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Volumn 6, Issue 10, 2011, Pages

Viscum album exerts anti-inflammatory effect by selectively inhibiting cytokine-induced expression of cyclooxygenase-2

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; INTERLEUKIN 1BETA; PROSTAGLANDIN E2; VISCUM ALBUM EXTRACT; PLANT EXTRACT;

EID: 80054718264     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0026312     Document Type: Article
Times cited : (55)

References (75)
  • 1
    • 0020433058 scopus 로고
    • Isolation and characterization of viscumin, a toxic lectin from Viscum album L. (mistletoe)
    • Olsnes S, Stirpe F, Sandvig K, Pihl A, (1982) Isolation and characterization of viscumin, a toxic lectin from Viscum album L. (mistletoe). J Biol Chem 257: 13263-13270.
    • (1982) J Biol Chem , vol.257 , pp. 13263-13270
    • Olsnes, S.1    Stirpe, F.2    Sandvig, K.3    Pihl, A.4
  • 2
    • 0022972025 scopus 로고
    • Recent studies on the anticancer activities of mistletoe (Viscum album) and its alkaloids
    • Khwaja TA, Dias CB, Pentecost S, (1986) Recent studies on the anticancer activities of mistletoe (Viscum album) and its alkaloids. Oncology 43 (Suppl 1): 42-50.
    • (1986) Oncology , vol.43 , Issue.SUPPL. 1 , pp. 42-50
    • Khwaja, T.A.1    Dias, C.B.2    Pentecost, S.3
  • 3
    • 0019566398 scopus 로고
    • Isolation and properties of three lectins from mistletoe (Viscum album L.)
    • Franz H, Ziska P, Kindt A, (1981) Isolation and properties of three lectins from mistletoe (Viscum album L.). Biochem J 195: 481-484.
    • (1981) Biochem J , vol.195 , pp. 481-484
    • Franz, H.1    Ziska, P.2    Kindt, A.3
  • 4
    • 33748652065 scopus 로고    scopus 로고
    • Viscotoxins, mistletoe lectins and their isoforms in mistletoe (Viscum album L.) extracts Iscador
    • Urech K, Schaller G, Jaggy C, (2006) Viscotoxins, mistletoe lectins and their isoforms in mistletoe (Viscum album L.) extracts Iscador. Arzneimittelforschung 56: 428-434.
    • (2006) Arzneimittelforschung , vol.56 , pp. 428-434
    • Urech, K.1    Schaller, G.2    Jaggy, C.3
  • 5
    • 0032485794 scopus 로고    scopus 로고
    • Unconventional therapies for cancer: 3. Iscador. Task Force on Alternative Therapies of the Canadian Breast Cancer Research Initiative
    • Kaegi E, (1998) Unconventional therapies for cancer: 3. Iscador. Task Force on Alternative Therapies of the Canadian Breast Cancer Research Initiative. CMAJ 158: 1157-1159.
    • (1998) CMAJ , vol.158 , pp. 1157-1159
    • Kaegi, E.1
  • 6
    • 4344630940 scopus 로고    scopus 로고
    • Efficacy and safety of long-term complementary treatment with standardized European mistletoe extract (Viscum album L.) in addition to the conventional adjuvant oncologic therapy in patients with primary non-metastasized mammary carcinoma. Results of a multi-center, comparative, epidemiological cohort study in Germany and Switzerland
    • Bock PR, Friedel WE, Hanisch J, Karasmann M, Schneider B, (2004) [Efficacy and safety of long-term complementary treatment with standardized European mistletoe extract (Viscum album L.) in addition to the conventional adjuvant oncologic therapy in patients with primary non-metastasized mammary carcinoma. Results of a multi-center, comparative, epidemiological cohort study in Germany and Switzerland]. Arzneimittelforschung 54: 456-466.
    • (2004) Arzneimittelforschung , vol.54 , pp. 456-466
    • Bock, P.R.1    Friedel, W.E.2    Hanisch, J.3    Karasmann, M.4    Schneider, B.5
  • 7
    • 16444383200 scopus 로고    scopus 로고
    • Influence of complementary Viscum album (Iscador) administration on microcirculation and immune system of ear, nose and throat carcinoma patients treated with radiation and chemotherapy
    • Klopp R, Schmidt W, Werner E, Werner M, Niemer W, et al. (2005) Influence of complementary Viscum album (Iscador) administration on microcirculation and immune system of ear, nose and throat carcinoma patients treated with radiation and chemotherapy. Anticancer Res 25: 601-610.
    • (2005) Anticancer Res , vol.25 , pp. 601-610
    • Klopp, R.1    Schmidt, W.2    Werner, E.3    Werner, M.4    Niemer, W.5
  • 8
    • 12944320296 scopus 로고    scopus 로고
    • Safety and efficacy of the long-term adjuvant treatment of primary intermediate- to high-risk malignant melanoma (UICC/AJCC stage II and III) with a standardized fermented European mistletoe (Viscum album L.) extract. Results from a multicenter, comparative, epidemiological cohort study in Germany and Switzerland
    • Augustin M, Bock PR, Hanisch J, Karasmann M, Schneider B, (2005) Safety and efficacy of the long-term adjuvant treatment of primary intermediate- to high-risk malignant melanoma (UICC/AJCC stage II and III) with a standardized fermented European mistletoe (Viscum album L.) extract. Results from a multicenter, comparative, epidemiological cohort study in Germany and Switzerland. Arzneimittelforschung 55: 38-49.
