메뉴 건너뛰기




Volumn 28, Issue 9, 2011, Pages 1813-1825

Ketogenic diet prevents alterations in brain metabolism in young but not adult rats after traumatic brain injury

Author keywords

ketogenic diet; nuclear magnetic resonance spectroscopy; phosphorus; proton; TBI

Indexed keywords

3 HYDROXYBUTYRIC ACID; ADENOSINE TRIPHOSPHATE; AMINO ACID; CREATINE; CREATINE PHOSPHATE; N ACETYLASPARTIC ACID;

EID: 80054802883     PISSN: 08977151     EISSN: 15579042     Source Type: Journal    
DOI: 10.1089/neu.2011.1822     Document Type: Article
Times cited : (85)

References (81)
  • 1
    • 2442624618 scopus 로고    scopus 로고
    • Poly(ADPribose) polymerase-1-mediated cell death in astrocytes requires NAD+ depletion and mitochondrial permeability transition
    • Alano, C.C., Ying W., and Swanson, R.A. (2004). Poly(ADPribose) polymerase-1-mediated cell death in astrocytes requires NAD+ depletion and mitochondrial permeability transition. J. Biol. Chem. 279, 18,895-18,902.
    • (2004) J. Biol. Chem. , vol.279 , pp. 18895-18902
    • Alano, C.C.1    Ying, W.2    Swanson, R.A.3
  • 2
    • 0034575153 scopus 로고    scopus 로고
    • Low extracellular (ECF) glucose affects the neurochemical profile in severe head-injured patients
    • Alessandri, B., Reinert, M., Young, H.F., and Bullock, R. (2000). Low extracellular (ECF) glucose affects the neurochemical profile in severe head-injured patients. Acta Neurochir. Suppl. 76, 425-430.
    • (2000) Acta Neurochir. Suppl. , vol.76 , pp. 425-430
    • Alessandri, B.1    Reinert, M.2    Young, H.F.3    Bullock, R.4
  • 4
    • 0026738714 scopus 로고
    • Functional compartmentalization of energy production in neural tissue
    • Andersen, B.J., and Marmarou, A. (1992). Functional compartmentalization of energy production in neural tissue. Brain Res. 585, 190-195.
    • (1992) Brain Res. , vol.585 , pp. 190-195
    • Andersen, B.J.1    Marmarou, A.2
  • 5
    • 64849096855 scopus 로고    scopus 로고
    • The effects of a ketogenic diet on behavioral outcome after controlled cortical impact injury in the juvenile and adult rat
    • Appelberg, K.S., Hovda, D.A., and Prins, M.L. (2009). The effects of a ketogenic diet on behavioral outcome after controlled cortical impact injury in the juvenile and adult rat. J. Neurotrauma 26, 497-506.
    • (2009) J. Neurotrauma , vol.26 , pp. 497-506
    • Appelberg, K.S.1    Hovda, D.A.2    Prins, M.L.3
  • 6
    • 33751394647 scopus 로고    scopus 로고
    • Susceptibility-weighted imaging and proton magnetic resonance spectroscopy in assessment of outcome after pediatric traumatic brain injury
    • Ashwal, S., Babikian, T., Gardner-Nichols, J., Freier, M.C., Tong, K.A., and Holshouser, B.A. (2006). Susceptibility-weighted imaging and proton magnetic resonance spectroscopy in assessment of outcome after pediatric traumatic brain injury. Arch. Phys. Med. Rehabil. 87, S50-58.
    • (2006) Arch. Phys. Med. Rehabil. , vol.87
    • Ashwal, S.1    Babikian, T.2    Gardner-Nichols, J.3    Freier, M.C.4    Tong, K.A.5    Holshouser, B.A.6
  • 7
    • 27444445186 scopus 로고    scopus 로고
    • Upregulation of pentose phosphate pathway and preservation of tricarboxylic acid cycle flux after experimental brain injury
    • Bartnik, B.L., Sutton, R.L., Fukushima, M., Harris, N.G., Hovda, D.A., and Lee, S.M. (2005). Upregulation of pentose phosphate pathway and preservation of tricarboxylic acid cycle flux after experimental brain injury. J. Neurotrauma 22, 1052-1065.
    • (2005) J. Neurotrauma , vol.22 , pp. 1052-1065
    • Bartnik, B.L.1    Sutton, R.L.2    Fukushima, M.3    Harris, N.G.4    Hovda, D.A.5    Lee, S.M.6
  • 8
    • 0029767436 scopus 로고    scopus 로고
    • Inhibition of N-acetylaspartate production: Implications for 1H MRS studies in vivo
    • Bates, T.E., Strangward, M., Keelan, J., Davey, G.P., Munro, P.M., and Clark, J.B. (1996). Inhibition of N-acetylaspartate production: Implications for 1H MRS studies in vivo. Neuroreport 7, 1397-1400.
