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Volumn 339, Issue 2, 2011, Pages 618-623

Neuroprotection with a brain-penetrating biologic tumor necrosis factor inhibitor

Author keywords

[No Author keywords available]

Indexed keywords

AMPHETAMINE; APOMORPHINE; CHIMERIC MONOCLONAL ANTIBODY AGAINST MOUSE TRANSFERRIN RECEPTOR TUMOR NECROSIS FACTOR RECEPTOR FUSION PROTEIN; ETANERCEPT; HYBRID PROTEIN; OXIDOPAMINE; TUMOR NECROSIS FACTOR ALPHA INHIBITOR; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG;

EID: 80054788511     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.111.185876     Document Type: Article
Times cited : (51)

References (29)
  • 1
    • 77952329581 scopus 로고    scopus 로고
    • Drug targeting of erythropoietin across the primate blood-brain barrier with an IgG molecular Trojan horse
    • Boado RJ, Hui EK, Lu JZ, and Pardridge WM (2010) Drug targeting of erythropoietin across the primate blood-brain barrier with an IgG molecular Trojan horse. J Pharmacol Exp Ther 333:961-969.
    • (2010) J Pharmacol Exp Ther , vol.333 , pp. 961-969
    • Boado, R.J.1    Hui, E.K.2    Lu, J.Z.3    Pardridge, W.M.4
  • 2
    • 60549101321 scopus 로고    scopus 로고
    • Engineering and expression of a chimeric transferrin receptor monoclonal antibody for blood-brain barrier delivery in the mouse
    • Boado RJ, Zhang Y, Wang Y, and Pardridge WM (2009) Engineering and expression of a chimeric transferrin receptor monoclonal antibody for blood-brain barrier delivery in the mouse. Biotechnol Bioeng 102:1251-1258.
    • (2009) Biotechnol Bioeng , vol.102 , pp. 1251-1258
    • Boado, R.J.1    Zhang, Y.2    Wang, Y.3    Pardridge, W.M.4
  • 3
    • 33846897981 scopus 로고    scopus 로고
    • Humanization of anti-human insulin receptor antibody for drug targeting across the human blood-brain barrier
    • DOI 10.1002/bit.21120
    • Boado RJ, Zhang Y, Zhang Y, and Pardridge WM (2007) Humanization of antihuman insulin receptor antibody for drug targeting across the human blood-brain barrier. Biotechnol Bioeng 96:381-391. (Pubitemid 46232272)
    • (2007) Biotechnology and Bioengineering , vol.96 , Issue.2 , pp. 381-391
    • Boado, R.J.1    Zhang, Y.2    Zhang, Y.3    Pardridge, W.M.4
  • 4
    • 0037204948 scopus 로고    scopus 로고
    • TNF-R1 signaling: A beautiful pathway
    • DOI 10.1126/science.1071924
    • Chen G and Goeddel DV (2002) TNF-R1 signaling: a beautiful pathway. Science 296:1634-1635. (Pubitemid 34579145)
    • (2002) Science , vol.296 , Issue.5573 , pp. 1634-1635
    • Chen, G.1    Goeddel, D.V.2
  • 7
    • 2542475349 scopus 로고    scopus 로고
    • Genetic ablation of tumor necrosis factor-alpha (TNF-alpha) and pharmacological inhibition of TNF-synthesis attenuates MPTP toxicity in mouse striatum
    • DOI 10.1111/j.1471-4159.2004.02399.x
    • Ferger B, Leng A, Mura A, Hengerer B, and Feldon J (2004) Genetic ablation of tumor necrosis factor-α (TNF-α) and pharmacological inhibition of TNF-synthesis attenuates MPTP toxicity in mouse striatum. J Neurochem 89:822-833. (Pubitemid 38684730)
    • (2004) Journal of Neurochemistry , vol.89 , Issue.4 , pp. 822-833
    • Ferger, B.1    Leng, A.2    Mura, A.3    Hengerer, B.4    Feldon, J.5
  • 8
    • 77956178352 scopus 로고    scopus 로고
    • Intravenous treatment of experimental Parkinson's disease in the mouse with an IgG-GDNF fusion protein that penetrates the blood-brain barrier
    • Fu A, Zhou QH, Hui EK, Lu JZ, Boado RJ, and Pardridge WM (2010) Intravenous treatment of experimental Parkinson's disease in the mouse with an IgG-GDNF fusion protein that penetrates the blood-brain barrier. Brain Res 1352:208-213.
    • (2010) Brain Res , vol.1352 , pp. 208-213
    • Fu, A.1    Zhou, Q.H.2    Hui, E.K.3    Lu, J.Z.4    Boado, R.J.5    Pardridge, W.M.6