    • (2005) Arzneimittelforschung , vol.55 , pp. 38-49
    • Augustin, M.1    Bock, P.R.2    Hanisch, J.3    Karasmann, M.4    Schneider, B.5
  • 9
    • 28444445184 scopus 로고    scopus 로고
    • Prevention of surgery-induced suppression of granulocyte function by intravenous application of a fermented extract from Viscum album L. in breast cancer patients
    • Bussing A, Bischof M, Hatzmann W, Bartsch F, Soto-Vera D, et al. (2005) Prevention of surgery-induced suppression of granulocyte function by intravenous application of a fermented extract from Viscum album L. in breast cancer patients. Anticancer Res 25: 4753-4757.
    • (2005) Anticancer Res , vol.25 , pp. 4753-4757
    • Bussing, A.1    Bischof, M.2    Hatzmann, W.3    Bartsch, F.4    Soto-Vera, D.5
  • 10
    • 77954199043 scopus 로고    scopus 로고
    • Review article: Influence of Viscum album L (European mistletoe) extracts on quality of life in cancer patients: a systematic review of controlled clinical studies
    • Kienle GS, Kiene H, (2010) Review article: Influence of Viscum album L (European mistletoe) extracts on quality of life in cancer patients: a systematic review of controlled clinical studies. Integr Cancer Ther 9: 142-157.
    • (2010) Integr Cancer Ther , vol.9 , pp. 142-157
    • Kienle, G.S.1    Kiene, H.2
  • 11
    • 33646468844 scopus 로고    scopus 로고
    • Neurophysiological effects of mistletoe (Viscum album L.) on isolated rat intestines
    • Radenkovic M, Ivetic V, Popovic M, Mimica-Dukic N, Veljkovic S, (2006) Neurophysiological effects of mistletoe (Viscum album L.) on isolated rat intestines. Phytother Res 20: 374-377.
    • (2006) Phytother Res , vol.20 , pp. 374-377
    • Radenkovic, M.1    Ivetic, V.2    Popovic, M.3    Mimica-Dukic, N.4    Veljkovic, S.5
  • 12
    • 29744450764 scopus 로고    scopus 로고
    • Exploratory study on the effects of treatment with two mistletoe preparations on chronic hepatitis C
    • Tusenius KJ, Spoek AM, van Hattum J, (2005) Exploratory study on the effects of treatment with two mistletoe preparations on chronic hepatitis C. Arzneimittelforschung 55: 749-753.
    • (2005) Arzneimittelforschung , vol.55 , pp. 749-753
    • Tusenius, K.J.1    Spoek, A.M.2    van Hattum, J.3
  • 13
    • 14744270690 scopus 로고    scopus 로고
    • Vasodilator activity of the aqueous extract of Viscum album
    • Tenorio FA, del Valle L, Gonzalez A, Pastelin G, (2005) Vasodilator activity of the aqueous extract of Viscum album. Fitoterapia 76: 204-209.
    • (2005) Fitoterapia , vol.76 , pp. 204-209
    • Tenorio, F.A.1    del Valle, L.2    Gonzalez, A.3    Pastelin, G.4
  • 14
    • 0038476585 scopus 로고    scopus 로고
    • Antiviral potency of mistletoe (Viscum album ssp. album) extracts against human parainfluenza virus type 2 in Vero cells
    • Karagoz A, Onay E, Arda N, Kuru A, (2003) Antiviral potency of mistletoe (Viscum album ssp. album) extracts against human parainfluenza virus type 2 in Vero cells. Phytother Res 17: 560-562.
    • (2003) Phytother Res , vol.17 , pp. 560-562
    • Karagoz, A.1    Onay, E.2    Arda, N.3    Kuru, A.4
  • 16
    • 78349255316 scopus 로고    scopus 로고
    • Treatment of clinically diagnosed equine sarcoid with a mistletoe extract (Viscum album austriacus)
    • Christen-Clottu O, Klocke P, Burger D, Straub R, Gerber V, (2010) Treatment of clinically diagnosed equine sarcoid with a mistletoe extract (Viscum album austriacus). J Vet Intern Med 24: 1483-1489.
    • (2010) J Vet Intern Med , vol.24 , pp. 1483-1489
    • Christen-Clottu, O.1    Klocke, P.2    Burger, D.3    Straub, R.4    Gerber, V.5
  • 17
    • 0344628679 scopus 로고    scopus 로고
    • Apoptosis-inducing properties of Viscum album L. extracts from different host trees, correlate with their content of toxic mistletoe lectins
    • Bussing A, Schietzel M, (1999) Apoptosis-inducing properties of Viscum album L. extracts from different host trees, correlate with their content of toxic mistletoe lectins. Anticancer Res 19: 23-28.
    • (1999) Anticancer Res , vol.19 , pp. 23-28
    • Bussing, A.1    Schietzel, M.2
  • 18
    • 0343962160 scopus 로고    scopus 로고
    • Toxic proteins from European mistletoe (Viscum album L.): increase of intracellular IL-4 but decrease of IFN-gamma in apoptotic cells
    • Stein GM, Pfuller U, Schietzel M, Bussing A, (2000) Toxic proteins from European mistletoe (Viscum album L.): increase of intracellular IL-4 but decrease of IFN-gamma in apoptotic cells. Anticancer Res 20: 1673-1678.
