Metabolism and disposition of [14C]dibromoacetonitrile in rats and mice following oral and intravenous administration

Xenobiotica

Volumn 40, Issue 7, 2010, Pages 499-509

  Mathews, J M ^a   Pulliam Jr , D ^a   Black, S R ^a   Burka, L T ^b  

^a RTI INTERNATIONAL   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Alkylation; Dibromoacetonitrile; Disinfection by products; Metabolism

Indexed keywords

ACETONITRILE DERIVATIVE; CARBON DIOXIDE; DIBROMOACETONITRILE C 14; GLUTATHIONE; THIOGLYCOLIC ACID; UNCLASSIFIED DRUG; CARBON; DIBROMOACETONITRILE; THIOL DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISINFECTION; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; METABOLISM; MOUSE; NONHUMAN; RADIOACTIVITY; RAT; TISSUE DISTRIBUTION; URINARY EXCRETION; ANIMAL; CHEMISTRY; DOSE RESPONSE; INTRAVENOUS DRUG ADMINISTRATION; ORAL DRUG ADMINISTRATION; SPECIES DIFFERENCE; URINE;

MUS; RATTUS;

ACETONITRILES; ADMINISTRATION, ORAL; ANIMALS; CARBON RADIOISOTOPES; CHROMATOGRAPHY, LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTATHIONE; INJECTIONS, INTRAVENOUS; MALE; MASS SPECTROMETRY; MICE; RATS; SPECIES SPECIFICITY; SULFHYDRYL COMPOUNDS; TISSUE DISTRIBUTION;

EID: 77953553508     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.3109/00498251003802298     Document Type: Article

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