Quantification of myocardial blood flow using model based analysis of first-pass perfusion MRI: Extraction fraction of Gd-DTPA varies with myocardial blood flow in human myocardium

Magnetic Resonance in Medicine

Volumn 66, Issue 5, 2011, Pages 1391-1399

  Ishida, Masaki ^a   Ichihara, Takashi ^a,b   Nagata, Motonori ^a   Ishida, Nanaka ^a   Takase, Shinichi ^a   Kurita, Tairo ^a   Ito, Masaaki ^a   Takeda, Kan ^a   Sakuma, Hajime ^a  

^a MIE UNIVERSITY HOSPITAL   (Japan)

^b FUJITA HEALTH UNIVERSITY   (Japan)

Author keywords

extraction fraction; gadolinium contrast medium; myocardial blood flow; myocardial perfusion MRI

Indexed keywords

ADENOSINETRIPHOSPHATE; CONTRAST MEDIA; EXTRACTION; HEMODYNAMICS;

ABSOLUTE QUANTIFICATION; CONTRAST MEDIUM; EXTRACTION FRACTIONS; GADOLINIUM CONTRAST AGENTS; MODEL-BASED ANALYSIS; MYOCARDIAL BLOOD FLOW; MYOCARDIAL INFARCTION; MYOCARDIAL PERFUSION MRI;

BLOOD;

GADOLINIUM PENTETATE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; FEMALE; HEART LEFT VENTRICLE MASS; HEART MUSCLE BLOOD FLOW; HEMODYNAMICS; HUMAN; MALE; MYOCARDIAL PERFUSION IMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PERFUSION WEIGHTED IMAGING;

EID: 80054821001     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.22936     Document Type: Article

References (47)