    • (2000) Anticancer Res , vol.20 , pp. 1673-1678
    • Stein, G.M.1    Pfuller, U.2    Schietzel, M.3    Bussing, A.4
  • 19
    • 0033790303 scopus 로고    scopus 로고
    • Intracellular expression of IL-4 and inhibition of IFN-gamma by extracts from European mistletoe is related to induction of apoptosis
    • Stein GM, Pfuller U, Schietzel M, Bussing A, (2000) Intracellular expression of IL-4 and inhibition of IFN-gamma by extracts from European mistletoe is related to induction of apoptosis. Anticancer Res 20: 2987-2994.
    • (2000) Anticancer Res , vol.20 , pp. 2987-2994
    • Stein, G.M.1    Pfuller, U.2    Schietzel, M.3    Bussing, A.4
  • 20
    • 0036821227 scopus 로고    scopus 로고
    • Induction of apoptosis of endothelial cells by Viscum album: a role for anti-tumoral properties of mistletoe lectins
    • Duong Van Huyen JP, Bayry J, Delignat S, Gaston AT, Michel O, et al. (2002) Induction of apoptosis of endothelial cells by Viscum album: a role for anti-tumoral properties of mistletoe lectins. Mol Med 8: 600-606.
    • (2002) Mol Med , vol.8 , pp. 600-606
    • Duong van Huyen, J.P.1    Bayry, J.2    Delignat, S.3    Gaston, A.T.4    Michel, O.5
  • 21
    • 0346753573 scopus 로고    scopus 로고
    • Comparative study of the sensitivity of lymphoblastoid and transformed monocytic cell lines to the cytotoxic effects of Viscum album extracts of different origin
    • Duong Van Huyen JP, Delignat S, Kazatchkine MD, Kaveri SV, (2003) Comparative study of the sensitivity of lymphoblastoid and transformed monocytic cell lines to the cytotoxic effects of Viscum album extracts of different origin. Chemotherapy 49: 298-302.
    • (2003) Chemotherapy , vol.49 , pp. 298-302
    • Duong van Huyen, J.P.1    Delignat, S.2    Kazatchkine, M.D.3    Kaveri, S.V.4
  • 22
    • 33749257279 scopus 로고    scopus 로고
    • Interleukin-12 is associated with the in vivo anti-tumor effect of mistletoe extracts in B16 mouse melanoma
    • Duong Van Huyen JP, Delignat S, Bayry J, Kazatchkine MD, Bruneval P, et al. (2006) Interleukin-12 is associated with the in vivo anti-tumor effect of mistletoe extracts in B16 mouse melanoma. Cancer Lett 243: 32-37.
    • (2006) Cancer Lett , vol.243 , pp. 32-37
    • Duong van Huyen, J.P.1    Delignat, S.2    Bayry, J.3    Kazatchkine, M.D.4    Bruneval, P.5
  • 23
    • 33745927709 scopus 로고    scopus 로고
    • Immunologic effector mechanisms of a standardized mistletoe extract on the function of human monocytes and lymphocytes in vitro, ex vivo, and in vivo
    • Heinzerling L, von Baehr V, Liebenthal C, von Baehr R, Volk HD, (2006) Immunologic effector mechanisms of a standardized mistletoe extract on the function of human monocytes and lymphocytes in vitro, ex vivo, and in vivo. J Clin Immunol 26: 347-359.
    • (2006) J Clin Immunol , vol.26 , pp. 347-359
    • Heinzerling, L.1    von Baehr, V.2    Liebenthal, C.3    von Baehr, R.4    Volk, H.D.5
  • 24
    • 0036875802 scopus 로고    scopus 로고
    • Stimulation of the maturation of dendritic cells in vitro by a fermented mistletoe extract
    • Stein GM, Bussing A, Schietzel M, (2002) Stimulation of the maturation of dendritic cells in vitro by a fermented mistletoe extract. Anticancer Res 22: 4215-4219.
    • (2002) Anticancer Res , vol.22 , pp. 4215-4219
    • Stein, G.M.1    Bussing, A.2    Schietzel, M.3
  • 25
    • 0029548382 scopus 로고
    • A plant lectin derived from Viscum album induces cytokine gene expression and protein production in cultures of human peripheral blood mononuclear cells
    • Hostanska K, Hajto T, Spagnoli GC, Fischer J, Lentzen H, et al. (1995) A plant lectin derived from Viscum album induces cytokine gene expression and protein production in cultures of human peripheral blood mononuclear cells. Nat Immun 14: 295-304.
    • (1995) Nat Immun , vol.14 , pp. 295-304
    • Hostanska, K.1    Hajto, T.2    Spagnoli, G.C.3    Fischer, J.4    Lentzen, H.5
  • 26
    • 47349093062 scopus 로고    scopus 로고
    • Induction of maturation and activation of human dendritic cells: a mechanism underlying the beneficial effect of Viscum album as complimentary therapy in cancer
    • Elluru SR, Duong van Huyen JP, Delignat S, Kazatchkine MD, Friboulet A, et al. (2008) Induction of maturation and activation of human dendritic cells: a mechanism underlying the beneficial effect of Viscum album as complimentary therapy in cancer. BMC Cancer 8: 161.
    • (2008) BMC Cancer , vol.8 , pp. 161
    • Elluru, S.R.1    Duong van Huyen, J.P.2    Delignat, S.3    Kazatchkine, M.D.4    Friboulet, A.5
  • 27
    • 0035743286 scopus 로고    scopus 로고
    • Variable sensitivity of lymphoblastoid cells to apoptosis induced by Viscum album Qu FrF, a therapeutic preparation of mistletoe lectin
    • Duong Van Huyen JP, Sooryanarayana, Delignat S, Bloch MF, Kazatchkine MD, et al. (2001) Variable sensitivity of lymphoblastoid cells to apoptosis induced by Viscum album Qu FrF, a therapeutic preparation of mistletoe lectin. Chemotherapy 47: 366-376.
