Apoe genotype-function relationship: Evidence of -491 A/T promoter polymorphism modifying transcription control but not type 2 diabetes risk

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  Geng, Hua ^a   Law, Peggy P Y ^a   Ng, Maggie C Y ^b   Li, Ting ^a   Liang, Li Yun ^a   Ge, Tian Fang ^a   Wong, Kam Bo ^a   Liang, Chun ^c   Ma, Ronald C ^b   So, Wing Yee ^b   Chan, Juliana C N ^b   Ho, Yuan Yuan ^a,d  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^c HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

^d NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; APOLIPOPROTEIN E; COMPLEMENTARY DNA; SMALL INTERFERING RNA; ATF4 PROTEIN, HUMAN; GLUCOSE;

APOE GENE; ARTICLE; CASE CONTROL STUDY; CHINESE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA LIBRARY; ENDOPLASMIC RETICULUM STRESS; GEL MOBILITY SHIFT ASSAY; GENE; GENE EXPRESSION; GENE FUNCTION; GENE OVEREXPRESSION; GENE REPRESSION; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; GENOTYPE; HAPLOTYPE; HONG KONG; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; NON INSULIN DEPENDENT DIABETES MELLITUS; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSCRIPTION REGULATION; ADULT; CELL STRAIN HEK293; FEMALE; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION; GENETICS; HOMEOSTASIS; LIPID METABOLISM; MALE; METABOLISM;

ACTIVATING TRANSCRIPTION FACTOR 4; ADULT; APOLIPOPROTEINS E; DIABETES MELLITUS, TYPE 2; ENDOPLASMIC RETICULUM STRESS; FEMALE; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GLUCOSE; HEK293 CELLS; HOMEOSTASIS; HUMANS; LIPID METABOLISM; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; TRANSCRIPTION, GENETIC;

EID: 80054719821     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0024669     Document Type: Article

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