Plasma levels of apolipoprotein E and risk of stroke in old age

Annals of the New York Academy of Sciences

Volumn 1100, Issue , 2007, Pages 140-147

  Van Vliet, Peter ^a   Mooijaart, Simon P ^a   De Craen, Anton J M ^a   Rensen, Patrick C N ^a,b   Van Heemst, Diana ^a   Westendorp, Rudi G J ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b TNO   (Netherlands)

Author keywords

Atherosclerosis; Elderly; Plasma apolipoprotein E levels; Stroke

Indexed keywords

APOLIPOPROTEIN E; LIPID;

AGED; ALLELE; BLOOD CHEMISTRY; BLOOD SAMPLING; CARDIOVASCULAR RISK; CONFERENCE PAPER; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; FOLLOW UP; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOTE; HUMAN; INCIDENCE; INTERVIEW; LIPID BLOOD LEVEL; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PHYSICIAN; POPULATION RESEARCH; PROSPECTIVE STUDY; RISK ASSESSMENT; SENESCENCE; STROKE; ARTICLE; ATHEROSCLEROSIS; BLOOD; CEREBROVASCULAR ACCIDENT; CEREBROVASCULAR DISEASE; GENETIC PREDISPOSITION; GENETICS; ISCHEMIA; PATHOLOGY; RISK; RISK FACTOR;

AGED; AGED, 80 AND OVER; ALLELES; APOLIPOPROTEINS E; ATHEROSCLEROSIS; CEREBROVASCULAR ACCIDENT; CEREBROVASCULAR DISORDERS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; ISCHEMIA; MALE; RISK; RISK FACTORS;

EID: 34249660446     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1395.012     Document Type: Conference Paper

References (16)

1. EICHNER, J.E., S.T. DUNN, G. PERVEEN, et al. 2002. Apolipoprotein E polymorphism and cardiovascular disease: a HuGE review. Am. J. Epidemiol. 155: 487-495.
2. STENGARD, J.H., K.M. WEISS & C.F. SING. 1998. An ecological study of association between coronary heart disease mortality rates in men and the relative frequencies of common allelic variations in the gene coding for apolipoprotein. E. Hum. Genet. 103: 234-241.
3. WANG, X.L., R.M. MCCREDIE & D.E. WILCKEN. 1995. Polymorphisms of the apolipoprotein E gene and severity of coronary artery disease defined by angiography. Arterioscler. Thromb. Vasc. Biol. 15: 1030-1034.
4. MCCARRON, M.O., D. DELONG & M.J. ALBERTS. 1999. APOE genotype as a risk factor for ischemic cerebrovascular disease: a meta-analysis. Neurology 53: 1308-1311.
5. MARGAGLIONE, M., D. SERIPA, C. GRAVINA, et al. 1998. Prevalence of apolipoprotein E alleles in healthy subjects and survivors of ischemic stroke: an Italian case-control study. Stroke 29: 399-403.
6. PEZZINI, A., M. GRASSI, E. DEL ZOTTO, et al. 2004. Synergistic effect of apolipoprotein E polymorphisms and cigarette smoking on risk of ischemic stroke in young adults. Stroke 35: 438-442.
7. SUDLOW, C., N.A. MARTINEZ GONZALEZ, J. KIM & C. CLARK. 2006. Does apolipoprotein E genotype influence the risk of ischemic stroke, intracerebral hemorrhage, or subarachnoid hemorrhage? Systematic reviewand meta-analyses of 31 studies among 5961 cases and 17,965 controls. Stroke 37: 364-370.
8. MOOIJAART, S.P., J.F. BERBEE, D. VAN HEEMST, et al. 2005. ApoE plasma levels and risk of cardiovascular mortality in old age. PLoS Med. 3: e176.
9. BOOTSMA VAN DER WIEL, A., E. VAN EXEL, A.J. DE CRAEN, et al. 2002. A high response is not essential to prevent selection bias: results from the Leiden 85-plus study. J. Clin. Epidemiol. 55: 1119-1125.
10. KRONZON, I. & P.A. TUNICK. 2006. Aortic atherosclerotic disease and stroke. Circulation 114: 63-75.
11. HANSSON, G.K. 2005. Inflammation, atherosclerosis, and coronary artery disease. N. Engl. J. Med. 352: 1685-1695.
12. LARKIN, L., L.M. KHACHIGIAN & W. JESSUP. 2000. Regulation of apolipoprotein E production in macrophages [Review]. Int. J. Mol. Med. 6: 253-258.
13. BEEKMAN, M., B.T. HEIJMANS, N.G. MARTIN, et al. 2002. Heritabilities of apolipoprotein and lipid levels in three countries. Twin Res. 5: 87-97.
14. CARMENA, R., P. DURIEZ & J.C. FRUCHART. 2004. Atherogenic lipoprotein particles in atherosclerosis. Circulation 109: III2-III7.
15. VAN DEN, E.P., S. GARG, L. LEON, et al. 2005. Apolipoprotein-mediated pathways of lipid antigen presentation. Nature 437: 906-910.
16. LIBBY, P., P.M. RIDKER & A. MASERI. 2002. Inflammation and atherosclerosis. Circulation 105: 1135-1143.