Synthesis of some substituted furan-2(5H)-ones and derived quinoxalinones as potential anti-microbial and anti-cancer agents

Medicinal Chemistry Research

Volumn 20, Issue 7, 2011, Pages 865-876

  El Tombary, Alaa A ^a   Abdel Ghany, Yasser S ^a   Belal, Ahmad S F ^a   Shams El Dine, Shams A ^a   Soliman, Farid S G ^a  

^a Alexandria University Faculty of Pharmacy   (Egypt)

Author keywords

3 (2 Aryl 1 halovinyl)quinoxalin 2(1H) ones; 3 Aryl 2 bromo 2 propenoic acids; 5 Aryl 4 halo 3 hydroxyfuran 2(5H) ones; Anti cancer and anti microbial properties

Indexed keywords

1,3 DIPHENYL 1H PYRAZOL 4 YL; 3 (2 ARYL 1 CHLORO) QUINOXALIN 2(1H) ONE; 3 (2 ARYL 1 IODOVINYL) QUINOXALIN 2(1H) ONE; 3 (4 BROMOPHENYL) 1 PHENYL 1H PYRAZOL 4 YL; 3 (4 METHOXYPHENYL) 1 PHENYL 1H PYRAZOL 4 YL; 3 ARYL 2 BROMO 2 PROPENOIC ACID; 3 BENZYLAMINOCARBONYLMETHYLOXY 4 BROMO 5 PHENYLFURAN 2(5H) ONE; 3,4 DIMETHOXYPHENYL; 3,5 DIMETHYL 1 PHENYL 1H PYRAZOL 4 YL; 4 BROMO 3 BROMOACETYLOXY 5 PHENYLFURAN 2(5H) ONE; 4 BROMO 3 HYDROXY 5 PHENYLFURAN 2(5H) ONE; 4 CHLORO 3 HYDROXY 5 (3,5 DIMETHYL 1 PHENYL 1H PYRAZOL 4 YL) FURAN 2(5H) ONE; 4 CHLOROPHENYL; 5 ARYL 3 HYDROXY 4 IODOFURAN 2(5H) ONE; 5 ARYL 4 CHLORO 3 HYDROXYFURAN 2(5H) ONE; ACRYLIC ACID DERIVATIVE; ANTIINFECTIVE AGENT; ANTINEOPLASTIC AGENT; CYCLIN B; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 5; CYCLIN DEPENDENT KINASE INHIBITOR; FURAN DERIVATIVE; FURANONE DERIVATIVE; GLYCOGEN SYNTHASE KINASE 3ALPHA; GLYCOGEN SYNTHASE KINASE 3BETA; PHENYL GROUP; PROTEIN P25; PYRAZOLE DERIVATIVE; QUINOXALINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; MINIMUM INHIBITORY CONCENTRATION; SPECTROSCOPY;

EID: 80054757626     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-010-9394-2     Document Type: Article

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