Computer simulations of cell sorting due to differential adhesion

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  Zhang, Ying ^a   Thomas, Gilberto L ^b   Swat, Maciej ^c   Shirinifard, Abbas ^c   Glazier, James A ^c  

^a NATIONAL CANCER INSTITUTE   (United States)

^b FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^c INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CADHERIN;

ARTICLE; CELL ADHESION; CELL DENSITY; CELL INTERACTION; CELL MEMBRANE; CELL MOTILITY; CELL SELECTION; CELL SURFACE; CELLULAR DISTRIBUTION; CIS DIMER MODEL; COMPUTER MODEL; COMPUTER SIMULATION; CONTROLLED STUDY; GLAZIER GRANER HOGEWEG MODEL; INTRACELLULAR SIGNALING; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN EXPRESSION; SATURATION MODEL; TRANS HEMOPHILIC BOND MODEL; BIOLOGICAL MODEL; CELL MOTION; KINETICS; METABOLISM; THERMODYNAMICS;

CADHERINS; CELL ADHESION; CELL MEMBRANE; CELL MOVEMENT; COMPUTER SIMULATION; KINETICS; MODELS, BIOLOGICAL; THERMODYNAMICS;

EID: 80054761006     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0024999     Document Type: Article

References (55)

1. Radice GL, Rayburn H, Matsunami H, Knudsen KA, Takeichi K, et al. (1997) Developmental defects in mouse embryos lacking N-cadherin. Dev Bio 181: 64-78.
2. Price SR, de Marco Garcia NV, Ranscht B, Jessell TM, (2002) Regulation of motor neuron pool sorting by differential expression of type II cadherins. Cell 109: 205-216.
3. Gumbiner BM, (2005) Regulation of cadherin-mediated adhesion in morphogenesis. Nature Rev Mol Cell Bio 6: 622-634.
4. Xu X, Li WE, Huang GY, Meyer R, Chen T, et al. (2001) Modulation of mouse neural crest cell motility by N-cadherin and connexin 43 gap junctions. J Cell Bio 154: 217-230.
5. Linask KK, Ludwig C, Han MD, Liu X, Radice GL, et al. (1998) Ncadherin/catenin-mediated morphoregulation of somite formation. Dev Bio 202: 85-102.
6. Horikawa K, Radice GL, Takeichi M, Chisaka O, (1999) Adhesive subdivisions intrinsic to the epithelial somites. Dev Bio 215: 182-189.
7. Takeichi M, (1993) Cadherins in cancer: implications for invasion and metastasis. Curr Op Cell Bio 5: 806-811.
8. Berx G, Van Roy F, (2001) The E-cadherin/catenin complex: an important gatekeeper in breast cancer tumorigenesis and malignant progression. Breast Cancer Res 3: 289-293.
9. Bement WM, Forscher P, Mooseker MS, (1993) A novel cytoskeletal structure involved in purse string wound closure and cell polarity maintenance. J Cell Biol 121: 565-578.
10. Lorger M, Moelling K, (2006) Regulation of epithelial wound closure and intercellular adhesion by interaction of AF6 with actin cytoskeleton. J Cell Sci 119: 3385-3398.
11. Yajima H, Yoneitamura S, Watanabe N, Tamura K, Ide H, (1999) Role of N-cadherin in the sorting-out of mesenchymal cells and in the positional identity along the proximodistal axis of the chick limb bud. Dev Dyn 216: 274-284.
12. Bitzur S, Kam Z, Geiger B, (1994) Structure and distribution of N-cadherin in developing zebrafish embryos: morphogenetic effects of ectopic over-expression. Dev Dyn 201: 121-136.
13. Omi M, Anderson R, Muneoka K, (2002) Differential cell affinity and sorting of anterior and posterior cells during outgrowth of recombinant avian limb buds. Dev Biol 250: 292-304.
14. Godt D, Tepass U, (1998) Drosophila oocyte localization is mediated by differential cadherin-based adhesion. Nature 395: 387-391.
15. Von der Hardt S, Bakkers J, Inbal A, Carvalho L, Solnica-Krezel L, et al. (2007) The Bmp gradient of the zebrafish gastrula guides migrating lateral cells by regulating cell-cell adhesion. Curr Bio 17: 475-487.
