The TprK protein of Treponema pallidum is periplasmic and is not a target of opsonic antibody or protective immunity

Journal of Experimental Medicine

Volumn 193, Issue 9, 2001, Pages 1015-1026

  Hazlett, Karsten R O ^a   Sellati, Timothy J ^a,c   Nguyen, Tung T ^a   Cox, David L ^b   Clawson, Michael L ^a   Caimano, Melissa J ^a   Radolf, Justin D ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^b CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^c ALBANY MEDICAL COLLEGE   (United States)

Author keywords

Antigenic variation; Membrane protein; Opsonization; Spirochete; Vaccine

Indexed keywords

ANTIBODY; BACTERIAL PROTEIN; PROTEIN TPRK; PROTEINASE K; RECOMBINANT PROTEIN; SIGNAL PEPTIDE; TRITON X 114; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANTIGENIC VARIATION; ARTICLE; CELLULAR DISTRIBUTION; CYTOPLASM; ESCHERICHIA COLI; IMMUNIZATION; IMMUNOFLUORESCENCE; NONHUMAN; OPSONIZATION; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RABBIT; SYPHILIS; TREPONEMA PALLIDUM;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, BACTERIAL; BACTERIAL OUTER MEMBRANE PROTEINS; BASE SEQUENCE; CELL MEMBRANE; CODON, INITIATOR; DNA, BACTERIAL; ENDOPEPTIDASE K; GENES, BACTERIAL; MOLECULAR SEQUENCE DATA; PERIPLASM; PROTEIN BIOSYNTHESIS; RABBITS; SEQUENCE HOMOLOGY, AMINO ACID; SYPHILIS; TRANSCRIPTION, GENETIC; TREPONEMA PALLIDUM; VACCINATION; VARIATION (GENETICS);

EID: 0035821220     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.193.9.1015     Document Type: Article

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