    • (1996) Neuroreport , vol.7 , pp. 1397-1400
    • Bates, T.E.1    Strangward, M.2    Keelan, J.3    Davey, G.P.4    Munro, P.M.5    Clark, J.B.6
  • 9
    • 0034623332 scopus 로고    scopus 로고
    • Glutamine synthetase activities in spinal white and gray matter 7 days following spinal cord injury in rats
    • Benton, R.L., Ross, C.D., and Miller, K.E. (2000). Glutamine synthetase activities in spinal white and gray matter 7 days following spinal cord injury in rats. Neurosci. Lett. 291, 1-4.
    • (2000) Neurosci. Lett. , vol.291 , pp. 1-4
    • Benton, R.L.1    Ross, C.D.2    Miller, K.E.3
  • 10
    • 0021997074 scopus 로고
    • Poly(ADP-ribose) in the cellular response to DNA damage
    • Berger, N.A. (1985). Poly(ADP-ribose) in the cellular response to DNA damage. Radiat. Res. 101, 4-15.
    • (1985) Radiat. Res. , vol.101 , pp. 4-15
    • Berger, N.A.1
  • 12
    • 18244397928 scopus 로고    scopus 로고
    • Seizure-associated abnormalities in epilepsy: Evidence from MR imaging
    • Briellmann, R.S., Wellard, R.M., and Jackson, G.D. (2005). Seizure-associated abnormalities in epilepsy: Evidence from MR imaging. Epilepsia 46, 760-766.
    • (2005) Epilepsia , vol.46 , pp. 760-766
    • Briellmann, R.S.1    Wellard, R.M.2    Jackson, G.D.3
  • 13
  • 14
    • 0032891802 scopus 로고    scopus 로고
    • Relationship between neurometabolite derangement and neurocognitive dysfunction in systemic lupus erythematosus
    • Brooks, W.M., Jung, R.E., Ford, C.C., Greinel, E.J., and Sibbitt, W.L., Jr. (1999). Relationship between neurometabolite derangement and neurocognitive dysfunction in systemic lupus erythematosus. J. Rheumatol. 26, 81-85.
    • (1999) J. Rheumatol. , vol.26 , pp. 81-85
    • Brooks, W.M.1    Jung, R.E.2    Ford, C.C.3    Greinel, E.J.4    Sibbitt Jr., W.L.5
  • 16
    • 27644594658 scopus 로고    scopus 로고
    • 1H-MRS quantification of tNA and tCr in patients with multiple sclerosis: A meta-analytic review
    • Caramanos, Z., Narayanan, S., and Arnold, D.L. (2005). 1H-MRS quantification of tNA and tCr in patients with multiple sclerosis: A meta-analytic review. Brain 128, 2483-2506.
    • (2005) Brain , vol.128 , pp. 2483-2506
    • Caramanos, Z.1    Narayanan, S.2    Arnold, D.L.3
  • 17
    • 0031978978 scopus 로고    scopus 로고
    • High-field proton magnetic resonance spectroscopy of a swine model for axonal injury
    • Cecil, K.M., Lenkinski, R.E., Meaney, D.F., McIntosh, T.K., and Smith, D.H. (1998). High-field proton magnetic resonance spectroscopy of a swine model for axonal injury. J. Neurochem. 70, 2038-2044.
    • (1998) J. Neurochem. , vol.70 , pp. 2038-2044
    • Cecil, K.M.1    Lenkinski, R.E.2    Meaney, D.F.3    McIntosh, T.K.4    Smith, D.H.5
  • 18
    • 0031731910 scopus 로고    scopus 로고
    • N-acetyl aspartate: A marker for neuronal loss or mitochondrial dysfunction
    • Clark, J. B. (1998). N-acetyl aspartate: A marker for neuronal loss or mitochondrial dysfunction. Dev. Neurosci. 20, 271-276.
    • (1998) Dev. Neurosci. , vol.20 , pp. 271-276
    • Clark, J.B.1
  • 19
    • 0028792005 scopus 로고
    • Reversible decreases in N-acetylaspartate after acute brain injury
    • De Stefano, N., Matthews, P.M., and Arnold, D.L. (1995). Reversible decreases in N-acetylaspartate after acute brain injury. Magn. Reson. Med. 34, 721-727.
    • (1995) Magn. Reson. Med. , vol.34 , pp. 721-727
    • De Stefano, N.1    Matthews, P.M.2    Arnold, D.L.3
  • 21
    • 0024365739 scopus 로고
    • The role of excitatory amino acids and NMDA receptors in traumatic brain injury
    • Faden, A.I., Demediuk, P., Panter, S.S., and Vink, R. (1989). The role of excitatory amino acids and NMDA receptors in traumatic brain injury. Science 244, 798-800.
    • (1989) Science , vol.244 , pp. 798-800
    • Faden, A.I.1    Demediuk, P.2    Panter, S.S.3    Vink, R.4
  • 22
    • 0035076448 scopus 로고    scopus 로고
    • Decrease and recovery of N-acetylaspartate/creatine in rat brain remote from focal injury
    • Gasparovic, C., Arfai, N., Smid, N., and Feeney, D.M. (2001). Decrease and recovery of N-acetylaspartate/creatine in rat brain remote from focal injury. J. Neurotrauma 18, 241-246.