16. Steinberg MS, (1963) Reconstruction of tissues by dissociated cells. Some morphogenetic tissue movements and the sorting out of embryonic cells may have a commonexplanation. Science 141: 401-408.
17. Steinberg MS, Wiseman LL, (1972) Do morphogenetic tissue rearrangements require active cell movements? The reversible inhibition of cell sorting and tissue spreading by cytochalasin B. J Cell Bio 55: 606-615.
18. Steinberg MS, Takeichi M, (1994) Experimental specification of cell sorting, tissue spreading, and specific spatial patterning by quantitative differences in cadherin expression. Proc Nat Ac Sc USA 91: 206-209.
19. Foty RA, Steinberg MS, (2005) The differential adhesion hypothesis: a direct evaluation. Dev Bio 278: 255-263.
20. Friedlander DR, Mege RM, Cunningham BA, Edelman GM, (1989) Cell sorting-out is modulated by both the specificity and amount of different cell adhesion molecules (CAMs) expressed on cell surfaces. Proc Nat Ac Sc USA 86: 7043-7047.
21. Niessen CM, Gumbiner BM, (2002) Cadherin-mediated cell sorting not determined by binding or adhesion specificity. J Cell Biol 156: 389-399.
22. Baumgartner W, Hinterdorfer P, Ness W, Raab A, Vestweber H, et al. (2000) Cadherin interaction probed by atomic force microscopy. Proc Nat Ac Sci USA 97: 4005-4010.
23. Chu YS, Thomas WA, Eder O, Pincet E, Perez E, et al. (2004) Force measurements in E-cadherin-mediated cell doublets reveal rapid adhesion strengthened by actin cytoskeleton remodeling through Rac and Cdc42. J Cell Biol 167: 1183-1194.
24. Panorchan P, Thompson MS, Davis KJ, Tseng Y, Konstantopoulos K, et al. (2006) Single-molecule analysis of cadherin-mediated cell-cell adhesion. J of Cell Sc 119: 66-74.
25. Prakasam AK, Maruthamuthu V, Leckband D, (2006) Similarities between heterophilic and homophilic cadherin adhesion. Proc Nat Ac Sc USA 103: 15434-15439.
26. Angres B, Barth A, Nelson WJ, (1996) Mechanism for transition from initial to stable cell-cell adhesion: kinetic analysis of E-cadherin-mediated adhesion using a quantitative adhesion assay. J Cell Biol 134: 549-557.
27. Adams CL, Nelson WJ, (1998) Cytomechanics of cadherin-mediated cell-cell adhesion. Curr Op Cell Biol 10: 572-577.
28. Adams CL, Chen YT, Smith SJ, Nelson WJ, (1998) Mechanisms of epithelial cell-cell adhesion and cell compaction revealed by high-resolution tracking of E-cadheringreen fluorescent protein. J Cell Biol 142: 1105-1119.
29. Behrens J, Birchmeier W, Goodman SL, Imhof BA, (1985) Dissociation of Madin-Darby canine kidney epithelial cells by the monoclonal antibody anti-arc-1: mechanistic aspects and identification of the antigen as a component related to uvomorulin. J Cell Biol 101: 1307-1315.
30. Halbleib JM, Nelson WJ, (2006) Cadherins in development: cell adhesion, sorting, and tissue morphogenesis. Genes & Development 20: 3199-3214.
31. Shapiro L, Fannon AM, Kwong PD, Thompson A, Lehmann MS, et al. (1995) Structural basis of cell-cell adhesion by cadherins. Nature 374: 327-337.
32. Sivasankar S, Brieher W, Lavrik N, Gumbiner BM, Leckband D, (1999) Direct molecular force measurements of multiple adhesive interactions between cadherin ectodomains. Proc Nat Ac Sc USA 96: 11820-11824.
33. Chappuis-Flament S, Wong E, Hicks LD, Kay CM, Gumbiner BM, (2001) Multiple cadherin extracellular repeats mediate homophilic binding and adhesion. J Cell Biol 154: 231-243.
34. Zhu B, Chappuis-Flament S, Wong E, Jensen IE, Gumbiner BM, et al. (2003) Functional analysis of the structural basis of homophilic cadherin adhesion. Biophys J 84: 4033-4042.