  • 9
    • 34548316575 scopus 로고    scopus 로고
    • Deletion of tumor necrosis factor death receptor inhibits amyloid β generation and prevents learning and memory deficits in Alzheimer's mice
    • DOI 10.1083/jcb.200705042
    • He P, Zhong Z, Lindholm K, Berning L, Lee W, Lemere C, Staufenbiel M, Li R, and Shen Y (2007) Deletion of tumor necrosis factor death receptor inhibits amyloid beta generation and prevents learning and memory deficits in Alzheimer's mice. J Cell Biol 178:829-841. (Pubitemid 47347367)
    • (2007) Journal of Cell Biology , vol.178 , Issue.5 , pp. 829-841
    • He, P.1    Zhong, Z.2    Lindholm, K.3    Berning, L.4    Lee, W.5    Lemere, C.6    Staufenbiel, M.7    Li, R.8    Shen, Y.9
  • 11
    • 70349784159 scopus 로고    scopus 로고
    • Tumor necrosis factor receptor-IgG fusion protein for targeted-drug delivery across the human blood-brain barrier
    • Hui EK, Boado RJ, and Pardridge WM (2009) Tumor necrosis factor receptor-IgG fusion protein for targeted-drug delivery across the human blood-brain barrier. Mol Pharm 6:1536-1543.
    • (2009) Mol Pharm , vol.6 , pp. 1536-1543
    • Hui, E.K.1    Boado, R.J.2    Pardridge, W.M.3
  • 16
    • 33748702290 scopus 로고    scopus 로고
    • Blocking soluble tumor necrosis factor signaling with dominant-negative tumor necrosis factor inhibitor attenuates loss of dopaminergic neurons in models of Parkinson's disease
    • DOI 10.1523/JNEUROSCI.1504-06.2006
    • McCoy MK, Martinez TN, Ruhn KA, Szymkowski DE, Smith CG, Botterman BR, Tansey KE, and Tansey MG (2006) Blocking soluble tumor necrosis factor signaling with dominant-negative tumor necrosis factor inhibitor attenuates loss of dopaminergic neurons in models of Parkinson's disease. J Neurosci 26:9365-9375. (Pubitemid 44396849)
    • (2006) Journal of Neuroscience , vol.26 , Issue.37 , pp. 9365-9375
    • McCoy, M.K.1    Martinez, T.N.2    Ruhn, K.A.3    Szymkowski, D.E.4    Smith, C.G.5    Botterman, B.R.6    Tansey, K.E.7    Tansey, M.G.8
  • 17
    • 0035673169 scopus 로고    scopus 로고
    • Association of tumor necrosis factor receptor type II polymorphism 196R with systemic lupus erythematosus in the Japanese molecular and functional analysis
    • DOI 10.1002/1529-0131(200112)44:12<2819::AID-ART469>3.0.CO;2-2
    • Morita C, Horiuchi T, Tsukamoto H, Hatta N, Kikuchi Y, Arinobu Y, Otsuka T, Sawabe T, Harashima S, Nagasawa K, et al. (2001) Association of tumor necrosis factor receptor type II polymorphism 196R with systemic lupus erythematosus in the Japanese: molecular and functional analysis. Arthritis Rheum 44:2819-2827. (Pubitemid 34016201)
    • (2001) Arthritis and Rheumatism , vol.44 , Issue.12 , pp. 2819-2827
    • Morita, C.1    Horiuchi, T.2    Tsukamoto, H.3    Hatta, N.4    Kikuchi, Y.5    Arinobu, Y.6    Otsuka, T.7    Sawabe, T.8    Harashima, S.-I.9    Nagasawa, K.10    Niho, Y.11
  • 18
    • 77949375780 scopus 로고    scopus 로고
    • Biopharmaceutical drug targeting to the brain
    • Pardridge WM (2010) Biopharmaceutical drug targeting to the brain. J Drug Target 18:157-167.
    • (2010) J Drug Target , vol.18 , pp. 157-167
    • Pardridge, W.M.1
  • 19
    • 0029009048 scopus 로고
    • Human insulin receptor monoclonal antibody undergoes high affinity binding to human brain capillaries in vitro and rapid transcytosis through the blood-brain barrier in vivo in the primate
    • Pardridge WM, Kang YS, Buciak JL, and Yang J (1995) Human insulin receptor monoclonal antibody undergoes high affinity binding to human brain capillaries in vitro and rapid transcytosis through the blood-brain barrier in vivo in the primate. Pharm Res 12:807-816.
    • (1995) Pharm Res , vol.12 , pp. 807-816
    • Pardridge, W.M.1    Kang, Y.S.2    Buciak, J.L.3    Yang, J.4