    • (2001) J. Neurotrauma , vol.18 , pp. 241-246
    • Gasparovic, C.1    Arfai, N.2    Smid, N.3    Feeney, D.M.4
  • 23
    • 0020367858 scopus 로고
    • P-31 nuclear magnetic resonance analysis of brain: The perchloric acid extract spectrum
    • Glonek, T., Kopp, S.J., Kot, E., Pettegrew, J.W., Harrison, W.H., and Cohen, M.M. (1982). P-31 nuclear magnetic resonance analysis of brain: The perchloric acid extract spectrum. J. Neurochem. 39, 1210-1219.
    • (1982) J. Neurochem. , vol.39 , pp. 1210-1219
    • Glonek, T.1    Kopp, S.J.2    Kot, E.3    Pettegrew, J.W.4    Harrison, W.H.5    Cohen, M.M.6
  • 24
    • 0032879143 scopus 로고    scopus 로고
    • Extracellular lactate and glucose alterations in the brain after head injury measured by microdialysis
    • Goodman, J.C., Valadka, A.B., Gopinath, S.P., Uzura, M., and Robertson, C.S. (1999). Extracellular lactate and glucose alterations in the brain after head injury measured by microdialysis. Crit. Care Med. 27, 1965-1973.
    • (1999) Crit. Care Med. , vol.27 , pp. 1965-1973
    • Goodman, J.C.1    Valadka, A.B.2    Gopinath, S.P.3    Uzura, M.4    Robertson, C.S.5
  • 25
    • 0031011669 scopus 로고    scopus 로고
    • Glutamine synthetase protects against neuronal degeneration in injured retinal tissue
    • Gorovits, R., Avidan, N., Avisar, N., Shaked, I., and Vardimon, L. (1997). Glutamine synthetase protects against neuronal degeneration in injured retinal tissue. Proc. Natl. Acad. Sci. U. S. A. 94, 7024-7029.
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 7024-7029
    • Gorovits, R.1    Avidan, N.2    Avisar, N.3    Shaked, I.4    Vardimon, L.5
  • 26
    • 0016177858 scopus 로고
    • Focused microwave radiation: A technique to minimize post mortem changes of cyclic nucleotides, dopa and choline and to preserve brain morphology
    • Guidotti, A., Cheney, D.L., Trabucchi, M., Doteuchi, M., and Wang, C. (1974). Focused microwave radiation: A technique to minimize post mortem changes of cyclic nucleotides, dopa and choline and to preserve brain morphology. Neuropharmacology 13, 1115-1122.
    • (1974) Neuropharmacology , vol.13 , pp. 1115-1122
    • Guidotti, A.1    Cheney, D.L.2    Trabucchi, M.3    Doteuchi, M.4    Wang, C.5
  • 27
    • 43049127389 scopus 로고    scopus 로고
    • Antioxidant capacity contributes to protection of ketone bodies against oxidative damage induced during hypoglycemic conditions
    • Haces, M.L., Hernandez-Fonseca, K., Medina-Campos, O.N., Montiel, T., Pedraza-Chaverri, J., and Massieu, L. (2008). Antioxidant capacity contributes to protection of ketone bodies against oxidative damage induced during hypoglycemic conditions. Exp. Neurol. 211, 85-96.
    • (2008) Exp. Neurol. , vol.211 , pp. 85-96
    • Haces, M.L.1    Hernandez-Fonseca, K.2    Medina-Campos, O.N.3    Montiel, T.4    Pedraza-Chaverri, J.5    Massieu, L.6
  • 28
    • 0029823016 scopus 로고    scopus 로고
    • Metabolite changes in the cerebral cortex of treated and untreated infant hydrocephalic rats studied using in vitro 31PNMR spectroscopy
    • Harris, N.G., Plant, H.D., Briggs, R.W., and Jones, H.C. (1996). Metabolite changes in the cerebral cortex of treated and untreated infant hydrocephalic rats studied using in vitro 31PNMR spectroscopy. J. Neurochem. 67, 2030-2038.
    • (1996) J. Neurochem. , vol.67 , pp. 2030-2038
    • Harris, N.G.1    Plant, H.D.2    Briggs, R.W.3    Jones, H.C.4
  • 29
    • 0031037782 scopus 로고    scopus 로고
    • Neurochemical changes in the cerebral cortex of treated and untreated hydrocephalic rat pups quantified with in vitro 1H-NMR spectroscopy
    • Harris, N.G., Plant, H.D., Inglis, B.A., Briggs, R.W., and Jones, H.C. (1997). Neurochemical changes in the cerebral cortex of treated and untreated hydrocephalic rat pups quantified with in vitro 1H-NMR spectroscopy. J. Neurochem. 68, 305-312.
