 34250378592 scopus 로고    scopus 로고
    • Gender differences in Parkinson's disease
    • DOI 10.1016/S1550-8579(07)80003-9, PII S1550857907800039
    • LM Shulman 2007 Gender differences in Parkinson's disease Gend Med 4 8 18 17584622 10.1016/S1550-8579(07)80003-9 (Pubitemid 46917063)
    • (2007) Gender Medicine , vol.4 , Issue.1 , pp. 8-18
    • Shulman, L.M.1
  • 29
    • 0025805120 scopus 로고
    • A simple method for organotypic cultures of nervous tissue
    • 1715499 10.1016/0165-0270(91)90128-M 1:STN:280:DyaK3MzltVymtA%3D%3D
    • L Stoppini PA Buchs D Muller 1991 A simple method for organotypic cultures of nervous tissue J Neurosci Methods 37 173 182 1715499 10.1016/0165-0270(91)90128-M 1:STN:280:DyaK3MzltVymtA%3D%3D
    • (1991) J Neurosci Methods , vol.37 , pp. 173-182
    • Stoppini, L.1    Buchs, P.A.2    Muller, D.3
  • 30
    • 0035663680 scopus 로고    scopus 로고
    • Estradiol is a protective factor in the adult and aging brain: Understanding of mechanisms derived from in vivo and in vitro studies
    • DOI 10.1016/S0165-0173(01)00136-9, PII S0165017301001369
    • PM Wise DB Dubal ME Wilson SW Rau M Bottner KL Rosewell 2001 Estradiol is a protective factor in the adult and aging brain: understanding of mechanisms derived from in vivo and in vitro studies Brain Res Brain Res Rev 37 313 319 11744096 10.1016/S0165-0173(01)00136-9 1:CAS:528:DC%2BD3MXovF2jurw%3D (Pubitemid 34020741)
    • (2001) Brain Research Reviews , vol.37 , Issue.1-3 , pp. 313-319
    • Wise, P.M.1    Dubal, D.B.2    Wilson, M.E.3    Rau, S.W.4    Bottner, M.5    Rosewell, K.L.6
  • 31
    • 24044441632 scopus 로고    scopus 로고
    • 2+ influx via L-type calcium channels activates the Src/ERK/cyclic-AMP response element binding protein signal pathway and BCL-2 expression in rat hippocampal neurons: A potential initiation mechanism for estrogen-induced neuroprotection
    • DOI 10.1016/j.neuroscience.2004.12.027, PII S0306452205000333
    • TW Wu JM Wang S Chen RD Brinton 2005 17beta-Estradiol induced Ca2+ influx via L-type calcium channels activates the Src/ERK/cyclic-AMP response element binding protein signal pathway and BCL-2 expression in rat hippocampal neurons: a potential initiation mechanism for estrogen-induced neuroprotection Neuroscience 135 59 72 16084662 10.1016/j.neuroscience.2004.12.027 1:CAS:528:DC%2BD2MXpslCntL8%3D (Pubitemid 41219738)
    • (2005) Neuroscience , vol.135 , Issue.1 , pp. 59-72
    • Wu, T.-W.1    Wang, J.M.2    Chen, S.3    Brinton, R.D.4


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