Refractory dispersion promotes conduction disturbance and arrhythmias in a Scn5a +/- mouse model

Pflugers Archiv European Journal of Physiology

Volumn 462, Issue 4, 2011, Pages 495-504

  Martin, Claire A ^a   Grace, Andrew A ^a   Huang, Christopher L H ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Action potential; Arrhythmia; Cardiac electrophysiology; Sodium channel; Ventricular fibrillation

Indexed keywords

FLECAINIDE; QUINIDINE;

ANIMAL TISSUE; ARRHYTHMOGENESIS; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENDOCARDIUM; EPICARDIUM; GENE; GENE EXPRESSION; HEART ARRHYTHMIA; HEART EXCITATION; HEART MUSCLE POTENTIAL; HEART MUSCLE REFRACTORY PERIOD; HEART REPOLARIZATION; HEART VENTRICULAR EFFECTIVE REFRACTORY PERIOD; ISOLATED HEART; MOUSE; NONHUMAN; PRIORITY JOURNAL; SCN5A GENE; STIMULUS RESPONSE; WILD TYPE;

ACTION POTENTIALS; ANIMALS; ANTI-ARRHYTHMIA AGENTS; ARRHYTHMIAS, CARDIAC; BRUGADA SYNDROME; ELECTRIC STIMULATION; FLECAINIDE; HEART; HEART VENTRICLES; ION CHANNEL GATING; MICE; QUINIDINE; REFRACTORY PERIOD, ELECTROPHYSIOLOGICAL; SODIUM CHANNELS;

EID: 80054740171     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-011-0989-3     Document Type: Article

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