    • (1997) J. Neurochem. , vol.68 , pp. 305-312
    • Harris, N.G.1    Plant, H.D.2    Inglis, B.A.3    Briggs, R.W.4    Jones, H.C.5
  • 30
    • 0025616475 scopus 로고
    • The increase in local cerebral glucose utilization following fluid percussion brain injury is prevented with kynurenic acid and is associated with an increase in calcium
    • Hovda, D.A., Yoshino, A., Kawamata, T., Katayama, Y., Fineman, I., and Becker, D.P. (1990). The increase in local cerebral glucose utilization following fluid percussion brain injury is prevented with kynurenic acid and is associated with an increase in calcium. Acta Neurochir. Suppl. (Wien) 51, 331-333.
    • (1990) Acta Neurochir. Suppl. (Wien , vol.51 , pp. 331-333
    • Hovda, D.A.1    Yoshino, A.2    Kawamata, T.3    Katayama, Y.4    Fineman, I.5    Becker, D.P.6
  • 31
    • 60249102843 scopus 로고    scopus 로고
    • Ketogenic diet reduces cytochrome c release and cellular apoptosis following traumatic brain injury in juvenile rats
    • Hu, Z.G., Wang, H.D., Jin, W., and Yin, H.X. (2009). Ketogenic diet reduces cytochrome c release and cellular apoptosis following traumatic brain injury in juvenile rats. Ann. Clin. Lab. Sci. 39, 76-83.
    • (2009) Ann. Clin. Lab. Sci. , vol.39 , pp. 76-83
    • Hu, Z.G.1    Wang, H.D.2    Jin, W.3    Yin, H.X.4
  • 32
    • 0025616746 scopus 로고
    • Early cellular swelling in experimental traumatic brain injury: A phenomenon mediated by excitatory amino acids
    • Katayama, Y., Becker, D.P., Tamura, T., and Ikezaki, K. (1990). Early cellular swelling in experimental traumatic brain injury: A phenomenon mediated by excitatory amino acids. Acta Neurochir. Suppl. (Wien) 51, 271-273.
    • (1990) Acta Neurochir. Suppl. (Wien , vol.51 , pp. 271-273
    • Katayama, Y.1    Becker, D.P.2    Tamura, T.3    Ikezaki, K.4
  • 33
    • 0028879714 scopus 로고
    • Role of excitatory amino acid-mediated ionic fluxes in traumatic brain injury
    • Katayama, Y., Maeda, T., Koshinaga, M., Kawamata, T., and Tsubokawa, T. (1995). Role of excitatory amino acid-mediated ionic fluxes in traumatic brain injury. Brain Pathol. 5, 427-435.
    • (1995) Brain Pathol. , vol.5 , pp. 427-435
    • Katayama, Y.1    Maeda, T.2    Koshinaga, M.3    Kawamata, T.4    Tsubokawa, T.5
  • 34
    • 0026504549 scopus 로고
    • Administration of excitatory amino acid antagonists via microdialysis attenuates the increase in glucose utilization seen following concussive brain injury
    • Kawamata, T., Katayama, Y., Hovda, D.A., Yoshino, A., and Becker, D.P. (1992). Administration of excitatory amino acid antagonists via microdialysis attenuates the increase in glucose utilization seen following concussive brain injury. J. Cereb. Blood Flow Metab. 12, 12-24.
    • (1992) J. Cereb. Blood Flow Metab. , vol.12 , pp. 12-24
    • Kawamata, T.1    Katayama, Y.2    Hovda, D.A.3    Yoshino, A.4    Becker, D.P.5
  • 35
    • 0025284999 scopus 로고
    • Metabolic and hemodynamic activation of postischemic rat brain by cortical spreading depression
    • Kocher, M. (1990). Metabolic and hemodynamic activation of postischemic rat brain by cortical spreading depression. J. Cereb. Blood Flow Metab. 10, 564-571.
    • (1990) J. Cereb. Blood Flow Metab. , vol.10 , pp. 564-571
    • Kocher, M.1
  • 37
    • 0033392346 scopus 로고    scopus 로고
    • Evidence for energy failure following irreversible traumatic brain injury
    • Lee, S.M., Wong, M.D., Samii, A., and Hovda, D.A. (1999). Evidence for energy failure following irreversible traumatic brain injury. Ann. N. Y. Acad. Sci. 893, 337-340.
    • (1999) Ann. N. Y. Acad. Sci. , vol.893 , pp. 337-340
    • Lee, S.M.1    Wong, M.D.2    Samii, A.3    Hovda, D.A.4
  • 38
    • 71749099555 scopus 로고    scopus 로고
    • High extracellular glutamate modulates expression of glutamate transporters and glutamine synthetase in cultured astrocytes
    • Lehmann, C., Bette, S., and Engele, J. (2009). High extracellular glutamate modulates expression of glutamate transporters and glutamine synthetase in cultured astrocytes. Brain Res. 1297, 1-8.