1. Ishida N, Sakuma H, Motoyasu M, Okinaka T, Isaka N, Nakano T, Takeda K,. Noninfarcted myocardium: correlation between dynamic first-pass contrast-enhanced myocardial MR imaging and quantitative coronary angiography. Radiology 2003; 229: 209-216.
2. Ishida M, Sakuma H, Kato N, Ishida N, Kitagawa K, Shimono T, Yada I, Takeda K,. Contrast-enhanced MR imaging for evaluation of coronary artery disease before elective repair of aortic aneurysm. Radiology 2005; 237: 458-464.
3. Nagel E, Klein C, Paetsch I, Hettwer S, Schnackenburg B, Wegscheider K, Fleck E,. Magnetic resonance perfusion measurements for the noninvasive detection of coronary artery disease. Circulation 2003; 108: 432-437.
4. Jerosch-Herold M, Wilke N, Stillman AE,. Magnetic resonance quantification of the myocardial perfusion reserve with a Fermi function model for constrained deconvolution. Med Phys 1998; 25: 73-84.
5. Jerosch-Herold M, Swingen C, Seethamraju RT,. Myocardial blood flow quantification with MRI by model-independent deconvolution. Med Phys 2002; 29: 886-897.
6. Wilke N, Jerosch-Herold M, Wang Y, Huang Y, Christensen BV, Stillman AE, Ugurbil K, McDonald K, Wilson RF,. Myocardial perfusion reserve: assessment with multisection, quantitative, first-pass MR imaging. Radiology 1997; 204: 373-384.
7. Kety SS,. The theory and applications of the exchange of inert gas at the lungs and tissues. Pharmacol Rev 1951; 3: 1-41.
8. Diesbourg LD, Prato FS, Wisenberg G, Drost DJ, Marshall TP, Carroll SE, O'Neill B,. Quantification of myocardial blood flow and extracellular volumes using a bolus injection of Gd-DTPA: kinetic modeling in canine ischemic disease. Magn Reson Med 1992; 23: 239-253.
9. Larsson HB, Stubgaard M, Sondergaard L, Henriksen O,. In vivo quantification of the unidirectional influx constant for Gd-DTPA diffusion across the myocardial capillaries with MR imaging. J Magn Reson Imaging 1994; 4: 433-440.
10. Larsson HB, Fritz-Hansen T, Rostrup E, Sondergaard L, Ring P, Henriksen O,. Myocardial perfusion modeling using MRI. Magn Reson Med 1996; 35: 716-726.
11. Vallée JP, Lazeyras F, Kasuboski L, Chatelain P, Howarth N, Righetti A, Didier D,. Quantification of myocardial perfusion with FAST sequence and Gd bolus in patients with normal cardiac function. J Magn Reson Imaging 1999; 9: 197-203.
12. Vallée JP, Sostman HD, MacFall JR, DeGrado TR, Zhang J, Sebbag L, Cobb FR, Wheeler T, Hedlund LW, Turkington TG, Spritzer CE, Coleman RE,. Quantification of myocardial perfusion by MRI after coronary occlusion. Magn Reson Med 1998; 40: 287-297.
13. Renkin EM,. Transport of potassium-42 from blood to tissue in isolated mammalian skeletal muscles. Am J Physiol 1959; 197: 1205-1210.
14. Crone C,. The permeability of capillaries in various organs as determined by use of the "Indicator Diffusion" Method. Acta Physiol Scand 1963; 58: 292-305.
15. Rutland MD,. A single injection technique for subtraction of blood background in 131I-hippuran renograms. Br J Radiol 1979; 52: 134-137.
16. Patlak CS, Blasberg RG, Fenstermacher JD,. Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. J Cereb Blood Flow Metab 1983; 3: 1-7.
17. Ichihara T, Ishida M, Kitagawa K, Ichikawa Y, Natsume T, Yamaki N, Maeda H, Takeda K, Sakuma H,. Quantitative analysis of first-pass contrast-enhanced myocardial perfusion MRI using a Patlak plot method and blood saturation correction. Magn Reson Med 2009; 62: 373-383.
18. Tong CY, Prato FS, Wisenberg G, Lee TY, Carroll E, Sandler D, Wills J,. Techniques for the measurement of the local myocardial extraction efficiency for inert diffusible contrast agents such as gadopentate dimeglumine. Magn Reson Med 1993; 30: 332-336.
19. Tong CY, Prato FS, Wisenberg G, Lee TY, Carroll E, Sandler D, Wills J, Drost D,. Measurement of the extraction efficiency and distribution volume for Gd-DTPA in normal and diseased canine myocardium. Magn Reson Med 1993; 30: 337-346.
20. Pruessmann KP, Weiger M, Scheidegger MB, Boesiger P,. SENSE: sensitivity encoding for fast MRI. Magn Reson Med 1999; 42: 952-962.
21. Kurita T, Sakuma H, Onishi K, Ishida M, Kitagawa K, Yamanaka T, Tanigawa T, Kitamura T, Takeda K, Ito M,. Regional myocardial perfusion reserve determined using myocardial perfusion magnetic resonance imaging showed a direct correlation with coronary flow velocity reserve by Doppler flow wire. Eur Heart J 2009; 30: 444-452.
22. van Rossum AC, Visser FC, Hofman MB, Galjee MA, Westerhof N, Valk J,. Global left ventricular perfusion: noninvasive measurement with cine MR imaging and phase velocity mapping of coronary venous outflow. Radiology 1992; 182: 685-691.
23. Koskenvuo JW, Hartiala JJ, Knuuti J, Sakuma H, Toikka JO, Komu M, Saraste M, Niemi P,. Assessing coronary sinus blood flow in patients with coronary artery disease: a comparison of phase-contrast MR imaging with positron emission tomography. Am J Roentgenol 2001; 177: 1161-1166.
24. Kawada N, Sakuma H, Yamakado T, Takeda K, Isaka N, Nakano T, Higgins CB,. Hypertrophic cardiomyopathy: MR measurement of coronary blood flow and vasodilator flow reserve in patients and healthy subjects. Radiology 1999; 211: 129-135.
