Prediction of the binding affinities of adenosine A2A receptor antagonists based on the heuristic method and support vector machine

Medicinal Chemistry Research

Volumn 20, Issue 8, 2011, Pages 1220-1228

  Lu, Peng ^a   Wei, Xia ^a   Zhang, Ruisheng ^a   Yuan, Yongna ^a   Gong, Zhiguo ^a  

^a LANZHOU UNIVERSITY   (China)

Author keywords

Adenosine A 2A receptor antagonists; Heuristic method; Molecular descriptor; QSAR; Support vector machine

Indexed keywords

ADENOSINE A2A RECEPTOR ANTAGONIST;

ARTICLE; BINDING AFFINITY; HEURISTIC METHOD; MACHINE LEARNING; PREDICTION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SUPPORT VECTOR MACHINE;

EID: 80054753953     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-010-9431-1     Document Type: Article

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