  • 20
    • 0025827590 scopus 로고
    • A tumor necrosis factor (TNF) receptor-IgG heavy chain chimeric protein as a bivalent antagonist of TNF activity
    • Peppel K, Crawford D, and Beutler B (1991) A tumor necrosis factor (TNF) receptor-IgG heavy chain chimeric protein as a bivalent antagonist of TNF activity. J Exp Med 174:1483-1489.
    • (1991) J Exp Med , vol.174 , pp. 1483-1489
    • Peppel, K.1    Crawford, D.2    Beutler, B.3
  • 22
    • 0028810703 scopus 로고
    • Functional comparisons of different tumour necrosis factor receptor/IgG fusion proteins
    • Scallon BJ, Trinh H, Nedelman M, Brennan FM, Feldmann M, and Ghrayeb J (1995) Functional comparisons of different tumour necrosis factor receptor/IgG fusion proteins. Cytokine 7:759-770.
    • (1995) Cytokine , vol.7 , pp. 759-770
    • Scallon, B.J.1    Trinh, H.2    Nedelman, M.3    Brennan, F.M.4    Feldmann, M.5    Ghrayeb, J.6
  • 24
    • 34250682223 scopus 로고    scopus 로고
    • Enhanced Fc-dependent cellular cytotoxicity of Fc fusion proteins derived from TNF receptor II and LFA-3 by fucose removal from asn-linked oligosaccharides
    • DOI 10.1093/jb/mvj207
    • Shoji-Hosaka E, Kobayashi Y, Wakitani M, Uchida K, Niwa R, Nakamura K, and Shitara K (2006) Enhanced Fc-dependent cellular cytotoxicity of Fc fusion proteins derived from TNF receptor II and LFA-3 by fucose removal from Asn-linked oligosaccharides. J Biochem 140:777-783. (Pubitemid 46941006)
    • (2006) Journal of Biochemistry , vol.140 , Issue.6 , pp. 777-783
    • Shoji-Hosaka, E.1    Kobayashi, Y.2    Wakitani, M.3    Uchida, K.4    Niwa, R.5    Nakamura, K.6    Shitara, K.7
  • 25
    • 0036719568 scopus 로고    scopus 로고
    • Mice deficient in TNF receptors are protected against dopaminergic neurotoxicity: Implications for Parkinson's disease
    • Sriram K, Matheson JM, Benkovic SA, Miller DB, Luster MI, and O'Callaghan JP (2002) Mice deficient in TNF receptors are protected against dopaminergic neurotoxicity: implications for Parkinson's disease. FASEB J 16:1474-1476.
    • (2002) FASEB J , vol.16 , pp. 1474-1476
    • Sriram, K.1    Matheson, J.M.2    Benkovic, S.A.3    Miller, D.B.4    Luster, M.I.5    O'Callaghan, J.P.6
  • 26
    • 71749092275 scopus 로고    scopus 로고
    • The TNF superfamily in 2009: New pathways, new indications, and new drugs
    • Tansey MG and Szymkowski DE (2009) The TNF superfamily in 2009: new pathways, new indications, and new drugs. Drug Discov Today 14:1082-1088.
    • (2009) Drug Discov Today , vol.14 , pp. 1082-1088
    • Tansey, M.G.1    Szymkowski, D.E.2
  • 27
    • 33947323582 scopus 로고    scopus 로고
    • TNF-alpha knockout and minocycline treatment attenuates blood-brain barrier leakage in MPTP-treated mice
    • DOI 10.1016/j.nbd.2006.11.012, PII S096999610600307X
    • Zhao C, Ling Z, Newman MB, Bhatia A, and Carvey PM (2007) TNF-α knockout and minocycline treatment attenuates blood-brain barrier leakage in MPTP-treated mice. Neurobiol Dis 26:36-46. (Pubitemid 46437443)
    • (2007) Neurobiology of Disease , vol.26 , Issue.1 , pp. 36-46
    • Zhao, C.1    Ling, Z.2    Newman, M.B.3    Bhatia, A.4    Carvey, P.M.5
  • 29
    • 79959444718 scopus 로고    scopus 로고
    • Chronic dosing of mice with a transferrin receptor monoclonal antibody-glial-derived neurotrophic factor fusion protein
    • Zhou QH, Boado RJ, Hui EK, Lu JZ, and Pardridge WM (2011b) Chronic dosing of mice with a transferrin receptor monoclonal antibody-glial-derived neurotrophic factor fusion protein. Drug Metab Dispos 39:1149-1154.
    • (2011) Drug Metab Dispos , vol.39 , pp. 1149-1154
    • Zhou, Q.H.1    Boado, R.J.2    Hui, E.K.3    Lu, J.Z.4    Pardridge, W.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.