    • (2001) Chemotherapy , vol.47 , pp. 366-376
    • Duong van Huyen, J.P.1    Sooryanarayana2    Delignat, S.3    Bloch, M.F.4    Kazatchkine, M.D.5
  • 28
    • 0035069113 scopus 로고    scopus 로고
    • Cellular and humoral adjuvant activity of lectins isolated from Korean mistletoe (Viscum album colaratum)
    • Yoon TJ, Yoo YC, Kang TB, Her E, Kim SH, et al. (2001) Cellular and humoral adjuvant activity of lectins isolated from Korean mistletoe (Viscum album colaratum). Int Immunopharmacol 1: 881-889.
    • (2001) Int Immunopharmacol , vol.1 , pp. 881-889
    • Yoon, T.J.1    Yoo, Y.C.2    Kang, T.B.3    Her, E.4    Kim, S.H.5
  • 29
    • 61449189674 scopus 로고    scopus 로고
    • Immunological response to mistletoe (Viscum album L.) in cancer patients: a four-case series
    • Gardin NE, (2009) Immunological response to mistletoe (Viscum album L.) in cancer patients: a four-case series. Phytother Res 23: 407-411.
    • (2009) Phytother Res , vol.23 , pp. 407-411
    • Gardin, N.E.1
  • 30
    • 0042911713 scopus 로고    scopus 로고
    • Influence of mistletoe (Viscum album) extracts on phagocytosis/burst activity of human phagocytes
    • Frank U, Engels I, Wagner A, Lacour M, Daschner FD, (2003) Influence of mistletoe (Viscum album) extracts on phagocytosis/burst activity of human phagocytes. Eur J Clin Microbiol Infect Dis 22: 501-503.
    • (2003) Eur J Clin Microbiol Infect Dis , vol.22 , pp. 501-503
    • Frank, U.1    Engels, I.2    Wagner, A.3    Lacour, M.4    Daschner, F.D.5
  • 31
    • 47949099098 scopus 로고    scopus 로고
    • Origin and physiological roles of inflammation
    • Medzhitov R, (2008) Origin and physiological roles of inflammation. Nature 454: 428-435.
    • (2008) Nature , vol.454 , pp. 428-435
    • Medzhitov, R.1
  • 33
    • 77950345093 scopus 로고    scopus 로고
    • Inflammation 2010: new adventures of an old flame
    • Medzhitov R, (2010) Inflammation 2010: new adventures of an old flame. Cell 140: 771-776.
    • (2010) Cell , vol.140 , pp. 771-776
    • Medzhitov, R.1
  • 34
    • 76649142736 scopus 로고    scopus 로고
    • Immunology: TL1A in the inflammatory network in autoimmune diseases
    • Bayry J, (2010) Immunology: TL1A in the inflammatory network in autoimmune diseases. Nat Rev Rheumatol 6: 67-68.
    • (2010) Nat Rev Rheumatol , vol.6 , pp. 67-68
    • Bayry, J.1
  • 35
    • 39649083371 scopus 로고    scopus 로고
    • Inflammatory mechanisms: the molecular basis of inflammation and disease
    • Libby P, (2007) Inflammatory mechanisms: the molecular basis of inflammation and disease. Nutr Rev 65: S140-146.
    • (2007) Nutr Rev , vol.65
    • Libby, P.1
  • 37
    • 77956520680 scopus 로고    scopus 로고
    • Basophils and nephritis in lupus
    • Kaveri SV, Mouthon L, Bayry J, (2010) Basophils and nephritis in lupus. N Engl J Med 363: 1080-1082.
    • (2010) N Engl J Med , vol.363 , pp. 1080-1082
    • Kaveri, S.V.1    Mouthon, L.2    Bayry, J.3
  • 38
    • 78049296549 scopus 로고    scopus 로고
    • Neutralisation of interleukin-13 in mice prevents airway pathology caused by chronic exposure to house dust mite
    • Tomlinson KL, Davies GC, Sutton DJ, Palframan RT, (2010) Neutralisation of interleukin-13 in mice prevents airway pathology caused by chronic exposure to house dust mite. PLoS One 5: e13136.
    • (2010) PLoS One , vol.5
    • Tomlinson, K.L.1    Davies, G.C.2    Sutton, D.J.3    Palframan, R.T.4
  • 39
    • 34447250604 scopus 로고    scopus 로고
    • Rescuing CD4+CD25+ regulatory T-cell functions in rheumatoid arthritis by cytokine-targeted monoclonal antibody therapy
    • Bayry J, Siberil S, Triebel F, Tough DF, Kaveri SV, (2007) Rescuing CD4+CD25+ regulatory T-cell functions in rheumatoid arthritis by cytokine-targeted monoclonal antibody therapy. Drug Discov Today 12: 548-552.