    • (2009) Brain Res. , vol.1297 , pp. 1-8
    • Lehmann, C.1    Bette, S.2    Engele, J.3
  • 39
    • 33846852428 scopus 로고    scopus 로고
    • Ketones inhibit mitochondrial production of reactive oxygen species production following glutamate excitotoxicity by increasing NADH oxidation
    • Maalouf, M., Sullivan, P.G., Davis, L., Kim, D.Y., and Rho, J.M. (2007). Ketones inhibit mitochondrial production of reactive oxygen species production following glutamate excitotoxicity by increasing NADH oxidation. Neuroscience 145, 256-264.
    • (2007) Neuroscience , vol.145 , pp. 256-264
    • Maalouf, M.1    Sullivan, P.G.2    Davis, L.3    Kim, D.Y.4    Rho, J.M.5
  • 40
    • 33748208836 scopus 로고    scopus 로고
    • Energy metabolic changes in the early post-injury period following traumatic brain injury in rats
    • Marklund, N., Salci, K., Ronquist, G., and Hillered, L. (2006). Energy metabolic changes in the early post-injury period following traumatic brain injury in rats. Neurochem. Res. 31, 1085-1093.
    • (2006) Neurochem. Res. , vol.31 , pp. 1085-1093
    • Marklund, N.1    Salci, K.2    Ronquist, G.3    Hillered, L.4
  • 42
    • 0030061356 scopus 로고    scopus 로고
    • Exogenous glutamate concentration regulates the metabolic fate of glutamate in astrocytes
    • McKenna, M.C., Sonnewald, U., Huang, X., Stevenson, J., and Zielke, H.R. (1996). Exogenous glutamate concentration regulates the metabolic fate of glutamate in astrocytes. J. Neurochem. 66, 386-393.
    • (1996) J. Neurochem. , vol.66 , pp. 386-393
    • McKenna, M.C.1    Sonnewald, U.2    Huang, X.3    Stevenson, J.4    Zielke, H.R.5
  • 43
    • 0016465971 scopus 로고
    • The levels of labile intermediary metabolites in mouse brain following rapid tissue fixation with microwave irradiation
    • Medina, M.A., Jones, D.J., Stavinoha, W.B., and Ross, D.H. (1975). The levels of labile intermediary metabolites in mouse brain following rapid tissue fixation with microwave irradiation. J. Neurochem. 24, 223-227.
    • (1975) J. Neurochem. , vol.24 , pp. 223-227
    • Medina, M.A.1    Jones, D.J.2    Stavinoha, W.B.3    Ross, D.H.4
  • 44
    • 0024235125 scopus 로고
    • Study on influence of inactivation enzyme techniques and extraction procedures on cerebral phosphorylated metabolite levels by 31P NMR spectroscopy
    • Miccheli, A., Aureli, T., Delfini, M., Di Cocco, M.E., Viola, P., Gobetto, R., and Conti, F. (1988). Study on influence of inactivation enzyme techniques and extraction procedures on cerebral phosphorylated metabolite levels by 31P NMR spectroscopy. Cell Mol. Biol. 34, 591-603.
    • (1988) Cell Mol. Biol. , vol.34 , pp. 591-603
    • Miccheli, A.1    Aureli, T.2    Delfini, M.3    Di Cocco, M.E.4    Viola, P.5    Gobetto, R.6    Conti, F.7
  • 45
    • 0029942903 scopus 로고    scopus 로고
    • Origin of cholesterol in myelin
    • Morell, P., and Jurevics, H. (1996). Origin of cholesterol in myelin. Neurochem. Res. 21, 463-470.
    • (1996) Neurochem. Res. , vol.21 , pp. 463-470
    • Morell, P.1    Jurevics, H.2
  • 46
    • 0023677396 scopus 로고
    • Quantitative autoradiographic measurement of local cerebral glucose utilization in freely moving rats during postnatal development
    • Nehlig, A., de Vasconcelos, A.P., and Boyet, S. (1988). Quantitative autoradiographic measurement of local cerebral glucose utilization in freely moving rats during postnatal development. J. Neurosci. 8, 2321-2333.
    • (1988) J. Neurosci. , vol.8 , pp. 2321-2333
    • Nehlig, A.1    De Vasconcelos, A.P.2    Boyet, S.3
  • 47
    • 85052608636 scopus 로고    scopus 로고
    • Glucose metabolism in traumatic brain injury: A combined microdialysis and [18F]-2-fluoro-2-deoxy-D-glucosepositron emission tomography (FDG-PET) study
    • O'Connell, M.T., Seal, A., Nortje, J., Al-Rawi, P.G., Coles, J.P., Fryer, T.D., Menon, D.K., Pickard, J.D., and Hutchinson, P.J. (2005). Glucose metabolism in traumatic brain injury: A combined microdialysis and [18F]-2-fluoro-2-deoxy-D-glucosepositron emission tomography (FDG-PET) study. Acta Neurochir. Suppl. 95, 165-168.