25. Kennedy K, Dick A, Drangova M, Raval A, Mahoney C, Karlik S, Pflugfelder PW,. Magnetic resonance measurements of coronary flow reserve in heart transplant recipients: an exploratory study of the relationship to coronary angiographic findings. J Cardiovasc Magn Reson 2007; 9: 701-707.
26. Lund GK, Watzinger N, Saeed M, Reddy GP, Yang M, Araoz PA, Curatola D, Bedigian M, Higgins CB,. Chronic heart failure: global left ventricular perfusion and coronary flow reserve with velocity-encoded cine MR imaging: initial results. Radiology 2003; 227: 209-215.
27. Bernstein MA, Zhou XJ, Polzin JA, King KF, Ganin A, Pelc NJ, Glover GH,. Concomitant gradient terms in phase contrast MR: analysis and correction. Magn Reson Med 1998; 39: 300-308.
28. Yoshida K, Mullani N, Gould KL,. Coronary flow and flow reserve by PET simplified for clinical applications using rubidium-82 or nitrogen-13-ammonia. J Nucl Med 1996; 37: 1701-1712.
29. Haunso S, Paaske WP, Sejrsen P, Amtorp O,. Capillary permeability in canine myocardium as determined by bolus injection, residue detection. Acta Physiol Scand 1980; 108: 389-397.
30. Svendsen JH, Kelbaek H, Efsen F, Saunamaki KI, Hoilund-Carlsen PF, Haunso S,. Myocardial blood flow rate and capillary permeability for 99mTc-DTPA in patients with angiographically normal coronary arteries. Evaluation of the single-injection, residue detection method with intracoronary indicator bolus injection and the use of a mobile gamma camera. Cardiology 1994; 85: 161-170.
31. Svendsen JH, Efsen F, Haunso S,. Capillary permeability of 99mTc-DTPA in canine myocardium determined by intracoronary bolus injection and residue detection. Cardiovasc Res 1989; 23: 512-519.
32. Prato FS, Wisenberg G, Marshall TP, Uksik P, Zabel P,. Comparison of the biodistribution of gadolinium-153 DTPA and technetium-99m DTPA in rats. J Nucl Med 1988; 29: 1683-1687.
33. Dilsizian V, Narula J,. Atlas of nuclear cardiology, 2nd ed. Philadelphia: Curent Medicine LLC; 2006. p 32.
34. Schelbert HR, Phelps ME, Huang SC, MacDonald NS, Hansen H, Selin C, Kuhl DE,. N-13 ammonia as an indicator of myocardial blood flow. Circulation 1981; 63: 1259-1272.
35. Hutchins GD, Schwaiger M, Rosenspire KC, Krivokapich J, Schelbert H, Kuhl DE,. Noninvasive quantification of regional blood flow in the human heart using N-13 ammonia and dynamic positron emission tomographic imaging. J Am Coll Cardiol 1990; 15: 1032-1042.
36. Svendsen JH, Efsen F, Haunso S,. Capillary permeability of 99mTc-DTPA and blood flow rate in the human myocardium determined by intracoronary bolus injection and residue detection. Cardiology 1992; 80: 18-27.
37. Huang SC, Williams BA, Krivokapich J, Araujo L, Phelps ME, Schelbert HR,. Rabbit myocardial 82Rb kinetics and a compartmental model for blood flow estimation. Am J Physiol 1989; 256: 1156-1164.
38. Phelps ME, Huang SC, Hoffman EJ, Selin C, Kuhl DE,. Cerebral extraction of N-13 ammonia: its dependence on cerebral blood flow and capillary permeability-surface area product. Stroke 1981; 12: 607-619.
39. Dauber IM, VanBenthuysen KM, McMurtry IF, Wheeler GS, Lesnefsky EJ, Horwitz LD, Weil JV,. Functional coronary microvascular injury evident as increased permeability due to brief ischemia and reperfusion. Circ Res 1990; 66: 986-998.
40. Fritz-Hansen T, Hove JD, Kofoed KF, Kelbaek H, Larsson HB,. Quantification of MRI measured myocardial perfusion reserve in healthy humans: a comparison with positron emission tomography. J Magn Reson Imaging 2008; 27: 818-824.
41. Pärkkä JP, Niemi P, Saraste A, Koskenvuo JW, Komu M, Oikonen V, Toikka JO, Kiviniemi TO, Knuuti J, Sakuma H, Hartiala JJ,. Comparison of MRI and positron emission tomography for measuring myocardial perfusion reserve in healthy humans. Magn Reson Med 2006; 55: 772-779.
42. Ishida M, Sakuma H, Murashima S, Nishida J, Senga M, Kobayasi S, Takeda K, Kato N,. Absolute blood contrast concentration and blood signal saturation on myocardial perfusion MRI: estimation from CT data. J Magn Reson Imaging 2009; 29: 205-210.
43. Tweedle MF, Wedeking P, Telser J, Sotak CH, Chang CA, Kumar K, Wan X, Eaton SM,. Dependence of MR signal intensity on Gd tissue concentration over a broad dose range. Magn Reson Med 1991; 22: 191-194.
44. Pack NA, DiBella EV,. Comparison of myocardial perfusion estimates from dynamic contrast-enhanced magnetic resonance imaging with four quantitative analysis methods. Magn Reson Med 2010; 64: 125-137.
45. Plein S, Schwitter J, Suerder D, Greenwood JP, Boesiger P, Kozerke S,. k-Space and time sensitivity encoding-accelerated myocardial perfusion MR imaging at 3.0 T: comparison with 1.5 T. Radiology. 2008; 249: 493-500.
46. Giesel FL, von Tengg-Kobligk H, Wilkinson ID, Siegler P, von der Lieth CW, Frank M, Lodemann KP, Essig M,. Influence of human serum albumin on longitudinal and transverse relaxation rates (r1 and r2) of magnetic resonance contrast agents. Invest Radiol 2006; 41: 222-228.
47. Eldredge HB, Spiller M, Chasse JM, Greenwood MT, Caravan P,. Species dependence on plasma protein binding and relaxivity of the gadolinium-based MRI contrast agent MS-325. Invest Radiol 2006; 41: 229-243.