    • (2007) Drug Discov Today , vol.12 , pp. 548-552
    • Bayry, J.1    Siberil, S.2    Triebel, F.3    Tough, D.F.4    Kaveri, S.V.5
  • 40
    • 78649891437 scopus 로고    scopus 로고
    • In vitro and in vivo anti-inflammatory activity of 17-O-acetylacuminolide through the inhibition of cytokines, NF-kappaB translocation and IKKbeta activity
    • Achoui M, Appleton D, Abdulla MA, Awang K, Mohd MA, et al. (2010) In vitro and in vivo anti-inflammatory activity of 17-O-acetylacuminolide through the inhibition of cytokines, NF-kappaB translocation and IKKbeta activity. PLoS One 5: e15105.
    • (2010) PLoS One , vol.5
    • Achoui, M.1    Appleton, D.2    Abdulla, M.A.3    Awang, K.4    Mohd, M.A.5
  • 41
    • 65649133976 scopus 로고    scopus 로고
    • Surveillance of antigen-presenting cells by CD4+ CD25+ regulatory T cells in autoimmunity: immunopathogenesis and therapeutic implications
    • Andre S, Tough DF, Lacroix-Desmazes S, Kaveri SV, Bayry J, (2009) Surveillance of antigen-presenting cells by CD4+ CD25+ regulatory T cells in autoimmunity: immunopathogenesis and therapeutic implications. Am J Pathol 174: 1575-1587.
    • (2009) Am J Pathol , vol.174 , pp. 1575-1587
    • Andre, S.1    Tough, D.F.2    Lacroix-Desmazes, S.3    Kaveri, S.V.4    Bayry, J.5
  • 42
    • 78650770176 scopus 로고    scopus 로고
    • Induction of heme oxygenase-1 can halt and even reverse renal tubule-interstitial fibrosis
    • Correa-Costa M, Semedo P, Monteiro AP, Silva RC, Pereira RL, et al. (2010) Induction of heme oxygenase-1 can halt and even reverse renal tubule-interstitial fibrosis. PLoS One 5: e14298.
    • (2010) PLoS One , vol.5
    • Correa-Costa, M.1    Semedo, P.2    Monteiro, A.P.3    Silva, R.C.4    Pereira, R.L.5
  • 43
    • 67650376152 scopus 로고    scopus 로고
    • Autoimmunity: CTLA-4: a key protein in autoimmunity
    • Bayry J, (2009) Autoimmunity: CTLA-4: a key protein in autoimmunity. Nat Rev Rheumatol 5: 244-245.
    • (2009) Nat Rev Rheumatol , vol.5 , pp. 244-245
    • Bayry, J.1
  • 44
    • 78650763375 scopus 로고    scopus 로고
    • Angiopoietin-1 treatment reduces inflammation but does not prevent ventilator-induced lung injury
    • Hegeman MA, Hennus MP, van Meurs M, Cobelens PM, Kavelaars A, et al. (2010) Angiopoietin-1 treatment reduces inflammation but does not prevent ventilator-induced lung injury. PLoS One 5: e15653.
    • (2010) PLoS One , vol.5
    • Hegeman, M.A.1    Hennus, M.P.2    van Meurs, M.3    Cobelens, P.M.4    Kavelaars, A.5
  • 45
    • 79958140473 scopus 로고    scopus 로고
    • Intravenous immunoglobulin therapy in rheumatic diseases
    • Bayry J, Negi VS, Kaveri SV, (2011) Intravenous immunoglobulin therapy in rheumatic diseases. Nat Rev Rheumatol 7: 349-359.
    • (2011) Nat Rev Rheumatol , vol.7 , pp. 349-359
    • Bayry, J.1    Negi, V.S.2    Kaveri, S.V.3
  • 46
    • 0015857435 scopus 로고
    • Prostaglandin activity in human cutaneous inflammation: detection by radioimmunoassay
    • Goldyne ME, Winkelmann RK, Ryan RJ, (1973) Prostaglandin activity in human cutaneous inflammation: detection by radioimmunoassay. Prostaglandins 4: 737-749.
    • (1973) Prostaglandins , vol.4 , pp. 737-749
    • Goldyne, M.E.1    Winkelmann, R.K.2    Ryan, R.J.3
  • 47
    • 0020646873 scopus 로고
    • Monocyte PGE2 secretion in Hodgkin's disease and its relation to decreased cellular immunity
    • Passwell J, Levanon M, Davidsohn J, Ramot B, (1983) Monocyte PGE2 secretion in Hodgkin's disease and its relation to decreased cellular immunity. Clin Exp Immunol 51: 61-68.
    • (1983) Clin Exp Immunol , vol.51 , pp. 61-68
    • Passwell, J.1    Levanon, M.2    Davidsohn, J.3    Ramot, B.4
  • 48
    • 0021083713 scopus 로고
    • Prostaglandins in breast cancer: relationship to disease stage and hormone status
    • Karmali RA, Welt S, Thaler HT, Lefevre F, (1983) Prostaglandins in breast cancer: relationship to disease stage and hormone status. Br J Cancer 48: 689-696.
    • (1983) Br J Cancer , vol.48 , pp. 689-696
    • Karmali, R.A.1    Welt, S.2    Thaler, H.T.3    Lefevre, F.4
  • 49
    • 79953805083 scopus 로고    scopus 로고
    • Overproduction of cyclo-oxygenase-2 (COX-2) is involved in the resistance to apoptosis in vascular smooth muscle cells from diabetic patients: a link between inflammation and apoptosis
    • Redondo S, Ruiz E, Gordillo-Moscoso A, Navarro-Dorado J, Ramajo M, et al. (2011) Overproduction of cyclo-oxygenase-2 (COX-2) is involved in the resistance to apoptosis in vascular smooth muscle cells from diabetic patients: a link between inflammation and apoptosis. Diabetologia 54: 190-199.