    • (2005) Acta Neurochir. Suppl. , vol.95 , pp. 165-168
    • O'Connell, M.T.1    Seal, A.2    Nortje, J.3    Al-Rawi, P.G.4    Coles, J.P.5    Fryer, T.D.6    Menon, D.K.7    Pickard, J.D.8    Hutchinson, P.J.9
  • 51
    • 0026598727 scopus 로고
    • Brain glutamine synthetase increases following cerebral ischemia in the rat
    • Petito, C.K., Chung, M.C., Verkhovsky, L.M., and Cooper, A.J. (1992). Brain glutamine synthetase increases following cerebral ischemia in the rat. Brain Res. 569, 275-280.
    • (1992) Brain Res. , vol.569 , pp. 275-280
    • Petito, C.K.1    Chung, M.C.2    Verkhovsky, L.M.3    Cooper, A.J.4
  • 52
    • 69249101222 scopus 로고    scopus 로고
    • The effects of age and ketogenic diet on local cerebral metabolic rates of glucose after controlled cortical impact injury in rats
    • Prins, M., and Hovda, D. (2009). The effects of age and ketogenic diet on local cerebral metabolic rates of glucose after controlled cortical impact injury in rats. J. Neurotrauma 26, 1083-1093.
    • (2009) J. Neurotrauma , vol.26 , pp. 1083-1093
    • Prins, M.1    Hovda, D.2
  • 53
    • 37549064016 scopus 로고    scopus 로고
    • Cerebral metabolic adaptation and ketone metabolismafter brain injury
    • Prins, M.L. (2008). Cerebral metabolic adaptation and ketone metabolismafter brain injury. J. Cereb. Blood Flow Metab. 28, 1-16.
    • (2008) J. Cereb. Blood Flow Metab. , vol.28 , pp. 1-16
    • Prins, M.L.1
  • 54
    • 33748186181 scopus 로고    scopus 로고
    • Induction of monocarboxylate transporter 2 expression and ketone transport following traumatic brain injury in juvenile and adult rats
    • Prins, M. L., and Giza, C.C. (2006). Induction of monocarboxylate transporter 2 expression and ketone transport following traumatic brain injury in juvenile and adult rats. Dev. Neurosci. 28, 447-456.
    • (2006) Dev. Neurosci. , vol.28 , pp. 447-456
    • Prins, M.L.1    Giza, C.C.2
  • 55
    • 27644461807 scopus 로고    scopus 로고
    • Agedependent reduction of cortical contusion volume by ketones after traumatic brain injury
    • Prins, M.L., Fujima, L.S., and Hovda, D.A. (2005). Agedependent reduction of cortical contusion volume by ketones after traumatic brain injury. J. Neurosci. Res. 82, 413-420.
    • (2005) J. Neurosci. Res. , vol.82 , pp. 413-420
    • Prins, M.L.1    Fujima, L.S.2    Hovda, D.A.3
  • 56
    • 3343008579 scopus 로고    scopus 로고
    • Increased cerebral uptake and oxidation of exogenous betaHB improves ATP following traumatic brain injury in adult rats
    • Prins, M.L., Lee, S.M., Fujima, L.S., and Hovda, D.A. (2004). Increased cerebral uptake and oxidation of exogenous betaHB improves ATP following traumatic brain injury in adult rats. J. Neurochem. 90, 666-672.
    • (2004) J. Neurochem. , vol.90 , pp. 666-672
    • Prins, M.L.1    Lee, S.M.2    Fujima, L.S.3    Hovda, D.A.4
  • 57
    • 3242799212 scopus 로고    scopus 로고
    • In vivo neuroprotective adaptation of the glutamate/glutamine cycle to neuronal death
    • Ramonet, D., Rodriguez, M.J., Fredriksson, K., Bernal, F., and Mahy, N. (2004). In vivo neuroprotective adaptation of the glutamate/glutamine cycle to neuronal death. Hippocampus 14, 586-594.
    • (2004) Hippocampus , vol.14 , pp. 586-594
    • Ramonet, D.1    Rodriguez, M.J.2    Fredriksson, K.3    Bernal, F.4    Mahy, N.5
  • 58
    • 0032878018 scopus 로고    scopus 로고
    • Age-dependent differences in flurothyl seizure sensitivity in mice treated with a ketogenic diet
    • Rho, J.M., Kim, D.W., Robbins, C.A., Anderson, G.D., and Schwartzkroin, P.A. (1999). Age-dependent differences in flurothyl seizure sensitivity in mice treated with a ketogenic diet. Epilepsy Res. 37, 233-240.
    • (1999) Epilepsy Res. , vol.37 , pp. 233-240
    • Rho, J.M.1    Kim, D.W.2    Robbins, C.A.3    Anderson, G.D.4    Schwartzkroin, P.A.5
  • 60
    • 77949526140 scopus 로고    scopus 로고
    • Reduced pain and inflammation in juvenile and adult rats fed a ketogenic diet
    • Ruskin, D.N., Kawamura, M., and Masino, S.A. (2009). Reduced pain and inflammation in juvenile and adult rats fed a ketogenic diet. PLoS One 4, e8349.
