Two-generation reproductive and developmental toxicity assessment of dietary N-acetyl-L-aspartic acid in rats

Food and Chemical Toxicology

Volumn 49, Issue 12, 2011, Pages 3192-3205

  Karaman, Sule ^a   Barnett, John ^b   Sykes, Greg P ^c   Hong, Bonnie ^a   Delaney, Bryan ^a  

^a PIONEER HI BRED INTERNATIONAL INC   (United States)

^b CHARLES RIVER LABORATORIES   (United States)

^c DUPONT COMPANY   (United States)

Author keywords

Dietary administration; Food; L aspartate; N acetyl l aspartic acid; Reproductive toxicity

Indexed keywords

ASPARTIC ACID; N ACETYLASPARTIC ACID;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; BODY WEIGHT; BRAIN LEVEL; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; ESTRUS CYCLE; EYE EXAMINATION; FEMALE; FOOD INTAKE; HISTOPATHOLOGY; MALE; NEUROLOGIC EXAMINATION; NEUROTOXICITY; NONHUMAN; RAT; REPRODUCTIVE TOXICITY; RISK ASSESSMENT; SEXUAL BEHAVIOR; SEXUAL MATURATION; TOXICITY TESTING;

ANIMALS; ASPARTIC ACID; BODY WEIGHT; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; MALE; NEUROTOXICITY SYNDROMES; NO-OBSERVED-ADVERSE-EFFECT LEVEL; ORGAN SIZE; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCTION; TOXICITY TESTS;

MAMMALIA; RATTUS;

EID: 80054873256     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2011.08.025     Document Type: Article

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