    • (2011) Diabetologia , vol.54 , pp. 190-199
    • Redondo, S.1    Ruiz, E.2    Gordillo-Moscoso, A.3    Navarro-Dorado, J.4    Ramajo, M.5
  • 50
    • 4143124753 scopus 로고    scopus 로고
    • Signal transduction pathways regulating cyclooxygenase-2 expression: potential molecular targets for chemoprevention
    • Chun KS, Surh YJ, (2004) Signal transduction pathways regulating cyclooxygenase-2 expression: potential molecular targets for chemoprevention. Biochem Pharmacol 68: 1089-1100.
    • (2004) Biochem Pharmacol , vol.68 , pp. 1089-1100
    • Chun, K.S.1    Surh, Y.J.2
  • 51
    • 33747028253 scopus 로고    scopus 로고
    • Mediators of PGE2 synthesis and signalling downstream of COX-2 represent potential targets for the prevention/treatment of colorectal cancer
    • Chell S, Kaidi A, Williams AC, Paraskeva C, (2006) Mediators of PGE2 synthesis and signalling downstream of COX-2 represent potential targets for the prevention/treatment of colorectal cancer. Biochim Biophys Acta 1766: 104-119.
    • (2006) Biochim Biophys Acta , vol.1766 , pp. 104-119
    • Chell, S.1    Kaidi, A.2    Williams, A.C.3    Paraskeva, C.4
  • 52
    • 78049438246 scopus 로고    scopus 로고
    • Targeting COX-2 expression by natural compounds: a promising alternative strategy to synthetic COX-2 inhibitors for cancer chemoprevention and therapy
    • Cerella C, Sobolewski C, Dicato M, Diederich M, (2010) Targeting COX-2 expression by natural compounds: a promising alternative strategy to synthetic COX-2 inhibitors for cancer chemoprevention and therapy. Biochem Pharmacol 80: 1801-1815.
    • (2010) Biochem Pharmacol , vol.80 , pp. 1801-1815
    • Cerella, C.1    Sobolewski, C.2    Dicato, M.3    Diederich, M.4
  • 53
    • 0029928405 scopus 로고    scopus 로고
    • Mechanism of action of anti-inflammatory drugs
    • Vane JR, Botting RM, (1996) Mechanism of action of anti-inflammatory drugs. Scand J Rheumatol Suppl 102 pp. 9-21.
    • (1996) Scand J Rheumatol , Issue.SUPPL. 102 , pp. 9-21
    • vane, J.R.1    Botting, R.M.2
  • 54
    • 43549109194 scopus 로고    scopus 로고
    • Anti-inflammatory activity of 4-methoxyhonokiol is a function of the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via NF-kappaB, JNK and p38 MAPK inactivation
    • Zhou HY, Shin EM, Guo LY, Youn UJ, Bae K, et al. (2008) Anti-inflammatory activity of 4-methoxyhonokiol is a function of the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via NF-kappaB, JNK and p38 MAPK inactivation. Eur J Pharmacol 586: 340-349.
    • (2008) Eur J Pharmacol , vol.586 , pp. 340-349
    • Zhou, H.Y.1    Shin, E.M.2    Guo, L.Y.3    Youn, U.J.4    Bae, K.5
  • 55
    • 79956081704 scopus 로고    scopus 로고
    • Evaluation of the anti-inflammatory and anti-tumor effect of ipomoea obscura (L) and its mode of action through the inhibition of pro inflammatory cytokines, nitric oxide and COX-2
    • Hamsa TP, Kuttan G, (2011) Evaluation of the anti-inflammatory and anti-tumor effect of ipomoea obscura (L) and its mode of action through the inhibition of pro inflammatory cytokines, nitric oxide and COX-2. Inflammation 34: 171-183.
    • (2011) Inflammation , vol.34 , pp. 171-183
    • Hamsa, T.P.1    Kuttan, G.2
  • 56
    • 77955384535 scopus 로고    scopus 로고
    • Pharmacologic inhibition of COX-1 and COX-2 in influenza A viral infection in mice
    • Carey MA, Bradbury JA, Rebolloso YD, Graves JP, Zeldin DC, et al. (2010) Pharmacologic inhibition of COX-1 and COX-2 in influenza A viral infection in mice. PLoS One 5: e11610.
    • (2010) PLoS One , vol.5
    • Carey, M.A.1    Bradbury, J.A.2    Rebolloso, Y.D.3    Graves, J.P.4    Zeldin, D.C.5
  • 57
    • 33749633974 scopus 로고    scopus 로고
    • Curcumin down regulates smokeless tobacco-induced NF-kappaB activation and COX-2 expression in human oral premalignant and cancer cells
    • Sharma C, Kaur J, Shishodia S, Aggarwal BB, Ralhan R, (2006) Curcumin down regulates smokeless tobacco-induced NF-kappaB activation and COX-2 expression in human oral premalignant and cancer cells. Toxicology 228: 1-15.
    • (2006) Toxicology , vol.228 , pp. 1-15
    • Sharma, C.1    Kaur, J.2    Shishodia, S.3    Aggarwal, B.B.4    Ralhan, R.5
  • 58
    • 70249136561 scopus 로고    scopus 로고
    • Curcumin sensitizes human colorectal cancer to capecitabine by modulation of cyclin D1, COX-2, MMP-9, VEGF and CXCR4 expression in an orthotopic mouse model
    • Kunnumakkara AB, Diagaradjane P, Anand P, Harikumar KB, Deorukhkar A, et al. (2009) Curcumin sensitizes human colorectal cancer to capecitabine by modulation of cyclin D1, COX-2, MMP-9, VEGF and CXCR4 expression in an orthotopic mouse model. Int J Cancer 125: 2187-2197.