    • (2009) PLoS One , vol.4
    • Ruskin, D.N.1    Kawamura, M.2    Masino, S.A.3
  • 61
    • 0037997172 scopus 로고    scopus 로고
    • A dual role for poly-ADP-ribosylation in spatial memory acquisition after traumatic brain injury in mice involving NAD+ depletion and ribosylation of 14-3-3gamma
    • Satchell, M.A., Zhang, X., Kochanek, P.M., Dixon, C.E., Jenkins, L.W., Melick, J., Szabo, C., and Clark, R.S. (2003). A dual role for poly-ADP-ribosylation in spatial memory acquisition after traumatic brain injury in mice involving NAD+ depletion and ribosylation of 14-3-3gamma. J. Neurochem. 85, 697-708.
    • (2003) J. Neurochem. , vol.85 , pp. 697-708
    • Satchell, M.A.1    Zhang, X.2    Kochanek, P.M.3    Dixon, C.E.4    Jenkins, L.W.5    Melick, J.6    Szabo, C.7    Clark, R.S.8
  • 62
    • 64349119563 scopus 로고    scopus 로고
    • Delayed cerebral oxidative glucose metabolism after traumatic brain injury in young rats
    • Scafidi, S., O'Brien, J., Hopkins, I., Robertson, C., Fiskum, G., and McKenna, M. (2009). Delayed cerebral oxidative glucose metabolism after traumatic brain injury in young rats. J. Neurochem. 109, Suppl. 1, 189-197.
    • (2009) J. Neurochem. , vol.109 , Issue.SUPPL. 1 , pp. 189-197
    • Scafidi, S.1    O'Brien, J.2    Hopkins, I.3    Robertson, C.4    Fiskum, G.5    McKenna, M.6
  • 63
    • 0041464462 scopus 로고    scopus 로고
    • Metabolic changes in the vicinity of brain contusions: A proton magnetic resonance spectroscopy and histology study
    • Schuhmann, M.U., Stiller, D., Skardelly, M., Bernarding, J., Klinge, P.M., Samii, A., Samii, M., and Brinker, T. (2003). Metabolic changes in the vicinity of brain contusions: A proton magnetic resonance spectroscopy and histology study. J. Neurotrauma 20, 725-743.
    • (2003) J. Neurotrauma , vol.20 , pp. 725-743
    • Schuhmann, M.U.1    Stiller, D.2    Skardelly, M.3    Bernarding, J.4    Klinge, P.M.5    Samii, A.6    Samii, M.7    Brinker, T.8
  • 65
    • 0017913377 scopus 로고
    • Use of microwave irradiation to prevent postmortem catecholamine metabolism: Evidence for tissue disruption artifact in a discrete region of rat brain
    • Sharpless, N.S., and Brown, L.L. (1978). Use of microwave irradiation to prevent postmortem catecholamine metabolism: Evidence for tissue disruption artifact in a discrete region of rat brain. Brain Res. 140, 171-176.
    • (1978) Brain Res. , vol.140 , pp. 171-176
    • Sharpless, N.S.1    Brown, L.L.2
  • 66
    • 0034194361 scopus 로고    scopus 로고
    • Zincinduced cortical neuronal death: Contribution of energy failure attributable to loss of NAD( + ) and inhibition of glycolysis
    • Sheline, C.T., Behrens, M.M., and Choi, D.W. (2000). Zincinduced cortical neuronal death: Contribution of energy failure attributable to loss of NAD( + ) and inhibition of glycolysis. J. Neurosci. 20, 3139-3146.
    • (2000) J. Neurosci. , vol.20 , pp. 3139-3146
    • Sheline, C.T.1    Behrens, M.M.2    Choi, D.W.3
  • 67
    • 73449092799 scopus 로고    scopus 로고
    • Transient alterations of creatine, creatine phosphate, N-acetylaspartate and high-energy phosphates after mild traumatic brain injury in the rat
    • Signoretti, S., Di Pietro, V., Vagnozzi, R., Lazzarino, G., Amorini, A.M., Belli, A., D'Urso, S., and Tavazzi, B. (2010). Transient alterations of creatine, creatine phosphate, N-acetylaspartate and high-energy phosphates after mild traumatic brain injury in the rat. Mol. Cell Biochem. 333, 269-277.
    • (2010) Mol. Cell Biochem. , vol.333 , pp. 269-277
    • Signoretti, S.1    Di Pietro, V.2    Vagnozzi, R.3    Lazzarino, G.4    Amorini, A.M.5    Belli, A.6    D'Urso, S.7    Tavazzi, B.8
  • 68
    • 0034782504 scopus 로고    scopus 로고
    • N-Acetylaspartate reduction as a measure of injury severity and mitochondrial dysfunction following diffuse traumatic brain injury
    • Signoretti, S., Marmarou, A., Tavazzi, B., Lazzarino, G., Beaumont, A., and Vagnozzi, R. (2001). N-Acetylaspartate reduction as a measure of injury severity and mitochondrial dysfunction following diffuse traumatic brain injury. J. Neurotrauma 18, 977-991.