35. Pertz O, Bozic D, Koch AW, Fauser C, Brancaccio A, et al. (1999) A new crystal structure, Ca2+ dependence and mutational analysis reveal molecular details of E-cadherin homoassociation. EMBO J 18: 1738-1747.
36. Boggon TJ, Murray J, Chappuis-Flament S, Wong E, Gumbiner BM, et al. (2002) C-cadherin ectodomain structure and implications for cell adhesion mechanisms. Science 296: 1308-1313.
37. Chen CP, Posy S, Ben-Shaul A, Shapiro L, Honig BH, (2005) Specificity of cell-cell adhesion by classical cadherins: Critical role for low-affinity dimerization through beta-strand swapping. Proc Nat Ac Sc USA 102: 8531-8536.
38. Graner F, Glazier JA, (1992) Simulation of biological cell sorting using a twodimensional extended Potts model. Phys Rev Lett 69: 2013-2016.
39. Glazier JA, Graner F, (1993) Simulation of the differential adhesion driven rearrangement of biological cells. Phys Rev E 47: 2128-2154.
40. Glazier JA, Balter A, Poplawski NJ, (2007) pp. 79-106 Single-Cell-Based Models in Biology and Medicine, Birkhauser-Verlag, Basel, Switzerland, chapter Magnetization to morphogenesis: a brief history of the Glazier-Graner-Hogeweg model.
41. Mombach JC, Glazier JA, (1996) Single cell motion in aggregates of embryonic cells. Phys Rev Lett 76: 3032-3035.
42. Rieu JP, Upadhyaya A, Glazier JA, Ouchi NB, Sawada Y, (2000) Diffusion and deformations of single hydra cells in cellular aggregates. Biophys J 79: 1903-1914.
43. Zajac M, Jones GL, Glazier JA, (2000) Model of convergent extension in animal morphogenesis. Phys Rev Lett 85: 2022-2025.
44. Maree AF, Hogeweg P, (2001) How amoeboids self-organize into a fruiting body: multicellular coordination in Dictyostelium discoideum. Proc Nat Ac Sc USA 98: 3879-3883.
45. Zeng W, Thomas GL, Glazier JA, (2004) Non-Turing stripes and spots: a novel mechanism for biological cell clustering. Physica A 341: 482-494.
46. Dan D, Mueller C, Chen K, Glazier JA, (2005) Solving the advection-diffusion equations in biological contexts using the cellular Potts model. Phys Rev E 72: 041909.
47. Merks RHM, Glazier JA, (2005) A cell-centered approach to developmental biology. Physica A 352: 113-130.
48. Poplawski NJ, Swat M, Gens JS, Glazier JA, (2007) Adhesion between cells, diffusion of growth factors, and elasticity of the AER produce the paddle shape of the chick limb. Physica A 373C: 521-532.
49. Glazier JA, Zhang Y, Swat M, Zaitlen B, Schnell S, (2008) Coordinated action of N-CAM, N-cadherin, EphA4, and ephrinB2 translates genetic prepattern into structure during somitogenesis in chick. Curr Top Dev Biol 81: 205-247.
50. Metropolis N, Rosenbluth AW, Rosenbluth MN, Teller AH, Teller E, (1953) Equations of State Calculations by Fast Computing Machines. J ChemPhys 21: 1087-1092.
51. Armstrong PB, (1971) Light and electron microscope studies of cell sorting in combinations of chick embryo neural retina and retinal pigment epithelium. Wilhelm Roux' Archiv 168: 125-141.
52. Frenkel J, (1945) Viscous flow of crystalline bodies under the action of surface tension. J Phys 4: 385-431.
53. Beysens DA, Forgacs G, Glazier JA, (2000) Cell sorting is analogous to phase ordering in fluids. Proc Nat Ac Sc USA 97: 9467-9471.
54. Steinhaus H, (1956) Sur la division des corps materiels en parties. Bull Acad Polon Sci 4: 801-804.
55. Watanabe T, Sato Y, Saito D, Tadokoro R, Takahashi Y, (2009) EphrinB2 coordinates the formation of a morphological boundary and cell epithelialization during somite segmentation. Proc Natl Acad Sci U S A 106 (18): 7467-7472.