    • (2009) Int J Cancer , vol.125 , pp. 2187-2197
    • Kunnumakkara, A.B.1    Diagaradjane, P.2    Anand, P.3    Harikumar, K.B.4    Deorukhkar, A.5
  • 59
    • 44149088311 scopus 로고    scopus 로고
    • Cancer phytotherapeutics: role for flavonoids at the cellular level
    • Kale A, Gawande S, Kotwal S, (2008) Cancer phytotherapeutics: role for flavonoids at the cellular level. Phytother Res 22: 567-577.
    • (2008) Phytother Res , vol.22 , pp. 567-577
    • Kale, A.1    Gawande, S.2    Kotwal, S.3
  • 60
    • 57349177876 scopus 로고    scopus 로고
    • Ginger extract (Zingiber officinale) has anti-cancer and anti-inflammatory effects on ethionine-induced hepatoma rats
    • Habib SH, Makpol S, Abdul Hamid NA, Das S, Ngah WZ, et al. (2008) Ginger extract (Zingiber officinale) has anti-cancer and anti-inflammatory effects on ethionine-induced hepatoma rats. Clinics (Sao Paulo) 63: 807-813.
    • (2008) Clinics (Sao Paulo) , vol.63 , pp. 807-813
    • Habib, S.H.1    Makpol, S.2    Abdul Hamid, N.A.3    Das, S.4    Ngah, W.Z.5
  • 61
    • 0842327345 scopus 로고    scopus 로고
    • SAR: flavonoids and COX-2 inhibition
    • Rosenkranz HS, Thampatty BP, (2003) SAR: flavonoids and COX-2 inhibition. Oncol Res 13: 529-535.
    • (2003) Oncol Res , vol.13 , pp. 529-535
    • Rosenkranz, H.S.1    Thampatty, B.P.2
  • 62
    • 78650826132 scopus 로고    scopus 로고
    • Anti-inflammatory and anti-cancer activities of essential oils and their biological constituents
    • Torres Salazar A, Hoheisel J, Youns M, Wink M, (2011) Anti-inflammatory and anti-cancer activities of essential oils and their biological constituents. Int J Clin Pharmacol Ther 49: 93-95.
    • (2011) Int J Clin Pharmacol Ther , vol.49 , pp. 93-95
    • Torres Salazar, A.1    Hoheisel, J.2    Youns, M.3    Wink, M.4
  • 63
    • 77957355681 scopus 로고    scopus 로고
    • Anti-inflammatory activity of bark of Dioscorea batatas DECNE through the inhibition of iNOS and COX-2 expressions in RAW264.7 cells via NF-kappaB and ERK1/2 inactivation
    • Jin M, Suh SJ, Yang JH, Lu Y, Kim SJ, et al. (2010) Anti-inflammatory activity of bark of Dioscorea batatas DECNE through the inhibition of iNOS and COX-2 expressions in RAW264.7 cells via NF-kappaB and ERK1/2 inactivation. Food Chem Toxicol 48: 3073-3079.
    • (2010) Food Chem Toxicol , vol.48 , pp. 3073-3079
    • Jin, M.1    Suh, S.J.2    Yang, J.H.3    Lu, Y.4    Kim, S.J.5
  • 64
    • 78650299890 scopus 로고    scopus 로고
    • Anthocyanins from purple sweet potato attenuate dimethylnitrosamine-induced liver injury in rats by inducing Nrf2-mediated antioxidant enzymes and reducing COX-2 and iNOS expression
    • Hwang YP, Choi JH, Yun HJ, Han EH, Kim HG, et al. (2011) Anthocyanins from purple sweet potato attenuate dimethylnitrosamine-induced liver injury in rats by inducing Nrf2-mediated antioxidant enzymes and reducing COX-2 and iNOS expression. Food Chem Toxicol 49: 93-99.
    • (2011) Food Chem Toxicol , vol.49 , pp. 93-99
    • Hwang, Y.P.1    Choi, J.H.2    Yun, H.J.3    Han, E.H.4    Kim, H.G.5
  • 65
    • 31544450725 scopus 로고    scopus 로고
    • Modulation of arachidonic acid metabolism and nitric oxide synthesis by garcinol and its derivatives
    • Hong J, Sang S, Park HJ, Kwon SJ, Suh N, et al. (2006) Modulation of arachidonic acid metabolism and nitric oxide synthesis by garcinol and its derivatives. Carcinogenesis 27: 278-286.
    • (2006) Carcinogenesis , vol.27 , pp. 278-286
    • Hong, J.1    Sang, S.2    Park, H.J.3    Kwon, S.J.4    Suh, N.5
  • 66
    • 84860389531 scopus 로고    scopus 로고
    • Withaferin A down-regulates lipopolysaccharide-induced cyclooxygenase-2 expression and PGE2 production through the inhibition of STAT1/3 activation in microglial cells
    • Min KJ, Choi K, Kwon TK, (2011) Withaferin A down-regulates lipopolysaccharide-induced cyclooxygenase-2 expression and PGE2 production through the inhibition of STAT1/3 activation in microglial cells. Int Immunopharmacol 11: 1137-1142.