    • (2001) J. Neurotrauma , vol.18 , pp. 977-991
    • Signoretti, S.1    Marmarou, A.2    Tavazzi, B.3    Lazzarino, G.4    Beaumont, A.5    Vagnozzi, R.6
  • 71
    • 0028253509 scopus 로고
    • Metabolic changes following cortical contusion: Relationships to edema and morphological changes
    • Sutton, R.L., Hovda, D.A., Adelson, P.D., Benzel, E.C., and Becker, D.P. (1994) Metabolic changes following cortical contusion: Relationships to edema and morphological changes. Acta Neurochir. Suppl. (Wien) 60, 446-448.
    • (1994) Acta Neurochir. Suppl. (Wien , vol.60 , pp. 446-448
    • Sutton, R.L.1    Hovda, D.A.2    Adelson, P.D.3    Benzel, E.C.4    Becker, D.P.5
  • 72
    • 0027201877 scopus 로고
    • Unilateral cortical contusion injury in the rat: Vascular disruption and temporal development of cortical necrosis
    • Sutton, R.L., Lescaudron, L., and Stein, D.G. (1993). Unilateral cortical contusion injury in the rat: Vascular disruption and temporal development of cortical necrosis. J. Neurotrauma 10, 135-149.
    • (1993) J. Neurotrauma , vol.10 , pp. 135-149
    • Sutton, R.L.1    Lescaudron, L.2    Stein, D.G.3
  • 73
    • 0015156283 scopus 로고
    • Pitfalls in the use of rapid freezing for stopping brain and spinal cord metabolism in rat and mouse
    • Swaab, D.F. (1971). Pitfalls in the use of rapid freezing for stopping brain and spinal cord metabolism in rat and mouse. J. Neurochem. 18, 2085-2092.
    • (1971) J. Neurochem. , vol.18 , pp. 2085-2092
    • Swaab, D.F.1
  • 75
    • 0033866784 scopus 로고    scopus 로고
    • Cerebral metabolic response to traumatic brain injury sustained early in development: A 2-deoxy-D-glucose autoradiographic study
    • Thomas, S., Prins, M.L., Samii, M., and Hovda, D.A. (2000). Cerebral metabolic response to traumatic brain injury sustained early in development: A 2-deoxy-D-glucose autoradiographic study. J. Neurotrauma 17, 649-665.
    • (2000) J. Neurotrauma , vol.17 , pp. 649-665
    • Thomas, S.1    Prins, M.L.2    Samii, M.3    Hovda, D.A.4
  • 78
    • 0027933397 scopus 로고
    • Bioenergetic analysis of oxidative metabolism following traumatic brain injury in rats
    • Vink, R., Golding, E.M., and Headrick, J.P. (1994). Bioenergetic analysis of oxidative metabolism following traumatic brain injury in rats. J. Neurotrauma 11, 265-274.
    • (1994) J. Neurotrauma , vol.11 , pp. 265-274
    • Vink, R.1    Golding, E.M.2    Headrick, J.P.3
  • 79
    • 0031038634 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and calcium perturbation induced by traumatic brain injury
    • Xiong, Y., Gu, Q., Peterson, P.L., Muizelaar, J.P., and Lee, C.P. (1997). Mitochondrial dysfunction and calcium perturbation induced by traumatic brain injury. J. Neurotrauma 14, 23-34.
    • (1997) J. Neurotrauma , vol.14 , pp. 23-34
    • Xiong, Y.1    Gu, Q.2    Peterson, P.L.3    Muizelaar, J.P.4    Lee, C.P.5
  • 80
    • 0041573041 scopus 로고    scopus 로고
    • NAD+ repletion prevents PARP-1-induced glycolytic blockade and cell death in cultured mouse astrocytes
    • Ying, W., Garnier, P., and Swanson, R.A. (2003). NAD+ repletion prevents PARP-1-induced glycolytic blockade and cell death in cultured mouse astrocytes. Biochem. Biophys. Res. Commun. 308, 809-813.
    • (2003) Biochem. Biophys. Res. Commun. , vol.308 , pp. 809-813
    • Ying, W.1    Garnier, P.2    Swanson, R.A.3
  • 81
    • 0026048155 scopus 로고
    • Dynamic changes in local cerebral glucose utilization following cerebral conclusion in rats: Evidence of a hyper-and subsequent hypometabolic state
    • Yoshino, A., Hovda, D.A., Kawamata, T., Katayama, Y., and Becker, D.P. (1991). Dynamic changes in local cerebral glucose utilization following cerebral conclusion in rats: Evidence of a hyper-and subsequent hypometabolic state. Brain Res. 561, 106-119.
    • (1991) Brain Res. , vol.561 , pp. 106-119
    • Yoshino, A.1    Hovda, D.A.2    Kawamata, T.3    Katayama, Y.4    Becker, D.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.