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Volumn 9, Issue 4, 2006, Pages 60-67

Prioritizing molecules for development based on physico-chemical characteristics

Author keywords

[No Author keywords available]

Indexed keywords

DRUG DEVELOPMENT; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STABILITY; PHYSICAL CHEMISTRY; REVIEW;

EID: 55749093285     PISSN: 10998012     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (9)

References (19)
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    • DiMasi, J.A.1    Hansen, R.W.2    Grabowski, H.G.3
  • 2
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    • Role of the development scientist in compound lead selection and optimization
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    • Venkatesh, S.1    Lipper, R.A.2
  • 3
    • 0023947965 scopus 로고    scopus 로고
    • Prentis, R.A., Lis, Y., Walker, S.R., Pharmaceutical innovation by the seven U.K.-owned pharmaceutical companies (1964-1985), British Journal of Clinical Pharmacology (1988) 25, 387-396.
    • Prentis, R.A., Lis, Y., Walker, S.R., Pharmaceutical innovation by the seven U.K.-owned pharmaceutical companies (1964-1985), British Journal of Clinical Pharmacology (1988) 25, 387-396.
  • 4
    • 0030886937 scopus 로고    scopus 로고
    • Kennedy, T., Managing the drug discovery/development interface, DDT (1997), 2 (10), 436-444.
    • Kennedy, T., Managing the drug discovery/development interface, DDT (1997), 2 (10), 436-444.
  • 6
    • 84888003088 scopus 로고    scopus 로고
    • Physicochemical properties and the discovery of orally active drugs: Technical and people issues, Molecular Informatics: Confronting Complexity
    • Martin G. Hicks & Carsten Kettner Eds, May 13th-16th, Bozen, Italy
    • Lipinski, C.A., Physicochemical properties and the discovery of orally active drugs: technical and people issues, Molecular Informatics: Confronting Complexity, Martin G. Hicks & Carsten Kettner (Eds.) Proceedings or the Beilstein-Institut Worsho, May 13th-16th 2002, Bozen, Italy (2003).
    • (2002) Proceedings or the Beilstein-Institut Worsho
    • Lipinski, C.A.1
  • 7
    • 19344374507 scopus 로고    scopus 로고
    • Improving Solubility in Lead Optimization
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    • (2004) American Pharmaceutical Review , vol.7 , pp. 30-32
    • Faller, B.1
  • 8
    • 0031024171 scopus 로고    scopus 로고
    • Experimental and computational apporaches to estimate solubility and permeability in drug discovery and development settings
    • Lipinski, C.A., Lombardo, F., Dominy, B.W., Feeney, P.J., Experimental and computational apporaches to estimate solubility and permeability in drug discovery and development settings, Advanced Drug Delivery Reviews (1997), 23, 3-25.
    • (1997) Advanced Drug Delivery Reviews , vol.23 , pp. 3-25
    • Lipinski, C.A.1    Lombardo, F.2    Dominy, B.W.3    Feeney, P.J.4
  • 9
    • 0343527392 scopus 로고    scopus 로고
    • Modern bioavailability, bioequivalence and biopharmaceutics classification system. New scientific approaches to international regulatory standards
    • Löbenberg, R., Amidon, G.L., Modern bioavailability, bioequivalence and biopharmaceutics classification system. New scientific approaches to international regulatory standards, European Journal of Pharmaceutics and Biopharmaceutics (2000) 50, 3-12.
    • (2000) European Journal of Pharmaceutics and Biopharmaceutics , vol.50 , pp. 3-12
    • Löbenberg, R.1    Amidon, G.L.2
  • 10
    • 1842689072 scopus 로고    scopus 로고
    • the 100 mg approach
    • Pharmaceutical evaluation of early development candidates
    • Balbach, S., Korn, C., Pharmaceutical evaluation of early development candidates "the 100 mg approach", International Journal of Pharmaceutics (2004) 275, 1-12.
    • (2004) International Journal of Pharmaceutics , vol.275 , pp. 1-12
    • Balbach, S.1    Korn, C.2
  • 12
    • 17644367503 scopus 로고    scopus 로고
    • Poorly water-soluble drugs for oral delivery - a challenge for pharmaceutical development
    • Rasenack, N., Müller, B.W., Poorly water-soluble drugs for oral delivery - a challenge for pharmaceutical development, Pharm. Ind. (2005) 67, 323-326.
    • (2005) Pharm. Ind , vol.67 , pp. 323-326
    • Rasenack, N.1    Müller, B.W.2
  • 13
    • 21044453591 scopus 로고    scopus 로고
    • Poorly water-soluble drugs for oral delivery - a challenge for pharmaceutical development
    • Rasenack, N., Müller, B.W., Poorly water-soluble drugs for oral delivery - a challenge for pharmaceutical development, Pharm. Ind. (2005) 67, 447-451.
    • (2005) Pharm. Ind , vol.67 , pp. 447-451
    • Rasenack, N.1    Müller, B.W.2
  • 14
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    • Poorly water-soluble drugs for oral delivery - a challenge for pharmaceutical development
    • Rasenack, N., Müller, B.W., Poorly water-soluble drugs for oral delivery - a challenge for pharmaceutical development, Pharm. Ind. (2005) 67, 583-591.
    • (2005) Pharm. Ind , vol.67 , pp. 583-591
    • Rasenack, N.1    Müller, B.W.2
  • 15
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    • Chaubal, M.V., Application of formulation technologies in lead candidate selection and optimization, DDT (2004) 9 (14), 603-609.
  • 18
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.