Enhanced immune response and protective efficacy of a Treponema pallidum Tp92 DNA vaccine vectored by chitosan nanoparticles and adjuvanted with IL-2

Human Vaccines

Volumn 7, Issue 10, 2011, Pages

  Zhao, Feijun ^a,b   Wu, Yimou ^b   Zhang, Xiaohong ^b   Yu, Jian ^b   Gu, Weiming ^c   Liu, Shuangquan ^a   Zeng, Tiebing ^b   Zhang, Yuejun ^b   Wang, Shiping ^a  

^a Central South University   (China)

^b UNIVERSITY OF SOUTH CHINA   (China)

^c Skin Diseases and STD Hospital   (China)

Author keywords

CS; IL 2; Membrane protein; Nucleic acid vaccine; Tp92; Treponema pallidum (Tp)

Indexed keywords

BACTERIAL VECTOR; BACTERIUM ANTIBODY; CHITOSAN; DNA VACCINE; GAMMA INTERFERON; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 2; NANOPARTICLE; TP92 ANTIBODY; TP92 ANTIGEN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BACTERIAL INFECTION; CELLULAR IMMUNITY; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG EFFICACY; DRUG FORMULATION; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNIZATION; INFECTION PREVENTION; LYMPHOCYTE PROLIFERATION; NONHUMAN; SKIN DEFECT; TREATMENT RESPONSE; TREPONEMA PALLIDUM; ULCER;

EID: 80054770356     PISSN: 15548600     EISSN: 15548619     Source Type: Journal    
DOI: 10.4161/hv.7.9     Document Type: Article

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