    • (2011) Int Immunopharmacol , vol.11 , pp. 1137-1142
    • Min, K.J.1    Choi, K.2    Kwon, T.K.3
  • 67
    • 78649918795 scopus 로고    scopus 로고
    • Anti-inflammatory effects of resveratrol, curcumin and simvastatin in acute small intestinal inflammation
    • Bereswill S, Munoz M, Fischer A, Plickert R, Haag LM, et al. (2010) Anti-inflammatory effects of resveratrol, curcumin and simvastatin in acute small intestinal inflammation. PLoS One 5: e15099.
    • (2010) PLoS One , vol.5
    • Bereswill, S.1    Munoz, M.2    Fischer, A.3    Plickert, R.4    Haag, L.M.5
  • 68
    • 33645089417 scopus 로고    scopus 로고
    • Anti-inflammatory and antinociceptive activity of flavonoids isolated from Viscum album ssp. album
    • Orhan DD, Kupeli E, Yesilada E, Ergun F, (2006) Anti-inflammatory and antinociceptive activity of flavonoids isolated from Viscum album ssp. album. Z Naturforsch C 61: 26-30.
    • (2006) Z Naturforsch C , vol.61 , pp. 26-30
    • Orhan, D.D.1    Kupeli, E.2    Yesilada, E.3    Ergun, F.4
  • 69
    • 3542996933 scopus 로고    scopus 로고
    • Anti-inflammatory effect of Viscum album agglutinin-I (VAA-I): induction of apoptosis in activated neutrophils and inhibition of lipopolysaccharide-induced neutrophilic inflammation in vivo
    • Lavastre V, Cavalli H, Ratthe C, Girard D, (2004) Anti-inflammatory effect of Viscum album agglutinin-I (VAA-I): induction of apoptosis in activated neutrophils and inhibition of lipopolysaccharide-induced neutrophilic inflammation in vivo. Clin Exp Immunol 137: 272-278.
    • (2004) Clin Exp Immunol , vol.137 , pp. 272-278
    • Lavastre, V.1    Cavalli, H.2    Ratthe, C.3    Girard, D.4
  • 70
    • 0029983724 scopus 로고    scopus 로고
    • Distinct isoforms (COX-1 and COX-2) of cyclooxygenase: possible physiological and therapeutic implications
    • Pairet M, Engelhardt G, (1996) Distinct isoforms (COX-1 and COX-2) of cyclooxygenase: possible physiological and therapeutic implications. Fundam Clin Pharmacol 10: 1-17.
    • (1996) Fundam Clin Pharmacol , vol.10 , pp. 1-17
    • Pairet, M.1    Engelhardt, G.2
  • 71
    • 79952116210 scopus 로고    scopus 로고
    • Regulation of endothelial cell functions by basement membrane- and arachidonic acid-derived products
    • Pozzi A, Zent R, (2009) Regulation of endothelial cell functions by basement membrane- and arachidonic acid-derived products. Wiley Interdiscip Rev Syst Biol Med 1: 254-272.
    • (2009) Wiley Interdiscip Rev Syst Biol Med , vol.1 , pp. 254-272
    • Pozzi, A.1    Zent, R.2
  • 72
    • 0029929872 scopus 로고    scopus 로고
    • Antioxidants inhibit interleukin-1-induced cyclooxygenase and nitric-oxide synthase expression in rat mesangial cells. Evidence for post-transcriptional regulation
    • Tetsuka T, Baier LD, Morrison AR, (1996) Antioxidants inhibit interleukin-1-induced cyclooxygenase and nitric-oxide synthase expression in rat mesangial cells. Evidence for post-transcriptional regulation. J Biol Chem 271: 11689-11693.
    • (1996) J Biol Chem , vol.271 , pp. 11689-11693
    • Tetsuka, T.1    Baier, L.D.2    Morrison, A.R.3
  • 73
    • 0033761126 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibition and side-effects of non-steroidal anti-inflammatory drugs in the gastrointestinal tract
    • Meyer-Kirchrath J, Schror K, (2000) Cyclooxygenase-2 inhibition and side-effects of non-steroidal anti-inflammatory drugs in the gastrointestinal tract. Curr Med Chem 7: 1121-1129.
    • (2000) Curr Med Chem , vol.7 , pp. 1121-1129
    • Meyer-Kirchrath, J.1    Schror, K.2
  • 74
    • 0035681660 scopus 로고    scopus 로고
    • Treatment of low back pain with a herbal or synthetic anti-rheumatic: a randomized controlled study. Willow bark extract for low back pain
    • Chrubasik S, Kunzel O, Model A, Conradt C, Black A, (2001) Treatment of low back pain with a herbal or synthetic anti-rheumatic: a randomized controlled study. Willow bark extract for low back pain. Rheumatology (Oxford) 40: 1388-1393.
    • (2001) Rheumatology (Oxford) , vol.40 , pp. 1388-1393
    • Chrubasik, S.1    Kunzel, O.2    Model, A.3    Conradt, C.4    Black, A.5
  • 75
    • 74349116384 scopus 로고    scopus 로고
    • Phytotherapeutics: an evaluation of the potential of 1000 plants
    • Cravotto G, Boffa L, Genzini L, Garella D, (2010) Phytotherapeutics: an evaluation of the potential of 1000 plants. J Clin Pharm Ther 35: 11-48.
    • (2010) J Clin Pharm Ther , vol.35 , pp. 11-48
    • Cravotto, G.1    Boffa, L.2    Genzini, L.3    Garella, D.4


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