Evaluation of the potential toxicity of dibromoacetonitrile-induced apoptosis and tumor-initiating activity in rat liver

Food and Chemical Toxicology

Volumn 49, Issue 12, 2011, Pages 3055-3062

  Assaf, Naglaa ^a   Salem, Neveen A ^b   Khalil, Wagdy K B ^b   Ahmed, Hanaa H ^b  

^a Misr University for Science and Technology   (Egypt)

^b NATIONAL RESEARCH CENTRE   (Egypt)

Author keywords

Apoptosis; Dibromoacetonitrile; Hepatotoxicity; Oxidative stress; Tumor initiating genes

Indexed keywords

ACETONITRILE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; DIBROMOACETONITRILE; MALONALDEHYDE; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; DNA FRAGMENTATION; GENE EXPRESSION PROFILING; IN VITRO STUDY; IN VIVO STUDY; LD 50; LIVER CELL; LIVER TOXICITY; MALE; MULTINUCLEAR CELL; NONHUMAN; ONCOGENE C MYC; OXIDATIVE STRESS; PROTEIN DEPLETION; PROTEIN FOLDING; RAT; UPREGULATION;

ACETONITRILES; ALANINE TRANSAMINASE; ANIMALS; ANTIOXIDANTS; APOPTOSIS; ASPARTATE AMINOTRANSFERASES; CARCINOGENS; DNA DAMAGE; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ERYTHROCYTES; LIVER; MALE; MALONDIALDEHYDE; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS;

EID: 80054858333     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2011.09.030     Document Type: Article

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